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Author Details

Scott D Emr
Weill Institute for Cell and Molecular Biology, Cornell University
1978
243
117
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
34415038The Hob proteins are novel and conserved lipid-binding proteins at ER-PM contact sites.J Cell Sci2022
35770973Adaptor linked K63 di-ubiquitin activates Nedd4/Rsp5 E3 ligase.Elife2022
35800464Immunoisolation of Endosomal Recycling Vesicles from <i>Saccharomyces cerevisiae</i>.Bio Protoc2022
35363519Recruitment and organization of ESCRT-0 and ubiquitinated cargo via condensation.Sci Adv2022
33414051Membrane Protein Quality Control Mechanisms in the Endo-Lysosome System.Trends Cell Biol2021
34821548Golgi membrane protein Erd1 Is essential for recycling a subset of Golgi glycosyltransferases.Elife2021
34524084A PX-BAR protein Mvp1/SNX8 and a dynamin-like GTPase Vps1 drive endosomal recycling.Elife2021
34028356Design principles of the ESCRT-III Vps24-Vps2 module.Elife2021
32267208ESCRT-III and ER-PM contacts maintain lipid homeostasis.Mol Biol Cell2020
32421152Calcineurin-dependent regulation of endocytosis by a plasma membrane ubiquitin ligase adaptor, Rcr1.J Cell Biol2020
30361468Rsp5 Ubiquitin ligase-mediated quality control system clears membrane proteins mistargeted to the vacuole membrane.J Cell Biol2019
31246173Electrostatic lateral interactions drive ESCRT-III heteropolymer assembly.Elife2019
31337624A bipartite sorting signal ensures specificity of retromer complex in membrane protein recycling.J Cell Biol2019
31250297Genetic and Biochemical Analyses of Yeast ESCRT.Methods Mol Biol2019
31618110Activity of a ubiquitin ligase adaptor is regulated by disordered insertions in its arrestin domain.Mol Biol Cell2019
30894536Coming together to define membrane contact sites.Nat Commun2019
30910024Methods for studying the regulation of membrane traffic by ubiquitin and the ESCRT pathway.Methods Enzymol2019
29511122Membrane protein recycling from the vacuole/lysosome membrane.J Cell Biol2018
29995558Retrograde trafficking from the vacuole/lysosome membrane.Autophagy2018
28661397ESCRTs function directly on the lysosome membrane to downregulate ubiquitinated lysosomal membrane proteins.Elife2017
28298493Deubiquitinating enzymes Ubp2 and Ubp15 regulate endocytosis by limiting ubiquitination and degradation of ARTs.Mol Biol Cell2017
26864629Phosphoinositide kinase signaling controls ER-PM cross-talk.Mol Biol Cell2016
27798240Identification of the endocytic sorting signal recognized by the Art1-Rsp5 ubiquitin ligase complex.Mol Biol Cell2016
27074665ESCRT-III activation by parallel action of ESCRT-I/II and ESCRT-0/Bro1 during MVB biogenesis.Elife2016
25620559Ubiquitin-dependent lysosomal membrane protein sorting and degradation.Mol Cell2015
26670543Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments.Elife2015
26527740Membrane-anchored ubiquitin ligase complex is required for the turnover of lysosomal membrane proteins.J Cell Biol2015
26283797Mdm1/Snx13 is a novel ER-endolysosomal interorganelle tethering protein.J Cell Biol2015
26025028Molecular mechanisms of inter-organelle ER-PM contact sites.Curr Opin Cell Biol2015
23522446ER-PM connections: sites of information transfer and inter-organelle communication.Curr Opin Cell Biol2013
24139821Essential N-terminal insertion motif anchors the ESCRT-III filament during MVB vesicle formation.Dev Cell2013
24215073A Nobel Prize for membrane traffic: vesicles find their journey's end.J Cell Biol2013
24003212Molecular mechanisms of the membrane sculpting ESCRT pathway.Cold Spring Harb Perspect Biol2013
23599894The ART-Rsp5 ubiquitin ligase network comprises a plasma membrane quality control system that protects yeast cells from proteotoxic stress.Elife2013
