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Author Details

Gordon V Louie
The Howard Hughes Medical Institute, Salk Institute for Biological Studies
1985
41
30
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37813856Biochemistry and Protein Interactions of the CYREN Microprotein.Biochemistry2023
37829009Masked cerulenin enables a dual-site selective protein crosslink.Chem Sci2023
37503021Overcoming Resolution Attenuation During Tilted Cryo-EM Data Collection.bioRxiv2023
32284603Modulation of auxin formation by the cytosolic phenylalanine biosynthetic pathway.Nat Chem Biol2020
31268677Substrate Specificity and Engineering of Mevalonate 5-Phosphate Decarboxylase.ACS Chem Biol2019
27001835Biosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase-thioesterase enzyme pair.Proc Natl Acad Sci U S A2016
27328867Biosynthetic potential of sesquiterpene synthases: product profiles of Egyptian Henbane premnaspirodiene synthase and related mutants.J Antibiot (Tokyo)2016
24615769Genetically encoding photoswitchable click amino acids in Escherichia coli and mammalian cells.Angew Chem Int Ed Engl2014
25217505Structural studies of cinnamoyl-CoA reductase and cinnamyl-alcohol dehydrogenase, key enzymes of monolignol biosynthesis.Plant Cell2014
24019075Expanding the library and substrate diversity of the pyrrolysyl-tRNA synthetase to incorporate unnatural amino acids containing conjugated rings.Chembiochem2013
24162851Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement.Nature2013
22622584Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis.Nature2012
22850796Architectures, mechanisms and molecular evolution of natural product methyltransferases.Nat Prod Rep2012
21681861Genetically encoding unnatural amino acids in neural stem cells and optically reporting voltage-sensitive domain changes in differentiated neurons.Stem Cells2011
20952635Functional analyses of caffeic acid O-Methyltransferase and Cinnamoyl-CoA-reductase genes from perennial ryegrass (Lolium perenne).Plant Cell2010
21177481Structure-function analyses of a caffeic acid O-methyltransferase from perennial ryegrass reveal the molecular basis for substrate preference.Plant Cell2010
18208524The multiple phenylpropene synthases in both Clarkia breweri and Petunia hybrida represent two distinct protein lineages.Plant J2008
17240984Discovery of two cyanobacterial phenylalanine ammonia lyases: kinetic and structural characterization.Biochemistry2007
17912370Structure and reaction mechanism of basil eugenol synthase.PLoS One2007
17603477Genetically encoding unnatural amino acids for cellular and neuronal studies.Nat Neurosci2007
17185228Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases.Chem Biol2006
16021622Structural analysis of a set of proteins resulting from a bacterial genomics project.Proteins2005
16511038Structure of the pseudouridine synthase RsuA from Haemophilus influenzae.Acta Crystallogr Sect F Struct Biol Cryst Commun2005
9659904Crystal structure of the complex of diphtheria toxin with an extracellular fragment of its receptor.Mol Cell1997
8727319The three-dimensional structure of Escherichia coli porphobilinogen deaminase at 1.76-A resolution.Proteins1996
7819192Structural studies of the roles of residues 82 and 85 at the interactive face of cytochrome c.Biochemistry1995
7842864Structural studies on porphobilinogen deaminase.Ciba Found Symp1994
8081367Identification of five novel mutations in the porphobilinogen deaminase gene.Hum Mol Genet1994
7849582The three-dimensional structures of mutants of porphobilinogen deaminase: toward an understanding of the structural basis of acute intermittent porphyria.Protein Sci1994
8224474Molecular recognition in protein families: a database of aligned three-dimensional structures of related proteins.Biochem Soc Trans1993
8262523Detection of a high mutation frequency in exon 12 of the porphobilinogen deaminase gene in patients with acute intermittent porphyria.Hum Genet1993
8436121Purification, characterization, crystallisation and X-ray analysis of selenomethionine-labelled hydroxymethylbilane synthase from Escherichia coli.Eur J Biochem1993
1522882Structure of porphobilinogen deaminase reveals a flexible multidomain polymerase with a single catalytic site.Nature1992
1548705Crystallization and preliminary X-ray investigation of Escherichia coli porphobilinogen deaminase.J Mol Biol1992
2166169High-resolution refinement of yeast iso-1-cytochrome c and comparisons with other eukaryotic cytochromes c.J Mol Biol1990
2166170High-resolution three-dimensional structure of horse heart cytochrome c.J Mol Biol1990
2557455A polypeptide chain-refolding event occurs in the Gly82 variant of yeast iso-1-cytochrome c.J Mol Biol1989
2494175A moderate form of hemophilia B is caused by a novel mutation in the protease domain of factor IXVancouver.J Biol Chem1989
2832611Yeast iso-1-cytochrome c. A 2.8 A resolution three-dimensional structure determination.J Mol Biol1988
2849996Role of phenylalanine-82 in yeast iso-1-cytochrome c and remote conformational changes induced by a serine residue at this position.Biochemistry1988
3877053Characterization of human blood coagulation factor XII cDNA. Prediction of the primary structure of factor XII and the tertiary structure of beta-factor XIIa.J Biol Chem1985
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Collaborators

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Albert Einstein College of Medicine
Co-authored papers 2
Duncan Guthrie Institute of Medical Genetics
Co-authored papers 2
The State University of New Jersey
Co-authored papers 1
University of California
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Co-authored papers 1
Friedman Brain Institute, Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Howard Hughes Medical Institute, University of Washington
Co-authored papers 1
Stanford University
Co-authored papers 1
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Eli Lilly and Co.
Co-authored papers 1
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Genentech Inc.
Co-authored papers 1
Indian Institute of Science
Co-authored papers 1
Foundation for Applied Molecular Evolution
Co-authored papers 1
NYU Langone Hospital - Brooklyn Brooklyn
Co-authored papers 1
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Co-authored papers 1
Institute of Cardiovascular Science, University College London
Co-authored papers 1
Joint Center for Biosciences
Co-authored papers 1
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Abo Akademi University
Co-authored papers 1