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Author Details

Frederic Leblond
Centre de recherche du Centre hospitalier de l'Universite de Montreal
1999
89
28
PMIDPaper TitleJournal TitlePublished Year
36825245Open-sourced Raman spectroscopy data processing package implementing a baseline removal algorithm validated from multiple datasets acquired in human tissue and biofluids.J Biomed Opt2023
37530390Detection of SARS-CoV-2 in saliva by a low-cost LSPR-based sensor.Anal Methods2023
37342685Spectral focusing-based stimulated Raman scattering microscopy using compact glass blocks for adjustable dispersion.Biomed Opt Express2023
37009577<i>In situ</i> Raman spectroscopy and machine learning unveil biomolecular alterations in invasive breast cancer.J Biomed Opt2023
37038988A clinical Raman spectroscopy imaging system and safety requirements for <i>in situ</i> intraoperative tissue characterization.Analyst2023
37265877Preclinical evaluation of Raman spectroscopy for pedicular screw insertion surgical guidance in a porcine spine model.J Biomed Opt2023
34676670Time-gated interferometric detection increases Raman scattering to fluorescence signal ratio in biological samples.J Biophotonics2022
36589558Multispectral intraoperative imaging for the detection of the hemodynamic response to interictal epileptiform discharges.Biomed Opt Express2022
36045491Image-guided Raman spectroscopy navigation system to improve transperineal prostate cancer detection. Part 1: Raman spectroscopy fiber-optics system and in situ tissue characterization.J Biomed Opt2022
36085571Image-guided Raman spectroscopy navigation system to improve transperineal prostate cancer detection. Part 2: in-vivo tumor-targeting using a classification model combining spectral and MRI-radiomics features.J Biomed Opt2022
35142113Saliva-based detection of COVID-19 infection in a real-world setting using reagent-free Raman spectroscopy and machine learning.J Biomed Opt2022
34837331Multispectral label-free Raman spectroscopy can detect ovarian and endometrial cancer with high accuracy.J Biophotonics2022
33973425Special Series Guest Editorial: Artificial Intelligence and Machine Learning in Biomedical Optics.J Biomed Opt2021
33580641Handheld macroscopic Raman spectroscopy imaging instrument for machine-learning-based molecular tissue margins characterization.J Biomed Opt2021
34743445Dimensional reduction based on peak fitting of Raman micro spectroscopy data improves detection of prostate cancer in tissue specimens.J Biomed Opt2021
32341866Wide-field optical spectroscopy system integrating reflectance and spatial frequency domain imaging to measure attenuation-corrected intrinsic tissue fluorescence in radical prostatectomy specimens.Biomed Opt Express2020
33111509Experimental validation of a spectroscopic Monte Carlo light transport simulation technique and Raman scattering depth sensing analysis in biological tissue.J Biomed Opt2020
33179457Multispectral diffuse reflectance can discriminate blood vessels and bleeding during neurosurgery based on low-frequency hemodynamics.J Biomed Opt2020
32797086Identification of intraductal carcinoma of the prostate on tissue specimens using Raman micro-spectroscopy: A diagnostic accuracy case-control study with multicohort validation.PLoS Med2020
32358930Rise of Raman spectroscopy in neurosurgery: a review.J Biomed Opt2020
32227280Pre-clinical evaluation of an image-guided in-situ Raman spectroscopy navigation system for targeted prostate cancer interventions.Int J Comput Assist Radiol Surg2020
32319263Quantitative spectral quality assessment technique validated using intraoperative in vivo Raman spectroscopy measurements.J Biomed Opt2020
30636032Development and first in-human use of a Raman spectroscopy guidance system integrated with a brain biopsy needle.J Biophotonics2019
31647061Feature engineering applied to intraoperative in vivo Raman spectroscopy sheds light on molecular processes in brain cancer: a retrospective study of 65 patients.Analyst2019
31037243Interstitial imaging with multiple diffusive reflectance spectroscopy projections for <i>in vivo</i> blood vessels detection during brain needle biopsy procedures.Neurophotonics2019
30767440Integration of a Raman spectroscopy system to a robotic-assisted surgical system for real-time tissue characterization during radical prostatectomy procedures.J Biomed Opt2019
31172192Long-term fluorescence hyperspectral imaging of on-chip treated co-culture tumour spheroids to follow clonal evolution.Integr Biol (Camb)2019
30358162Quantitative subsurface spatial frequency-domain fluorescence imaging for enhanced glioma resection.J Biophotonics2019
28777025Red-light excitation of protoporphyrin IX fluorescence for subsurface tumor detection.J Neurosurg2018
29999046Fluorescence hyperspectral imaging for live monitoring of multiple spheroids in microfluidic chips.Analyst2018
30615702Combining high wavenumber and fingerprint Raman spectroscopy for the detection of prostate cancer during radical prostatectomy.Biomed Opt Express2018
