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Author Details

K F Austen
Brigham & Women's Hospital
1959
748
145
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
34644258The Discovery of Discrete Developmental Pathways Directing Constitutive and Induced Mast Cells in Mice.J Immunol2021
33753496The CysLT<sub>2</sub>R receptor mediates leukotriene C<sub>4</sub>-driven acute and chronic itch.Proc Natl Acad Sci U S A2021
33745886Proceedings from the Inaugural American Initiative in Mast Cell Diseases (AIM) Investigator Conference.J Allergy Clin Immunol2021
32929378Mast cells as a unique hematopoietic lineage and cell system: From Paul Ehrlich's visions to precision medicine concepts.Theranostics2020
30559191Cysteinyl leukotriene 2 receptor promotes endothelial permeability, tumor angiogenesis, and metastasis.Proc Natl Acad Sci U S A2019
31296303Roles of cysteinyl leukotrienes and their receptors in immune cell-related functions.Adv Immunol2019
31476322AAAAI Mast Cell Disorders Committee Work Group Report: Mast cell activation syndrome (MCAS) diagnosis and management.J Allergy Clin Immunol2019
31027995Mechanical Skin Injury Promotes Food Anaphylaxis by Driving Intestinal Mast Cell Expansion.Immunity2019
29382599Mentoring: An art and a responsibility.J Allergy Clin Immunol2018
28011865Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s.J Exp Med2017
28254862Advances in the Classification and Treatment of Mastocytosis: Current Status and Outlook toward the Future.Cancer Res2017
29051149Resolution of a human mast cell development conundrum.Blood2017
27185938Leukotriene E4 elicits respiratory epithelial cell mucin release through the G-protein-coupled receptor, GPR99.Proc Natl Acad Sci U S A2016
27226094CysLT1 Receptor Is Protective against Oxidative Stress in a Model of Irritant-Induced Asthma.J Immunol2016
27135604Expression profiling of constitutive mast cells reveals a unique identity within the immune system.Nat Immunol2016
25291985Maturation of mast cell progenitors to mucosal mast cells during allergic pulmonary inflammation in mice.Mucosal Immunol2015
26488812Licensed to Ill: IL-9 Generation in Immature Mast Cells Permits Food-Elicited Anaphylaxis.Immunity2015
24453247Dectin-2 regulates the effector phase of house dust mite-elicited pulmonary inflammation independently from its role in sensitization.J Immunol2014
24928991B cells regulate CD4+ T cell responses to papain following B cell receptor-independent papain uptake.J Immunol2014
24925415K. Frank Austen. Boston, Mass., USA.Chem Immunol Allergy2014
24523504Mouse mast cell proteases 4 and 5 mediate epidermal injury through disruption of tight junctions.J Immunol2014
23374269Epicutaneous sensitization results in IgE-dependent intestinal mast cell expansion and food-induced anaphylaxis.J Allergy Clin Immunol2013
23504326Identification of GPR99 protein as a potential third cysteinyl leukotriene receptor with a preference for leukotriene E4 ligand.J Biol Chem2013
23319739Mast cells recruited to mesenteric lymph nodes during helminth infection remain hypogranular and produce IL-4 and IL-6.J Immunol2013
22416124Eosinophil-derived leukotriene C4 signals via type 2 cysteinyl leukotriene receptor to promote skin fibrosis in a mouse model of atopic dermatitis.Proc Natl Acad Sci U S A2012
23002438Cysteinyl leukotriene 2 receptor on dendritic cells negatively regulates ligand-dependent allergic pulmonary inflammation.J Immunol2012
22840841Developmental origin and functional specialization of mast cell subsets.Immunity2012
21454538The catalytic architecture of leukotriene C4 synthase with two arginine residues.J Biol Chem2011
22118523Mast cell deficiency, a game of kit and mouse.Immunity2011
21825171Protease phenotype of constitutive connective tissue and of induced mucosal mast cells in mice is regulated by the tissue.Proc Natl Acad Sci U S A2011
21934409Cysteinyl leukotrienes impair hypoxic pulmonary vasoconstriction in endotoxemic mice.Anesthesiology2011
21357742Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes.J Exp Med2011