23733183The phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2)-dependent Tup1 conversion (PIPTC) regulates metabolic reprogramming from glycolysis to gluconeogenesis.J Biol Chem2013
22370727Cargo ubiquitination is essential for multivesicular body intralumenal vesicle formation.EMBO Rep2012
23237950ER-to-plasma membrane tethering proteins regulate cell signaling and ER morphology.Dev Cell2012
23063125The endosomal sorting complex ESCRT-II mediates the assembly and architecture of ESCRT-III helices.Cell2012
22562153The dual PH domain protein Opy1 functions as a sensor and modulator of PtdIns(4,5)Pâ¿¿ synthesis.EMBO J2012
22404628Ubiquitin and membrane protein turnover: from cradle to grave.Annu Rev Biochem2012
21295699Osh proteins regulate phosphoinositide metabolism at ER-plasma membrane contact sites.Cell2011
22123866Eisosome proteins assemble into a membrane scaffold.J Cell Biol2011
22118465TORC1 regulates endocytosis via Npr1-mediated phosphoinhibition of a ubiquitin ligase adaptor.Cell2011
21824003Genetic interactions with mutations affecting septin assembly reveal ESCRT functions in budding yeast cytokinesis.Biol Chem2011
21763610The ESCRT pathway.Dev Cell2011
21880895Two novel WD40 domain-containing proteins, Ere1 and Ere2, function in the retromer-mediated endosomal recycling pathway.Mol Biol Cell2011
21536737Phosphoinositide [PI(3,5)P2] lipid-dependent regulation of the general transcriptional regulator Tup1.Genes Dev2011
20389282Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function.EMBO J2010
20547860Pheromone-induced anisotropy in yeast plasma membrane phosphatidylinositol-4,5-bisphosphate distribution is required for MAPK signaling.Proc Natl Acad Sci U S A2010
20134403ESCRT-II coordinates the assembly of ESCRT-III filaments for cargo sorting and multivesicular body vesicle formation.EMBO J2010
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Collaborators

University College London
Co-authored papers 20
Yale School of Medicine
Co-authored papers 10
Co-authored papers 7
University of Toronto
Co-authored papers 3
University of California Berkeley
Co-authored papers 3
University of Alberta
Co-authored papers 3
University of Toronto
Co-authored papers 3
Weill Institute for Cell and Molecular Biology, Cornell University
Co-authored papers 2
Medical Research Council Laboratory of Molecular Biology
Co-authored papers 1
University of California San Diego
Co-authored papers 1
Harvard T. H. Chan School of Public Health
Co-authored papers 1
Genentech Inc.
Co-authored papers 1
Leibniz Institute of Virology
Co-authored papers 1
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
University of Virginia
Co-authored papers 1
University of Utah School of Medicine
Co-authored papers 1
Wake Forest University
Co-authored papers 1
The University of Texas Health Science Center at Houston
Co-authored papers 1
Center for Cancer Research, National Institutes of Health
Co-authored papers 1
Stanford University School of Medicine, Center for Clinical Sciences Research
Co-authored papers 1
National Cancer Institute, USA and Center for Strategic Scientific Initiatives
Co-authored papers 1
University of California San Diego
Co-authored papers 1
Max Planck Institute of Biochemistry
Co-authored papers 1
Heersink School of Medicine, University of Alabama at Birmingham
Co-authored papers 1
Max Planck Institute of Biochemistry
Co-authored papers 1
Northwestern University
Co-authored papers 1
Washington University School of Medicine
Co-authored papers 1
The Genome Institute at Washington University
Co-authored papers 1
Lukasiewicz Research Network-PORT Polish Center for Technology Development
Co-authored papers 1