Author details

Full Name

Xiaochong Wu

Affiliation

The Hospital for Sick Children

ORCID

Career Start Year

1997

Papers

H Index

Expertise

CM4AI Collaborator

Antoine Forget (CM4AI)

PMID	Paper Title	Journal Title	Published Year
36131014	Failure of human rhombic lip differentiation underlies medulloblastoma formation.	Nature	2022
36446943	Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation.	Nature	2022
34045740	Author Correction: Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma.	Nat Med	2021
33741928	The transcriptional landscape of Shh medulloblastoma.	Nat Commun	2021
32445698	Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma.	Cell	2020
30674530	<i>Sleeping Beauty</i> Insertional Mutagenesis Reveals Important Genetic Drivers of Central Nervous System Embryonal Tumors.	Cancer Res	2019
31664194	Recurrent noncoding U1Â snRNA mutations drive cryptic splicing in SHH medulloblastoma.	Nature	2019
28575493	miR miR on the wall, who's the most malignant medulloblastoma miR of them all?	Neuro Oncol	2018
29856958	A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases.	Cell	2018
30591080	A functional genomics approach to identify pathways of drug resistance in medulloblastoma.	Acta Neuropathol Commun	2018
29474906	A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases.	Cell	2018
29258295	Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling.	Nature	2018
28726821	The whole-genome landscape of medulloblastoma subtypes.	Nature	2017
28394352	Spatial heterogeneity in medulloblastoma.	Nat Genet	2017
26760213	Divergent clonal selection dominates medulloblastoma at recurrence.	Nature	2016
25391241	Foretinib is effective therapy for metastatic sonic hedgehog medulloblastoma.	Cancer Res	2015
26258683	EAG2 potassium channel with evolutionarily conserved function as a brain tumor target.	Nat Neurosci	2015
25689980	Medulloblastoma subgroups remain stable across primary and metastatic compartments.	Acta Neuropathol	2015
24493713	Cytogenetic prognostication within medulloblastoma subgroups.	J Clin Oncol	2014
25490452	SnapShot: Medulloblastoma.	Cancer Cell	2014
25059231	Genetic drivers of metastatic dissemination in sonic hedgehog medulloblastoma.	Acta Neuropathol Commun	2014
25150496	The G protein Î± subunit GÎ±s is a tumor suppressor in Sonic hedgehog-driven medulloblastoma.	Nat Med	2014
24553142	Epigenomic alterations define lethal CIMP-positive ependymomas of infancy.	Nature	2014
23706743	The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation.	Cell	2013
24092238	MyoD is a tumor suppressor gene in medulloblastoma.	Cancer Res	2013
24174164	TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.	Acta Neuropathol	2013
22343890	Clonal selection drives genetic divergence of metastatic medulloblastoma.	Nature	2012
22832581	Subgroup-specific structural variation across 1,000 medulloblastoma genomes.	Nature	2012
22875024	Functional genomics identifies drivers of medulloblastoma dissemination.	Cancer Res	2012
21718590	Mouse models of medulloblastoma.	Chin J Cancer	2011
21691921	FGFR3-expressing smooth muscle-like stromal cells differentiate in response to FGFR2IIIb-expressing prostate tumor cells and delay tumor progression.	In Vitro Cell Dev Biol Anim	2011
19270706	Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma.	Nat Genet	2009
18465753	p21 activated kinase 5 activates Raf-1 and targets it to mitochondria.	J Cell Biochem	2008
17064668	Multiple Rho proteins regulate the subcellular targeting of PAK5.	Biochem Biophys Res Commun	2006
15710605	B-Raf and Raf-1 are regulated by distinct autoregulatory mechanisms.	J Biol Chem	2005
15611121	Characterization of the biochemical and transforming properties of the neuroepithelial transforming protein 1.	J Biol Chem	2005
15231666	Directionally specific paracrine communication mediated by epithelial FGF9 to stromal FGFR3 in two-compartment premalignant prostate tumors.	Cancer Res	2004
12941818	Stromal cell heterogeneity in fibroblast growth factor-mediated stromal-epithelial cell cross-talk in premalignant prostate tumors.	Cancer Res	2003
12466116	Increased carbon tetrachloride-induced liver injury and fibrosis in FGFR4-deficient mice.	Am J Pathol	2002
11431373	A rare premalignant prostate tumor epithelial cell syndecan-1 forms a fibroblast growth factor-binding complex with progression-promoting ectopic fibroblast growth factor receptor 1.	Cancer Res	2001
11710433	Directional specificity of prostate stromal to epithelial cell communication via FGF7/FGFR2 is set by cell- and FGFR2 isoform-specific heparan sulfate.	In Vitro Cell Dev Biol Anim	2001
10419453	Requirement for anticoagulant heparan sulfate in the fibroblast growth factor receptor complex.	J Biol Chem	1999
10336501	Specificity for fibroblast growth factors determined by heparan sulfate in a binary complex with the receptor kinase.	J Biol Chem	1999
9466672	High salt inhibits both heparin-dependent and heparin-independent complexes of fibroblast growth factor and the receptor kinase.	In Vitro Cell Dev Biol Anim	1997