20427772The role of the CCL2/CCR2 axis in mouse mast cell migration in vitro and in vivo.J Immunol2010
21076070The inflammatory response after an epidermal burn depends on the activities of mouse mast cell proteases 4 and 5.J Immunol2010
20574000GPR17 regulates immune pulmonary inflammation induced by house dust mites.J Immunol2010
20601599T regulatory cells control antigen-induced recruitment of mast cell progenitors to the lungs of C57BL/6 mice.J Immunol2010
19124755Dectin-2 recognition of house dust mite triggers cysteinyl leukotriene generation by dendritic cells.J Immunol2009
19647860The leukotriene E4 puzzle: finding the missing pieces and revealing the pathobiologic implications.J Allergy Clin Immunol2009
19766085Innate cells and T helper 2 cell immunity in airway inflammation.Immunity2009
19783672Antigen-induced increases in pulmonary mast cell progenitor numbers depend on IL-9 and CD1d-restricted NKT cells.J Immunol2009
19561298GPR17 is a negative regulator of the cysteinyl leukotriene 1 receptor response to leukotriene D4.Proc Natl Acad Sci U S A2009
17877459Doing what I like.Annu Rev Immunol2008
18931305Functional recognition of a distinct receptor preferential for leukotriene E4 in mice lacking the cysteinyl leukotriene 1 and 2 receptors.Proc Natl Acad Sci U S A2008
19052120Outbreak of adverse reactions associated with contaminated heparin.N Engl J Med2008
18204420The cysteinyl leukotrienes: where do they come from? What are they? Where are they going?Nat Immunol2008
18434646Contaminated heparin associated with adverse clinical events and activation of the contact system.N Engl J Med2008
17141857The National Institute of Allergy and Infectious Diseases' Asthma and Allergic Disease Centers: a personal commentary.J Allergy Clin Immunol2007
17998392Mast cell deficiency in Kit(W-sh) mice does not impair antibody-mediated arthritis.J Exp Med2007
18077323Pulmonary CXCR2 regulates VCAM-1 and antigen-induced recruitment of mast cell progenitors.Proc Natl Acad Sci U S A2007
17632548Crystal structure of a human membrane protein involved in cysteinyl leukotriene biosynthesis.Nature2007
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Collaborators

Richard L Stevens
School of Biomedical Sciences and Pharmacy, University of Newcastle
Co-authored papers 89
Michael F Gurish
Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 41
Daniel S Friend
Harvard Medical School
Co-authored papers 37
William F Owen
Co-authored papers 19
Namit Ghildyal
Harvard Medical School
Co-authored papers 17
Marc E Rothenberg
Cincinnati Children's Hospital Medical Center
Co-authored papers 10
Jonathan S Coblyn
Co-authored papers 7
Michael E Weinblatt
Co-authored papers 6
Ryoji Matsumoto
Atopy Research Center, Juntendo University Graduate School of Medicine
Co-authored papers 5
John E Hunt
Harvard Medical School
Co-authored papers 5
Steven A Krilis
University of NSW
Co-authored papers 5
Robert C Murphy
Co-authored papers 3
Jerome Ritz
Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital
Co-authored papers 3
Dennis J Hoover
Synaptic Dynamics Inc.
Co-authored papers 3
Jason Gotlib
Stanford University School of Medicine
Co-authored papers 3
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 2
Chifu Huang
Brigham and Women's Hospital and Harvard Medical School
Co-authored papers 2
Stephen U Stechschulte
worked together in the Northwest Haiti an Mission Hospital.
Co-authored papers 2
Robert Langer
Co-authored papers 2
Melody C Carter
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 2
David M Lee
Co-authored papers 2
Anne Y Liu
Co-authored papers 2
Eugene Braunwald
Co-authored papers 1
Joseph V Bonventre
Brigham & Women's Hospital
Co-authored papers 1
Jean Michon
Institut Curie
Co-authored papers 1
Sunil K Joshi
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Shinsuke Yasuda
Tokyo Medical and Dental University
Co-authored papers 1
Joseph H Nadeau
Co-authored papers 1
Stuart H Orkin
Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School
Co-authored papers 1
Robert M Stroud
University of California San Francisco
Co-authored papers 1
Release 1.2