Skip to Main Content

Author Details

Stephen L Lessnick
The Ohio State University College of Medicine
1990
113
46
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36658220The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma.Nat Cell Biol2023
36669140Randomized Phase III Trial of Ganitumab With Interval-Compressed Chemotherapy for Patients With Newly Diagnosed Metastatic Ewing Sarcoma: A Report From the Children's Oncology Group.J Clin Oncol2023
35298000Mitochondrial Dysfunction Is a Driver of SP-2509 Drug Resistance in Ewing Sarcoma.Mol Cancer Res2022
36124657EWS/FLI mediated reprogramming of 3D chromatin promotes an altered transcriptional state in Ewing sarcoma.Nucleic Acids Res2022
36221002Adverse prognostic impact of the loss of STAG2 protein expression in patients with newly diagnosed localised Ewing sarcoma: A report from the Children's Oncology Group.Br J Cancer2022
36115869An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma.NPJ Precis Oncol2022
32842875Chromatin profiling reveals relocalization of lysine-specific demethylase 1 by an oncogenic fusion protein.Epigenetics2021
33769463Patterns of Translocation Testing in Patients Enrolling in a Cooperative Group Trial for Newly Diagnosed Metastatic Ewing Sarcoma.Arch Pathol Lab Med2021
34465585Identification of a Novel <i>FUS/ETV4</i> Fusion and Comparative Analysis with Other Ewing Sarcoma Fusion Proteins.Mol Cancer Res2021
34662337Network potential identifies therapeutic miRNA cocktails in Ewing sarcoma.PLoS Comput Biol2021
32477459Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma.Oncotarget2020
33488267Survey of Paediatric Oncologists and Pathologists regarding Their Views and Experiences with Variant Translocations in Ewing and Ewing-Like Sarcoma: A Report of the Children's Oncology Group.Sarcoma2020
32658189Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis.J Vis Exp2020
32623338Identifying States of Collateral Sensitivity during the Evolution of Therapeutic Resistance in Ewing's Sarcoma.iScience2020
30685685Survival and prognosis with osteosarcoma: outcomes in more than 2000 patients in the EURAMOS-1 (European and American Osteosarcoma Study) cohort.Eur J Cancer2019
31670911Increased risk for other cancers in individuals with Ewing sarcoma and their relatives.Cancer Med2019
31553693High-Dose Chemotherapy Compared With Standard Chemotherapy and Lung Radiation in Ewing Sarcoma With Pulmonary Metastases: Results of the European Ewing Tumour Working Initiative of National Groups, 99 Trial and EWING 2008.J Clin Oncol2019
31231465Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma.Oncotarget2019
31031965Emerging novel agents for patients with advanced Ewing sarcoma: a report from the Children's Oncology Group (COG) New Agents for Ewing Sarcoma Task Force.F1000Res2019
30880335Correction: Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children's Oncology Group.Br J Cancer2019
30723142Trabectedin Inhibits EWS-FLI1 and Evicts SWI/SNF from Chromatin in a Schedule-dependent Manner.Clin Cancer Res2019
30899417Transcriptomic analysis functionally maps the intrinsically disordered domain of EWS/FLI and reveals novel transcriptional dependencies for oncogenesis.Genes Cancer2019
29059150Protein phosphatase 1 regulatory subunit 1A in ewing sarcoma tumorigenesis and metastasis.Oncogene2018
29997151Therapeutic Targeting of KDM1A/LSD1 in Ewing Sarcoma with SP-2509 Engages the Endoplasmic Reticulum Stress Response.Mol Cancer Ther2018
30131550Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children's Oncology Group.Br J Cancer2018
29950716Author Correction: EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma.Nature2018
30559927Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation.Oncotarget2018
29513652EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma.Nature2018
28847958Role for the EWS domain of EWS/FLI in binding GGAA-microsatellites required for Ewing sarcoma anchorage independent growth.Proc Natl Acad Sci U S A2017
28148901C/EBPβ-1 promotes transformation and chemoresistance in Ewing sarcoma cells.Oncotarget2017
29091716Identification of two types of GGAA-microsatellites and their roles in EWS/FLI binding and gene regulation in Ewing sarcoma.PLoS One2017
28720588EWS/FLI is a Master Regulator of Metabolic Reprogramming in Ewing Sarcoma.Mol Cancer Res2017
26848860Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targeting.Oncotarget2016
27635231Recent advances in targeted therapy for Ewing sarcoma.F1000Res2016
27297500Comparison of clinical features and outcomes in patients with extraskeletal versus skeletal localized Ewing sarcoma: A report from the Children's Oncology Group.Pediatr Blood Cancer2016
27345405Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma.Oncogene2016
27132463Current state of pediatric sarcoma biology and opportunities for future discovery: A report from the sarcoma translational research workshop.Cancer Genet2016
27569442Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial.Lancet Oncol2016
26861456Impact of Two Measures of Micrometastatic Disease on Clinical Outcomes in Patients with Newly Diagnosed Ewing Sarcoma: A Report from the Children's Oncology Group.Clin Cancer Res2016
26802024The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease.Oncotarget2016
26979396Identification of Mithramycin Analogues with Improved Targeting of the EWS-FLI1 Transcription Factor.Clin Cancer Res2016
25464386Tumoral TP53 and/or CDKN2A alterations are not reliable prognostic biomarkers in patients with localized Ewing sarcoma: a report from the Children's Oncology Group.Pediatr Blood Cancer2015
26000096EWS/FLI utilizes NKX2-2 to repress mesenchymal features of Ewing sarcoma.Genes Cancer2015
24876127Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex.Elife2014
25057021Molecular dissection of the mechanism by which EWS/FLI expression compromises actin cytoskeletal integrity and cell adhesion in Ewing sarcoma.Mol Biol Cell2014
24963049Reversible LSD1 inhibition interferes with global EWS/ETS transcriptional activity and impedes Ewing sarcoma tumor growth.Clin Cancer Res2014
25093581Clinical and biochemical function of polymorphic NR0B1 GGAA-microsatellites in Ewing sarcoma: a report from the Children's Oncology Group.PLoS One2014
25147782Targeting Glutathione S-transferase M4 in Ewing sarcoma.Front Pediatr2014
23255238Children's Oncology Group's 2013 blueprint for research: bone tumors.Pediatr Blood Cancer2013
24386509ZEB2 Represses the Epithelial Phenotype and Facilitates Metastasis in Ewing Sarcoma.Genes Cancer2013
  • 1 - 50 of 113