1 - 44 of 44

Harish N Vasudevan

University of California San Francisco

Career Start Year 2005

Number of shared co-authors 10

Haotian Zhao

New York Institute of Technology College of Osteopathic Medicine

Career Start Year 2004

Number of shared co-authors 10

Bo Hu

Northwestern University Feinberg School of Medicine

Career Start Year 2003

Number of shared co-authors 2

Massimo Squatrito

Seve Ballesteros Foundation Brain Tumor group

Career Start Year 2002

Number of shared co-authors 6

Agnieszka Bronisz

Mossakowski Medical Research Institute, Polish Academy of Sciences

Career Start Year 1999

Number of shared co-authors 1

Shwetal Mehta

Barrow Neurological Institute, St. Joseph's Hospital and Medical Center

Career Start Year 1998

Number of shared co-authors 2

Robert L Walker

Center for Cancer Research, National Cancer Institute, National Institutes of Health

Career Start Year 1997

Number of shared co-authors 1

Shi-Yuan Cheng

Northwestern University Feinberg School of Medicine

Career Start Year 1996

Number of shared co-authors 2

Christopher Ryan Miller

University of Illinois at Urbana-Champaign

Career Start Year 1996

Number of shared co-authors 22

Michael A White

University of Georgia

Career Start Year 1994

Number of shared co-authors 1

Sanja Pajovic

Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children

Career Start Year 1993

Number of shared co-authors 18

Frank B Furnari

University of California San Diego

Career Start Year 1992

Number of shared co-authors 10

John Easton

St Jude Children's Research Hospital

Career Start Year 1991

Number of shared co-authors 29

Aykut Uren

Georgetown University Medical Center

Career Start Year 1991

Number of shared co-authors 5

Oliver B??gler

American Association for Cancer Research, Henry Ford Hospital, Ludwig Institute for Cancer Research, National Cancer Institute, Salk Institute for Biological Studies, University of Cambridge, University of Texas MD Anderson Cancer Center, Virginia Commonwealth University

