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Author Details

Jerold Chun
1987
325
101
PMIDPaper TitleJournal TitlePublished Year
37137584Activation of skeletal muscle FAPs by LPA requires the Hippo signaling via the FAK pathway.2023
36399263Extraction and Purification of Single Nuclei from Frozen Human Brain Tissue.Methods in Molecular Biology2023
37645998Mapping Human Tissues with Highly Multiplexed RNA in situ Hybridization.bioRxiv2023
37149155Molecular and neuroimmune pharmacology of S1P receptor modulators and other disease-modifying therapies for multiple sclerosis.2023
35094654S1P/S1PR3 signalling axis protects against obesity-induced metabolic dysfunction.Adipocyte2022
35464399Lysophosphatidic Acid Receptor 3 Suppress Neutrophil Extracellular Traps Production and Thrombosis During Sepsis.Frontiers in Immunology2022
36242998Somatic genomic mosaicism in the brain: Identified mutations provide challenges and opportunities for the clinic.Med2022
35385768Activation of the ATX/LPA/LPARs axis induces a fibrotic response in skeletal muscle.Matrix Biology2022
35948083Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA), UCM-14216, Ameliorates Spinal Cord Injury in Mice.Journal of Medicinal Chemistry2022
36072569CAQK, a peptide associating with extracellular matrix components targets sites of demyelinating injuries.Frontiers in Cellular Neuroscience2022
35725892The Two Sides of Siponimod: Evidence for Brain and Immune Mechanisms in Multiple Sclerosis.CNS Drugs2022
35409312Sphingosine 1-Phosphate Receptor 5 (S1P) Knockout Ameliorates Adenine-Induced Nephropathy.International Journal of Molecular Sciences2022
35406635Lysophosphatidic Acid Receptor 5 (LPA) Knockout Ameliorates the Neuroinflammatory Response In Vivo and Modifies the Inflammatory and Metabolic Landscape of Primary Microglia In Vitro.Cells2022
35920162LPA Contributes to Vascular Endothelium Homeostasis and Cardiac Remodeling After Myocardial Infarction.Circulation Research2022
35783097Single-Nucleus RNA-seq of Normal-Appearing Brain Regions in Relapsing-Remitting vs. Secondary Progressive Multiple Sclerosis: Implications for the Efficacy of Fingolimod.Frontiers in Cellular Neuroscience2022
35319013Author Correction: Comparative cellular analysis of motor cortex in human, marmoset and mouse.Nature2022
34986275Ponesimod inhibits astrocyte-mediated neuroinflammation and protects against cingulum demyelination via S1P -selective modulation.FASEB Journal2022
34677611Sphingosine 1-phosphate receptor 5 (S1PR5) regulates the peripheral retention of tissue-resident lymphocytes.Journal of Experimental Medicine2022
35026421Pain-like behavior in the collagen antibody-induced arthritis model is regulated by lysophosphatidic acid and activation of satellite glia cells.Brain, Behavior, and Immunity2022
35136060Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate.Nature Communications2022
34529832THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors.Br J Pharmacol2021
33853612Lysophosphatidic acid (LPA)-antibody (504B3) engagement detected by interferometry identifies off-target binding.Lipids in Health and Disease2021
33792787GABAergic deficits in absence of LPA receptor, associated anxiety-like and coping behaviors, and amelioration by interneuron precursor transplants into the dorsal hippocampus.Brain Structure and Function2021
33893167S1P-Gα Signaling Controls Astrocytic Glutamate Uptake and Mitochondrial Oxygen Consumption.eNeuro2021
33841099Dual Role of Lysophosphatidic Acid Receptor 2 (LPA) in Amyotrophic Lateral Sclerosis.Frontiers in Cellular Neuroscience2021
33510165LPA signaling acts as a cell-extrinsic mechanism to initiate cilia disassembly and promote neurogenesis.Nature Communications2021
33925035A Soluble Epoxide Hydrolase Inhibitor, 1-TrifluoromethoxyPhenyl-3-(1-Propionylpiperidin-4-yl) Urea, Ameliorates Experimental Autoimmune Encephalomyelitis.International Journal of Molecular Sciences2021
34356087Genomic Mosaicism Formed by Somatic Variation in the Aging and Diseased Brain.Genes2021
33152386Chronic central modulation of LPA/LPA receptors-signaling pathway in the mouse brain regulates cognition, emotion, and hippocampal neurogenesis.Progress in Neuro-Psychopharmacology and Biological Psychiatry2021
33301355Endothelial S1P Signaling Counteracts Infarct Expansion in Ischemic Stroke.Circulation Research2021
32974731Activation of Macrophages by Lysophosphatidic Acid through the Lysophosphatidic Acid Receptor 1 as a Novel Mechanism in Multiple Sclerosis Pathogenesis.Molecular Neurobiology2021
33289881Sphingosine 1-phosphate Receptor Modulator Therapy for Multiple Sclerosis: Differential Downstream Receptor Signalling and Clinical Profile Effects.Drugs2021
34795060Altered cell and RNA isoform diversity in aging Down syndrome brains.Proceedings of the National Academy of Sciences of the United States of America2021
34618403Deletion of Sphingosine 1-Phosphate receptor 1 in cardiomyocytes during development leads to abnormal ventricular conduction and fibrosis.Physiological Reports2021
34616062Comparative cellular analysis of motor cortex in human, marmoset and mouse.Nature2021
34652685Generation of an Lpar1-EGFP Fusion Knock-in Transgenic Mouse Line.Cell Biochemistry and Biophysics2021
32513900Unlabeled lysophosphatidic acid receptor binding in free solution as determined by a compensated interferometric reader.J Lipid Res2020
32065590Glycerol-3-phosphate is an FGF23 regulator derived from the injured kidney.J Clin Invest2020
32457796Mosaic Somatic Gene Recombination as a Potentially Unifying Hypothesis for Alzheimer's Disease.Frontiers in Genetics2020
32330664Expression of the type 1 lysophosphatidic acid receptor in osteoblastic cell lineage controls both bone mineralization and osteocyte specification.Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids2020
33317583Altered cleavage plane orientation with increased genomic aneuploidy produced by receptor-mediated lysophosphatidic acid (LPA) signaling in mouse cerebral cortical neural progenitor cells.Molecular Brain2020
32929779Conditional Lpar1 gene targeting identifies cell types mediating neuropathic pain.FASEB Journal2020
33042260LPA-mediated lysophosphatidic acid signaling promotes postnatal heart regeneration in mice.Theranostics2020
32699111Brain cell somatic gene recombination and its phylogenetic foundations.Journal of Biological Chemistry2020
31244601Effects of the LPA Receptor Deficiency and Stress on the Hippocampal LPA Species in Mice.Frontiers in Molecular Neuroscience2019
31633020LPA overactivation induces neonatal posthemorrhagic hydrocephalus through ependymal loss and ciliary dysfunction.Science advances2019
31607860CB and LPA Receptors Relationship in the Mouse Central Nervous System.Frontiers in Molecular Neuroscience2019
32206173The Gene Conundrum in Alzheimer's Disease.Cerebrum : the Dana forum on brain science2019
30550929Lysophosphatidic acid receptor type 2 activation contributes to secondary damage after spinal cord injury in mice.Brain, Behavior, and Immunity2019
30625282Fingolimod: Lessons Learned and New Opportunities for Treating Multiple Sclerosis and Other Disorders.Annual Review of Pharmacology and Toxicology2019
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