Recommended Authors

Wei Zhang
University of Manchester
Career Start Year 2011
Number of shared co-authors 1
Rahul K Kollipara
McDermott Center for Human Growth and Development.
Career Start Year 2010
Number of shared co-authors 1
Ana Teresa Amaral
Instituto de Salud Carlos III
Career Start Year 2009
Number of shared co-authors 14
Gaylor Boulay
Massachusetts General Hospital and Harvard Medical School
Career Start Year 2009
Number of shared co-authors 2
Bob Walker
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Career Start Year 2009
Number of shared co-authors 3
Zejuan Li
Houston Methodist Hospital
Career Start Year 2005
Number of shared co-authors 2
Ogan D Abaan
Illumina Inc.
Career Start Year 2005
Number of shared co-authors 3
Henry Yang
Cancer Science Institute of Singapore, National University of Singapore
Career Start Year 2005
Number of shared co-authors 1
Richard Koche
Memorial Sloan Kettering Cancer Center
Career Start Year 2005
Number of shared co-authors 3
Mario L Suv??
Broad Institute of MIT and Harvard
Career Start Year 2004
Number of shared co-authors 3
Aniruddha J Deshpande
Sanford Burnham Prebys Medical Discovery Institute
Career Start Year 2004
Number of shared co-authors 2
Maximilian Kauer
St. Anna Children's Cancer Research Institute (CCRI)
Career Start Year 2002
Number of shared co-authors 25
Ga??lle Pierron
Institut Curie Hospital
Career Start Year 2001
Number of shared co-authors 27
Jan Koster
Amsterdam University Medical Centers location AMC
Career Start Year 1999
Number of shared co-authors 12
Joyce E Ohm
Roswell Park Comprehensive Cancer Center
Career Start Year 1999
Number of shared co-authors 0
Andrew J Gentles
Stanford Center for Biomedical Informatics Research, Stanford University
Career Start Year 1999
Number of shared co-authors 2
Jun Yao
The University of Texas MD Anderson Cancer Center
Career Start Year 1997
Number of shared co-authors 1
Robert L Walker
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Career Start Year 1997
Number of shared co-authors 9
Brian J P Huntly
University of Cambridge
Career Start Year 1996
Number of shared co-authors 5
Stefan Fr??hling
German Cancer Research Center (DKFZ), National Center for Tumor Diseases (NCT)
Career Start Year 1996
Number of shared co-authors 13
Mar??a D Odero
University of Navarra
Career Start Year 1994
Number of shared co-authors 0
Seishi Ogawa
Kyoto University
Career Start Year 1993
Number of shared co-authors 1
Cristina E Tognon
Knight Cancer Institute, Oregon Health & Science University
Career Start Year 1993
Number of shared co-authors 7
Gunhild Jug
Children's Cancer Research Institute
Career Start Year 1991
Number of shared co-authors 6
John Easton
St Jude Children's Research Hospital
Career Start Year 1991
Number of shared co-authors 13
Scott A Armstrong
Boston Children's Hospital
Career Start Year 1990
Number of shared co-authors 8
Choh Yeung
Center for Cancer Research, National Cancer Institute
Career Start Year 1987
Number of shared co-authors 7
David M Loeb
Children's Hospital at Montefiore.
Career Start Year 1986
Number of shared co-authors 12
Ola Myklebost
Institute for Cancer Research, Oslo University Hospital
Career Start Year 1983
Number of shared co-authors 22
Alex Look
Dana-Farber Cancer Institute
Career Start Year 1975
Number of shared co-authors 11