Career Start Year 1990

Number of shared co-authors 1

E Alejandro Sweet-Cordero

University of California San Francisco

Career Start Year 1989

Number of shared co-authors 10

Antonio Iavarone

Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami

Career Start Year 1989

Number of shared co-authors 31

Christopher M Hovens

Royal Melbourne Hospital, The University of Melbourne

Career Start Year 1989

Number of shared co-authors 6

Dirk Geerts

Amsterdam University Medical Center

Career Start Year 1989

Number of shared co-authors 2

Wei Zhang

The University of Texas MD Anderson Cancer Center

Career Start Year 1988

Number of shared co-authors 11

James F Amatruda

Children's Hospital of Los Angeles

Career Start Year 1988

Number of shared co-authors 4

William C Hahn

Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute

Career Start Year 1987

Number of shared co-authors 15

Jorge Silvio Gutkind

Moores Cancer Center, University of California San Diego

Career Start Year 1984

Number of shared co-authors 3

Ching C Lau

Baylor College of Medicine

Career Start Year 1982

Number of shared co-authors 47

Charles Keller

Children's Cancer Therapy Development Institute

Career Start Year 1980

Number of shared co-authors 5

David J Adams

Wellcome Sanger Institute

Career Start Year 1980

Number of shared co-authors 9

Francisca Vazquez

Broad Institute of MIT and Harvard

Career Start Year 1979

Number of shared co-authors 6

Michael C Ostrowski

Hollings Cancer Center, Medical University of South Carolina

Career Start Year 1979

Number of shared co-authors 2

Webster K Cavenee

Ludwig Institute for Cancer Research, University of California San Diego

Career Start Year 1977

Number of shared co-authors 12

Frank McCormick

Frederick National Laboratory for Cancer Research

Career Start Year 1975

Number of shared co-authors 5

row(s) 1 - 30 of 30

Michael D Taylor

The Hospital for Sick Children

Co-authored papers 31

Vijay Ramaswamy

Hospital for Sick Children

Co-authored papers 21

Livia Garzia

The Research Institute of the McGill University Health Centre, McGill University

Co-authored papers 20

Betty Luu

University of Wollongong

Co-authored papers 16

Paul A Northcott

St Jude Children's Research Hospital

Co-authored papers 16

Nada Jabado

McGill University Health Centre (MUHC), Montreal Children's Hospital (MCH)

Co-authored papers 16

Stefan M Pfister

Hopp Children's Cancer Center Heidelberg (KiTZ)

Co-authored papers 16

Florence M G Cavalli

Institut Curie, PSL Research University

Co-authored papers 14

Adrian M Dubuc

Dana-Farber Cancer Institute

Co-authored papers 14

Stephen C Mack

St Jude Children's Research Hospital

Co-authored papers 14

William A Weiss

University of California san francisco

Co-authored papers 13

Charles G Eberhart

Wilmer Eye Institute, Johns Hopkins Medical Institutions

Co-authored papers 13

Anca Sorana Morrissy

Cumming School of Medicine, University of Calgary

Co-authored papers 13

Peter B Dirks

The Hospital for Sick Children, University of Toronto

Co-authored papers 12

Xin Wang

The Chinese University of Hong Kong, Prince of Wales Hospital

Co-authored papers 12

Eric Bouffet

The Hospital for Sick Children

Co-authored papers 12

Robert J Wechsler-Reya

Sanford Burnham Prebys Medical Discovery Institute

Co-authored papers 12

Marc Remke

and Clinical Immunology, Heinrich Heine University, University Hospital Dusseldorf

Co-authored papers 12

Andrey Korshunov

Institute of Pathology, University Hospital Heidelberg

Co-authored papers 12

Claudia C Faria

Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN)

Co-authored papers 12

James T Rutka

Hospital for Sick Children

Co-authored papers 11

David J H Shih

University of Texas MD Anderson Cancer Center Houston

Co-authored papers 11

Marco A Marra

University of British Columbia

Co-authored papers 11

Marcel Kool

Hopp Children's Cancer Center (KiTZ)

Co-authored papers 11

Cynthia Hawkins

The Hospital for Sick Children

Co-authored papers 10

David Malkin

Hospital for Sick Children

Co-authored papers 10

Uri Tabori

Co-authored papers 10

Toshihiro Kumabe

Kitasato University School of Medicine

Co-authored papers 9

Hamza Farooq

BioBox Analytics Inc.

Co-authored papers 9

Steven J M Jones

University of British Columbia

Co-authored papers 9

1 - 30

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