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Author Details
Full Name
Scott D Emr
Affiliation
Weill Institute for Cell and Molecular Biology, Cornell University
ORCID
Career Start Year
1978
Papers
243
H Index
117
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
34415038
The Hob proteins are novel and conserved lipid-binding proteins at ER-PM contact sites.
J Cell Sci
2022
35770973
Adaptor linked K63 di-ubiquitin activates Nedd4/Rsp5 E3 ligase.
Elife
2022
35800464
Immunoisolation of Endosomal Recycling Vesicles from <i>Saccharomyces cerevisiae</i>.
Bio Protoc
2022
35363519
Recruitment and organization of ESCRT-0 and ubiquitinated cargo via condensation.
Sci Adv
2022
33414051
Membrane Protein Quality Control Mechanisms in the Endo-Lysosome System.
Trends Cell Biol
2021
34821548
Golgi membrane protein Erd1 Is essential for recycling a subset of Golgi glycosyltransferases.
Elife
2021
34524084
A PX-BAR protein Mvp1/SNX8 and a dynamin-like GTPase Vps1 drive endosomal recycling.
Elife
2021
34028356
Design principles of the ESCRT-III Vps24-Vps2 module.
Elife
2021
32267208
ESCRT-III and ER-PM contacts maintain lipid homeostasis.
Mol Biol Cell
2020
32421152
Calcineurin-dependent regulation of endocytosis by a plasma membrane ubiquitin ligase adaptor, Rcr1.
J Cell Biol
2020
30361468
Rsp5 Ubiquitin ligase-mediated quality control system clears membrane proteins mistargeted to the vacuole membrane.
J Cell Biol
2019
31246173
Electrostatic lateral interactions drive ESCRT-III heteropolymer assembly.
Elife
2019
31337624
A bipartite sorting signal ensures specificity of retromer complex in membrane protein recycling.
J Cell Biol
2019
31250297
Genetic and Biochemical Analyses of Yeast ESCRT.
Methods Mol Biol
2019
31618110
Activity of a ubiquitin ligase adaptor is regulated by disordered insertions in its arrestin domain.
Mol Biol Cell
2019
30894536
Coming together to define membrane contact sites.
Nat Commun
2019
30910024
Methods for studying the regulation of membrane traffic by ubiquitin and the ESCRT pathway.
Methods Enzymol
2019
29511122
Membrane protein recycling from the vacuole/lysosome membrane.
J Cell Biol
2018
29995558
Retrograde trafficking from the vacuole/lysosome membrane.
Autophagy
2018
28661397
ESCRTs function directly on the lysosome membrane to downregulate ubiquitinated lysosomal membrane proteins.
Elife
2017
28298493
Deubiquitinating enzymes Ubp2 and Ubp15 regulate endocytosis by limiting ubiquitination and degradation of ARTs.
Mol Biol Cell
2017
26864629
Phosphoinositide kinase signaling controls ER-PM cross-talk.
Mol Biol Cell
2016
27798240
Identification of the endocytic sorting signal recognized by the Art1-Rsp5 ubiquitin ligase complex.
Mol Biol Cell
2016
27074665
ESCRT-III activation by parallel action of ESCRT-I/II and ESCRT-0/Bro1 during MVB biogenesis.
Elife
2016
25620559
Ubiquitin-dependent lysosomal membrane protein sorting and degradation.
Mol Cell
2015
26670543
Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments.
Elife
2015
26527740
Membrane-anchored ubiquitin ligase complex is required for the turnover of lysosomal membrane proteins.
J Cell Biol
2015
26283797
Mdm1/Snx13 is a novel ER-endolysosomal interorganelle tethering protein.
J Cell Biol
2015
26025028
Molecular mechanisms of inter-organelle ER-PM contact sites.
Curr Opin Cell Biol
2015
23522446
ER-PM connections: sites of information transfer and inter-organelle communication.
Curr Opin Cell Biol
2013
24139821
Essential N-terminal insertion motif anchors the ESCRT-III filament during MVB vesicle formation.
Dev Cell
2013
24215073
A Nobel Prize for membrane traffic: vesicles find their journey's end.
J Cell Biol
2013
24003212
Molecular mechanisms of the membrane sculpting ESCRT pathway.
Cold Spring Harb Perspect Biol
2013
23599894
The ART-Rsp5 ubiquitin ligase network comprises a plasma membrane quality control system that protects yeast cells from proteotoxic stress.
Elife
2013
23733183
The phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2)-dependent Tup1 conversion (PIPTC) regulates metabolic reprogramming from glycolysis to gluconeogenesis.
J Biol Chem
2013
22370727
Cargo ubiquitination is essential for multivesicular body intralumenal vesicle formation.
EMBO Rep
2012
23237950
ER-to-plasma membrane tethering proteins regulate cell signaling and ER morphology.
Dev Cell
2012
23063125
The endosomal sorting complex ESCRT-II mediates the assembly and architecture of ESCRT-III helices.
Cell
2012
22562153
The dual PH domain protein Opy1 functions as a sensor and modulator of PtdIns(4,5)Pâ¿¿ synthesis.
EMBO J
2012
22404628
Ubiquitin and membrane protein turnover: from cradle to grave.
Annu Rev Biochem
2012
21295699
Osh proteins regulate phosphoinositide metabolism at ER-plasma membrane contact sites.
Cell
2011
22123866
Eisosome proteins assemble into a membrane scaffold.
J Cell Biol
2011
22118465
TORC1 regulates endocytosis via Npr1-mediated phosphoinhibition of a ubiquitin ligase adaptor.
Cell
2011
21824003
Genetic interactions with mutations affecting septin assembly reveal ESCRT functions in budding yeast cytokinesis.
Biol Chem
2011
21763610
The ESCRT pathway.
Dev Cell
2011
21880895
Two novel WD40 domain-containing proteins, Ere1 and Ere2, function in the retromer-mediated endosomal recycling pathway.
Mol Biol Cell
2011
21536737
Phosphoinositide [PI(3,5)P2] lipid-dependent regulation of the general transcriptional regulator Tup1.
Genes Dev
2011
20389282
Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function.
EMBO J
2010
20547860
Pheromone-induced anisotropy in yeast plasma membrane phosphatidylinositol-4,5-bisphosphate distribution is required for MAPK signaling.
Proc Natl Acad Sci U S A
2010
20134403
ESCRT-II coordinates the assembly of ESCRT-III filaments for cargo sorting and multivesicular body vesicle formation.
EMBO J
2010
1 - 50 of 243
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University of Virginia
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