29379121A new method using Raman spectroscopy for in vivo targeted brain cancer tissue biopsy.Sci Rep2018
29542855Mesoscopic characterization of prostate cancer using Raman spectroscopy: potential for diagnostics and therapeutics.BJU Int2018
29512358Challenges and opportunities in clinical translation of biomedical optical spectroscopy and imaging.J Biomed Opt2018
29106741Development and characterization of a handheld hyperspectral Raman imaging probe system for molecular characterization of tissue on mesoscopic scales.Med Phys2018
27845785Raman spectroscopy in microsurgery: impact of operating microscope illumination sources on data quality and tissue classification.Analyst2017
28358157Optical diagnosis - highlighting the clinical applications of vibrational spectroscopy.Analyst2017
29057287Dimension reduction technique using a multilayered descriptor for high-precision classification of ovarian cancer tissue using optical coherence tomography: a feasibility study.J Med Imaging (Bellingham)2017
28856042Fluorescence depth estimation from wide-field optical imaging data for guiding brain tumor resection: a multi-inclusion phantom study.Biomed Opt Express2017
28697235Preclinical evaluation of spatial frequency domain-enabled wide-field quantitative imaging for enhanced glioma resection.J Biomed Opt2017
28659435Highly Accurate Detection of Cancer <i>In Situ</i> with Intraoperative, Label-Free, Multimodal Optical Spectroscopy.Cancer Res2017
27804917A review of Raman spectroscopy advances with an emphasis on clinical translation challenges in oncology.Phys Med Biol2016
28018730Raman spectroscopy detects distant invasive brain cancer cells centimeters beyond MRI capability in humans.Biomed Opt Express2016
28005869Wide-field spontaneous Raman spectroscopy imaging system for biological tissue interrogation.Opt Lett2016
27604560Neural networks improve brain cancer detection with Raman spectroscopy in the presence of operating room light artifacts.J Biomed Opt2016
27752519Intraoperative video-rate hemodynamic response assessment in human cortex using snapshot hyperspectral optical imaging.Neurophotonics2016
25793562Macroscopic-imaging technique for subsurface quantification of near-infrared markers during surgery.J Biomed Opt2015
26600990Sensitivity analysis aimed at blood vessels detection using interstitial optical tomography during brain needle biopsy procedures.Biomed Opt Express2015
26713218Improved sensitivity to fluorescence for cancer detection in wide-field image-guided neurosurgery.Biomed Opt Express2015
26713211Introduction to the optics and the brain 2015 feature issue.Biomed Opt Express2015
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Collaborators

Institut du cancer de Montreal
Co-authored papers 22
INSERM UMR_S9 and Universite de Strasbourg, Institut d'immunologie et d'hematologie
Co-authored papers 9
Co-authored papers 8
Centre de recherche du Centre Hospitalier de l'Universite de Montreal
Co-authored papers 7
Centre de recherche du Centre hospitalier de l'Universite de Montreal
Co-authored papers 7
University of Montreal Health Center
Co-authored papers 6
Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center
Co-authored papers 4
Centre Hospitalier de l'Universite de Montreal
Co-authored papers 4
Centre de Recherche du Centre Hospitalier de l'Universite de Montreal (CRCHUM)
Co-authored papers 4
Centre hospitalier de l'Universite de Montreal
Co-authored papers 4
Centre de recherche du Centre hospitalier de l'Universite de Montreal (CRCHUM)
Co-authored papers 3
Centre de recherche du Centre hospitalier universitaire de Sherbrooke
Co-authored papers 3
Centre de recherche du Centre hospitalier universitaire de Quebec-Universite Laval
Co-authored papers 2
Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Universite Laval
Co-authored papers 2
Institut de Pathologie Multisite
Co-authored papers 2
Institut du Cancer de Montreal
Co-authored papers 2
University Health Network, University of Toronto
Co-authored papers 2
Centre de recherche sur le cancer de l'Universite Laval
Co-authored papers 2
University of Toronto
Co-authored papers 2
University of California los angeles
Co-authored papers 2
CHU de Quebec-Universite Laval
Co-authored papers 2
Centre de recherche du Centre hospitalier de l'Universite de Montreal
Co-authored papers 2
University of Toronto
Co-authored papers 2
Centre de Recherche du CHU de Quebec-Universite Laval (axe Oncologie)
Co-authored papers 2
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Centre de Recherche du CHU de Quebec-Universite Laval (axe Oncologie)
Co-authored papers 2
Massachusetts General Hospital, Athinoula A. Martinos Center for Biomedical Imaging
Co-authored papers 1
The Hospital for Sick Children
Co-authored papers 1
Centre de recherche du Centre hospitalier de l'Universite de Montreal
Co-authored papers 1
Centre de recherche du Centre hospitalier de l'Universite de Montreal
Co-authored papers 1