Collaborators

Richard Gorlick
University of Texas MD Anderson Cancer Center
Co-authored papers 16
Katherine A Janeway
Co-authored papers 14
Elizabeth R Lawlor
Seattle Children's Research Institute
Co-authored papers 12
Steven G DuBois
Co-authored papers 12
Kimberly Stegmaier
Dana-Farber Cancer Institute
Co-authored papers 10
Neyssa Marina
Stanford University School of Medicine
Co-authored papers 9
Richard B Womer
Co-authored papers 9
Brian D Crompton
Co-authored papers 8
Russell Bell
Huntsman Cancer Institute at the University of Utah
Co-authored papers 7
Patrick J Grohar
Children's Hospital of Philadelphia.
Co-authored papers 7
Olivier Delattre
PSL Research University, Institut Curie Research Center, INSERM U, Institut Curie
Co-authored papers 5
Heinrich Kovar
St. Anna Children's Cancer Research Institute (CCRI), Medical University Vienna
Co-authored papers 5
Poul H Sorensen
British Columbia Cancer Research Centre
Co-authored papers 5
Douglas S Hawkins
Co-authored papers 5
Sunil Sharma
Brody School of Medicine, East Carolina University
Co-authored papers 5
Jeffrey A Toretsky
Georgetown University Medical Center, Georgetown University
Co-authored papers 5
Benjamin S Braun
Benioff Children's Hospitals, University of California san francisco
Co-authored papers 4
Donald A Barkauskas
Keck School of Medicine of the University of Southern California
Co-authored papers 4
Franck Tirode
Cancer Center of Lyon
Co-authored papers 4
Peter J Houghton
The University of Texas Health Science Center at San Antonio
Co-authored papers 3
Aaron R Thorner
Co-authored papers 3
Marc Ladanyi
Memorial Sloan Kettering Cancer Center
Co-authored papers 3
Uta Dirksen
University Hospital Essen, West German Cancer Center
Co-authored papers 3
Enrique de Alava
Servicio de Anatomia Patologica. Hospital Universitario Virgen del Rocio.
Co-authored papers 3
Jeremy Whelan
University College London Hospitals NHS Foundation Trust
Co-authored papers 3
Lee J Helman
Osteosarcoma Institute
Co-authored papers 3
Todd R Golub
Broad Institute of MIT and Harvard
Co-authored papers 3
Lynn B Jorde
University of Utah School of Medicine
Co-authored papers 3
Ching C Lau
Baylor College of Medicine
Co-authored papers 3
Katia Scotlandi
IRCCS Istituto Ortopedico Rizzoli
Co-authored papers 3
Release 1.2