Author details

Full Name

High Seng Chai

Affiliation

Mayo Clinic

ORCID

Career Start Year

2007

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
28222112	Genome-wide study of resistant hypertension identified from electronic health records.	PLoS One	2017
27727239	Human whole genome genotype and transcriptome data for Alzheimer's and other neurodegenerative diseases.	Sci Data	2016
27066552	Late-onset Alzheimer disease risk variants mark brain regulatory loci.	Neurol Genet	2015
25129075	Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.	Nat Neurosci	2014
25324900	Association of MAPT haplotypes with Alzheimer's disease risk and MAPT brain gene expression levels.	Alzheimers Res Ther	2014
23362515	Response to genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.	Hypertension	2013
24083646	Elevated cardiac troponin T levels in critically ill patients with sepsis.	Am J Med	2013
24223926	An integrated model of the transcriptome of HER2-positive breast cancer.	PLoS One	2013
22088845	TREAT: a bioinformatics tool for variant annotations and visualizations in targeted and exome sequencing data.	Bioinformatics	2012
22722634	Novel late-onset Alzheimer disease loci variants associate with brain gene expression.	Neurology	2012
22685416	Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants.	PLoS Genet	2012
22494505	Glutathione S-transferase omega genes in Alzheimer and Parkinson disease risk, age-at-diagnosis and brain gene expression: an association study with mechanistic implications.	Mol Neurodegener	2012
22655260	Deep Sequence Analysis of Non-Small Cell Lung Cancer: Integrated Analysis of Gene Expression, Alternative Splicing, and Single Nucleotide Variations in Lung Adenocarcinomas with and without Oncogenic KRAS Mutations.	Front Oncol	2012
22566498	Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.	Hypertension	2012
22249968	Impact of data fragmentation across healthcare centers on the accuracy of a high-throughput clinical phenotyping algorithm for specifying subjects with type 2 diabetes mellitus.	J Am Med Inform Assoc	2012
22415876	Concordance of changes in metabolic pathways based on plasma metabolomics and skeletal muscle transcriptomics in type 1 diabetes.	Diabetes	2012
22386179	Germline predictors of androgen deprivation therapy response in advanced prostate cancer.	Mayo Clin Proc	2012
21646302	Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.	Mayo Clin Proc	2011
22033252	Association of TNFSF8 polymorphisms with peripheral neutrophil count.	Mayo Clin Proc	2011
22171553	Batch effect correction for genome-wide methylation data with Illumina Infinium platform.	BMC Med Genomics	2011
21965549	Homozygosity mapping and exome sequencing reveal GATAD1 mutation in autosomal recessive dilated cardiomyopathy.	Circ Cardiovasc Genet	2011
21981779	Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies.	Am J Hum Genet	2011
21622959	A novel bioinformatics pipeline for identification and characterization of fusion transcripts in breast cancer and normal cell lines.	Nucleic Acids Res	2011
20587065	Spatial normalization improves the quality of genotype calling for Affymetrix SNP 6.0 arrays.	BMC Bioinformatics	2010
21035593	Significance of elevated cardiac troponin T levels in critically ill patients with acute respiratory disease.	Am J Med	2010
20525348	Copy number variation and cytidine analogue cytotoxicity: a genome-wide association approach.	BMC Genomics	2010
19050617	Long-term prognostic significance of elevated cardiac troponin levels in critically ill patients with acute gastrointestinal bleeding.	Crit Care Med	2009
19752840	Efficacy of omega-3 fatty acids in mood disorders - a systematic review and metaanalysis.	Psychopharmacol Bull	2009
19344520	GLOSSI: a method to assess the association of genetic loci-sets with complex diseases.	BMC Bioinformatics	2009
18186536	Use of log-skew-normal distribution in analysis of continuous data with a discrete component at zero.	Stat Med	2008
18591461	Genomic association analysis suggests chromosome 12 locus influencing antihypertensive response to thiazide diuretic.	Hypertension	2008
18209672	Elevated cardiac troponin is an independent risk factor for short- and long-term mortality in medical intensive care unit patients.	Crit Care Med	2008
16730015	Measures of arterial stiffness and wave reflection are associated with walking distance in patients with peripheral arterial disease.	Atherosclerosis	2007

1 - 33 of 33

Nicholas B Larson

Mayo Clinic

Career Start Year 2012

Number of shared co-authors 22

Daryl Waggott

Ontario Institute for Cancer Research

Career Start Year 2009

Number of shared co-authors 8

Alexander Teumer

University Medicine Greifswald

Career Start Year 2008

Number of shared co-authors 39

Stephanie Hesselson

Victor Chang Cardiac Research Institute

Career Start Year 2007

Number of shared co-authors 4

Ian B Stanaway

Kidney Research Institute and Division of Nephrology, University of Washington

Career Start Year 2006

Number of shared co-authors 29

William S Bush

Cleveland Institute for Computational Biology, Case Western Reserve University

Career Start Year 2006

Number of shared co-authors 90

Christian M Shaffer

Vanderbilt University

Career Start Year 2004

Number of shared co-authors 36

Zolt??n Kutalik

University of Lausanne

Career Start Year 2004

Number of shared co-authors 22

Brendan J Keating

Perelman School of Medicine, University of Pennsylvania

Career Start Year 2003

Number of shared co-authors 39

Martina M??ller-Nurasyid

Institute for Medical Information Processing

Career Start Year 2003

Number of shared co-authors 29

Sek Won Kong

Boston Children's Hospital, Seoul National University, Seoul National University Hospital

