Author details

Full Name

Richard S Judson

Affiliation

ORCID

Career Start Year

1990

Papers

168

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36850973	A Machine Learning Model to Estimate Toxicokinetic Half-Lives of Per- and Polyfluoro-Alkyl Substances (PFAS) in Multiple Species.		2023
38043774	Exploring the effects of experimental parameters and data modeling approaches on in vitro transcriptomic point-of-departure estimates.		2023
37990691	Reproducibility of organ-level effects in repeat dose animal studies.		2023
37288009	From vision toward best practices: Evaluating transcriptomic points of departure for application in risk assessment using a uniform workflow.		2023
36989077	Probabilistic Points of Departure and Reference Doses for Characterizing Human Noncancer and Developmental/Reproductive Effects for 10,145 Chemicals.		2023
35246223	Predicting molecular initiating events using chemical target annotations and gene expression.	BioData Mining	2022
36301716	Navigating Transcriptomic Connectivity Mapping Workflows to Link Chemicals with Bioactivities.	Chemical Research in Toxicology	2022
35580034	Systematic Evidence Map for Over One Hundred and Fifty Per- and Polyfluoroalkyl Substances (PFAS).	Environmental Health Perspectives	2022
35483669	Combining phenotypic profiling and targeted RNA-Seq reveals linkages between transcriptional perturbations and chemical effects on cell morphology: Retinoic acid as an example.	Toxicology and Applied Pharmacology	2022
36122840	Evaluation of a rapid, generic human gestational dose model.	Reproductive Toxicology	2022
37841081	Evaluating structure-based activity in a high-throughput assay for steroid biosynthesis.		2022
36969381	Towards reproducible structure-based chemical categories for PFAS to inform and evaluate toxicity and toxicokinetic testing.		2022
34791027	tcplfit2: an R-language general purpose concentration-response modeling package.		2022
35128218	Integrating publicly available information to screen potential candidates for chemical prioritization under the Toxic Substances Control Act: A proof of concept case study using genotoxicity and carcinogenicity.	Comput Toxicol	2021
33538836	High-Throughput Transcriptomics Platform for Screening Environmental Chemicals.	Toxicological Sciences	2021
34140756	Exposure and Toxicity Characterization of Chemical Emissions and Chemicals in Products: Global Recommendations and Implementation in USEtox.	International Journal of Life Cycle Assessment	2021
33140634	The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology.	Chem Res Toxicol	2021
32862757	Comparison of Approaches for Determining Bioactivity Hits from High-Dimensional Profiling Data.	SLAS Discovery	2021
33401053	Integrating endocrine-related health effects into comparative human toxicity characterization.	Science of the Total Environment	2021
34504984	Evaluation of Existing QSAR Models and Structural Alerts and Development of New Ensemble Models for Genotoxicity Using a Newly Compiled Experimental Dataset.	Comput Toxicol	2021
31471948	Characterizing cleft palate toxicants using ToxCast data, chemical structure, and the biomedical literature.	Birth Defects Research	2020
32074470	CoMPARA: Collaborative Modeling Project for Androgen Receptor Activity.	Environ Health Perspect	2020
32132587	High-Throughput Screening to Predict Chemical-Assay Interference.	Scientific Reports	2020
32073639	Profiling the ToxCast Library With a Pluripotent Human (H9) Stem Cell Line-Based Biomarker Assay for Developmental Toxicity.	Toxicological Sciences	2020
31669395	Vision of a near future: Bridging the human health-environment divide. Toward an integrated strategy to understand mechanisms across species for chemical safety assessment.	Toxicol In Vitro	2020
34017928	Structure-based QSAR Models to Predict Repeat Dose Toxicity Points of Departure.	Computational Toxicology	2020
34124416	Using Chemical Structure Information to Develop Predictive Models for Toxicokinetic Parameters to Inform High-throughput Risk-assessment.	Computational Toxicology	2020
32529217	Corrigendum to: "Profiling the ToxCast Library With a Pluripotent Human (H9) Stem Cell Line-Based Biomarker Assay for Developmental Toxicity".	Toxicological Sciences	2020
32798611	Selecting a minimal set of androgen receptor assays for screening chemicals.	Regulatory Toxicology and Pharmacology	2020
31095702	Challenges in IBD Research: Environmental Triggers.	Inflamm Bowel Dis	2019
31676319	Development of a prioritization method for chemical-mediated effects on steroidogenesis using an integrated statistical analysis of high-throughput H295R data.	Regulatory Toxicology and Pharmacology	2019
31560848	Ensemble QSAR Modeling to Predict Multispecies Fish Toxicity Lethal Concentrations and Points of Departure.	Environmental Science & Technology	2019
30359698	Integrating data gap filling techniques: A case study predicting TEFs for neurotoxicity TEQs to facilitate the hazard assessment of polychlorinated biphenyls.	Regulatory Toxicology and Pharmacology	2019
30218698	Assessing bioactivity-exposure profiles of fruit and vegetable extracts in the BioMAP profiling system.	Toxicology in Vitro	2019
30584954	Development, validation and integration of in silico models to identify androgen active chemicals.		2019
30570668	Workflow for defining reference chemicals for assessing performance of in vitro assays.	Altex	2019
31501805	Considerations for Strategic Use of High-Throughput Transcriptomics Chemical Screening Data in Regulatory Decisions.	Curr Opin Toxicol	2019
31404555	Progress in data interoperability to support computational toxicology and chemical safety evaluation.	Toxicology and Applied Pharmacology	2019
31121201	Predicting estrogen receptor activation by a group of substituted phenols: An integrated approach to testing and assessment case study.	Regulatory Toxicology and Pharmacology	2019
30835285	The Next Generation Blueprint of Computational Toxicology at the U.S. Environmental Protection Agency.	Toxicol Sci	2019
31325560	Identification of potential endocrine disrupting chemicals using gene expression biomarkers.	Toxicology and Applied Pharmacology	2019
29462216	A hybrid gene selection approach to create the S1500+ targeted gene sets for use in high-throughput transcriptomics.	PLoS One	2018
36779220	A Mechanistic Framework for Integrating Chemical Structure and High-Throughput Screening Results to Improve Toxicity Predictions.		2018
30205137	Evaluation of androgen assay results using a curated Hershberger database.	Reproductive Toxicology	2018
30205136	Development of a curated Hershberger database.	Reproductive Toxicology	2018
30540492	Advancements in Life Cycle Human Exposure and Toxicity Characterization.	Environmental Health Perspectives	2018
30044784	Uncertainty quantification in ToxCast high throughput screening.	PLoS ONE	2018
30229396	Exploring non-linear distance metrics in the structure-activity space: QSAR models for human estrogen receptor.	Journal of Cheminformatics	2018
29939356	Erratum to "High-Throughput H295R Steroidogenesis Assay: Utility as an Alternative and a Statistical Approach to Characterize Effects on Steroidogenesis".	Toxicological Sciences	2018
29520515	OPERA models for predicting physicochemical properties and environmental fate endpoints.	Journal of Cheminformatics	2018