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Author Details

Melissa S Love
a Division of The Scripps Research Institute
2012
22
12
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37196868Structure-activity relationship of BMS906024 derivatives for Cryptosporidium parvum growth inhibition.Bioorg Med Chem Lett2023
34748385Pharmacokinetics and Pharmacodynamics of Clofazimine for Treatment of Cryptosporidiosis.Antimicrob Agents Chemother2022
35703552Repurposing the Kinase Inhibitor Mavelertinib for Giardiasis Therapy.Antimicrob Agents Chemother2022
35810253Iron limitation in M. tuberculosis has broad impact on central carbon metabolism.Commun Biol2022
35149760Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance.Commun Biol2022
35134095Pharmacological and genetic activation of cAMP synthesis disrupts cholesterol utilization in Mycobacterium tuberculosis.PLoS Pathog2022
32277809Clofazimine for Treatment of Cryptosporidiosis in Human Immunodeficiency Virus Infected Adults: An Experimental Medicine, Randomized, Double-blind, Placebo-controlled Phase 2a Trial.Clin Infect Dis2021
33740373Repurposing Infectious Disease Hits as Anti-<i>Cryptosporidium</i> Leads.ACS Infect Dis2021
34261904Emerging treatment options for cryptosporidiosis.Curr Opin Infect Dis2021
32892652Phenotypic screening techniques for <i>Cryptosporidium</i> drug discovery.Expert Opin Drug Discov2021
31452169High-Content Screening for Cryptosporidium Drug Discovery.Methods Mol Biol2020
32998973Bicyclic azetidines kill the diarrheal pathogen <i>Cryptosporidium</i> in mice by inhibiting parasite phenylalanyl-tRNA synthetase.Sci Transl Med2020
30894487Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.Proc Natl Acad Sci U S A2019
31249291Identification of a potent benzoxaborole drug candidate for treating cryptosporidiosis.Nat Commun2019
31015448A suite of phenotypic assays to ensure pipeline diversity when prioritizing drug-like Cryptosporidium growth inhibitors.Nat Commun2019
29339392A Novel Piperazine-Based Drug Lead for Cryptosporidiosis from the Medicines for Malaria Venture Open-Access Malaria Box.Antimicrob Agents Chemother2018
30282735The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis.Proc Natl Acad Sci U S A2018
29469575Herbicidins from Streptomyces sp. CB01388 Showing Anti- Cryptosporidium Activity.J Nat Prod2018
28899690Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis.Int J Parasitol2017
28158186A high-throughput phenotypic screen identifies clofazimine as a potential treatment for cryptosporidiosis.PLoS Negl Trop Dis2017
23332153A host GPCR signaling network required for the cytolysis of infected cells facilitates release of apicomplexan parasites.Cell Host Microbe2013
23245326Platelet factor 4 activity against P. falciparum and its translation to nonpeptidic mimics as antimalarials.Cell Host Microbe2012
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Collaborators

Case W McNamara
a division of The Scripps Research Institute La Jolla
Co-authored papers 18
Wesley C Van Voorhis
Center for Emerging and Re-emerging Infectious Diseases, University of Washington
Co-authored papers 5
Elizabeth A Winzeler
University of California San Diego
Co-authored papers 2
Lluis Ballell
Global Health Pharma Unit
Co-authored papers 1
Patricia M Kane
SUNY Upstate Medical University
Co-authored papers 1
Krypton Carolino
University of California
Co-authored papers 1
Stuart L Schreiber
Broad Institute
Co-authored papers 1
Prianka Kumar
The George Washington University School of Medicine and Health Sciences
Co-authored papers 1
Gregory M Goldgof
University of California san francisco
Co-authored papers 1
Andrea L Cheung
University of California
Co-authored papers 1
Jennifer Yang
Chang Gung Memorial Hospital
Co-authored papers 1
Leah E Cowen
University of Toronto
Co-authored papers 1
Jacob D Durrant
University of Pittsburgh
Co-authored papers 1
Peter J Myler
University of Guelph
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Reysha Patel
University of California
Co-authored papers 1
William H Gerwick
Scripps Institution of Oceanography, University of California San Diego
Co-authored papers 1
Jeremy M Rock
The Rockefeller University
Co-authored papers 1
Sabine Ottilie
University of California San Diego
Co-authored papers 1
Matthew Abraham
University of California
Co-authored papers 1
Emmanuelle LeBlanc
University of Toronto
Co-authored papers 1
Amanda K Lukens
Harvard T.H. Chan School of Public Health
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Andrew I Su
The Scripps Research Institute
Co-authored papers 1
Yoshiyuki Suzuki
Nagoya City University
Co-authored papers 1
Dyann F Wirth
The Broad Institute
Co-authored papers 1
Gisel Lopez
University of California
Co-authored papers 1
Karla P Godinez-Macias
University of California
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Hyunil Jo
Department of Pharmaceutical Chemistry, University of California San Francisco
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Madeline R Luth
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Release 1.2