Career Start Year 2003

Number of shared co-authors 1

Andrew D Johnson

and Blood Institute

Career Start Year 2001

Number of shared co-authors 53

Gregory D Jenkins

Mayo Clinic

Career Start Year 2001

Number of shared co-authors 39

Chunyu Liu

Boston University School of Public Health

Career Start Year 2001

Number of shared co-authors 20

Ilja M Nolte

University of Groningen, University Medical Center Groningen

Career Start Year 2000

Number of shared co-authors 26

David R Crosslin

University of Washington Medical Center

Career Start Year 2000

Number of shared co-authors 54

Christian Gieger

German Research Center for Cardiovascular Disease (DZHK)

Career Start Year 1999

Number of shared co-authors 30

Nicole Soranzo

Wellcome Sanger Institute

Career Start Year 1998

Number of shared co-authors 18

Yi-Ju Li

Duke University School of Medicine

Career Start Year 1998

Number of shared co-authors 3

Eric E Schadt

Icahn School of Medicine at Mount Sinai

Career Start Year 1998

Number of shared co-authors 52

Ulrich Broeckel

Medical College of Wisconsin

Career Start Year 1998

Number of shared co-authors 16

Grier P Page

Genomics and Translational Research Center

Career Start Year 1996

Number of shared co-authors 4

Hemant K Tiwari

University of Alabama at Birmingham

Career Start Year 1995

Number of shared co-authors 24

Jonathan D Mosley

Vanderbilt University Medical Center

Career Start Year 1995

Number of shared co-authors 37

Panos Deloukas

William Harvey Research Institute, Queen Mary University of London

Career Start Year 1992

Number of shared co-authors 89

Elizabeth R Hauser

Duke University School of Medicine

Career Start Year 1989

Number of shared co-authors 10

Peter Kraft

Harvard T. H. Chan School of Public Health

Career Start Year 1988

Number of shared co-authors 33

Daniel I Chasman

Harvard Medical School, Harvard University

Career Start Year 1987

Number of shared co-authors 54

Nicholas J Schork

University of California San Diego

Career Start Year 1987

Number of shared co-authors 51

Albert V Smith

University of Michigan School of Public Health ann arbor

Career Start Year 1987

Number of shared co-authors 99

row(s) 1 - 30 of 30

Jean-Pierre A Kocher

Mayo Clinic

Co-authored papers 10

Yan W Asmann

Mayo Clinic

Co-authored papers 8

Curtis S Younkin

Mayo Clinic

Co-authored papers 8

Nil??fer Ertekin-Taner

Mayo Clinic

Co-authored papers 7

Steven G Younkin

Mayo Clinic

Co-authored papers 7

Fanggeng Zou

Cincinnati Children's Hospital Medical Center

Co-authored papers 7

Julia E Crook

Center for Clinical and Translational Science, Mayo Clinic

Co-authored papers 6

Ronald C Petersen

Mayo Clinic Rochester

Co-authored papers 6

Dennis W Dickson

Mayo Clinic Jacksonville

Co-authored papers 6

Kimberly G Malphrus

Mayo Clinic Florida

Co-authored papers 6

Asha A Nair

Mayo Clinic

Co-authored papers 6

Kent R Bailey

Mayo Clinic

Co-authored papers 6

Minerva M Carrasquillo

Mayo Clinic

Co-authored papers 6

Thuy Nguyen

Mayo Clinic

Co-authored papers 6

Mariet Allen

Mayo Clinic

Co-authored papers 6

Neill R Graff-Radford

Mayo Clinic Florida

Co-authored papers 6

Mariza de Andrade

Mayo Clinic

Co-authored papers 5

Gina Bisceglio

Mayo Clinic

Co-authored papers 5

Sarah J Lincoln

Mayo Clinic

Co-authored papers 5

Bekele Afessa

Mayo Clinic

Co-authored papers 4

Suzette J Bielinski

Mayo Clinic

Co-authored papers 4

Christopher G Chute

Brown University, Brown University Warren Alpert Medical School, Dartmouth-Hitchcock Medical Center, Harvard School of Public Health, Johns Hopkins Medicine, Mayo Clinic Minnesota

Co-authored papers 4

Iftikhar J Kullo

Mayo Clinic

Co-authored papers 4

Eric B Larson

University of Washington

Co-authored papers 3

Margaret A Pericak-Vance

Co-authored papers 3

Gail P Jarvik

University of Washington Medical Center

Co-authored papers 3