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Author Details

Tomohiro Sawa
Kumamoto University
1992
190
46
PMIDPaper TitleJournal TitlePublished Year
37294201Redox Regulation of Xenobiotics by Reactive Sulfur and Supersulfide Species.Antioxid Redox Signal2024
36920987<i>Helicobacter kumamotonensis</i> sp. nov., isolated from human clinical specimens.Int J Syst Evol Microbiol2023
37965540Alkyl gallates inhibit serine <i>O</i>-acetyltransferase in bacteria and enhance susceptibility of drug-resistant Gram-negative bacteria to antibiotics.Front Microbiol2023
37491435Supersulphides provide airway protection in viral and chronic lung diseases.Nat Commun2023
37536084Sulfur metabolic response in macrophage limits excessive inflammatory response by creating a negative feedback loop.Redox Biol2023
37872133Supersulfide biology and translational medicine for disease control.Br J Pharmacol2023
37373128Cystathionine γ-Lyase Self-Inactivates by Polysulfidation during Cystine Metabolism.Int J Mol Sci2023
36972339Modification of Silver Nanoplates with Cell-Binding Subunit of Bacterial Toxin and Their Antimicrobial Activity against Intracellular Bacteria.ACS Appl Bio Mater2023
34409860Chemical Biology of Reactive Sulfur Species: Hydrolysis-Driven Equilibrium of Polysulfides as a Determinant of Physiological Functions.Antioxid Redox Signal2022
35807998Controlled Delivery of an Anti-Inflammatory Toxin to Macrophages by Mutagenesis and Nanoparticle Modification.Nanomaterials (Basel)2022
35345462Subtilase cytotoxin from Shiga-toxigenic <i>Escherichia coli</i> impairs the inflammasome and exacerbates enteropathogenic bacterial infection.iScience2022
35420440Movements of Ancient Human Endogenous Retroviruses Detected in SOX2-Expressing Cells.J Virol2022
36480740Structural Determination of the Nanocomplex of Borate with Styrene-Maleic Acid Copolymer-Conjugated Glucosamine Used as a Multifunctional Anticancer Drug.ACS Appl Bio Mater2022
36556185Enhanced Permeability and Retention Effect as a Ubiquitous and Epoch-Making Phenomenon for the Selective Drug Targeting of Solid Tumors.J Pers Med2022
36136589Iron accelerates Fusobacterium nucleatum-induced CCL8 expression in macrophages and is associated with colorectal cancer progression.JCI Insight2022
36201318Non-canonical inflammasome activation analysis in a mouse model of Citrobacter rodentium infection.STAR Protoc2022
34981119New insights into the regulatory roles of glutathione in NLRP3-inflammasome-mediated immune and inflammatory responses.J Biochem2022
35033681Regulation of nitric oxide/reactive oxygen species redox signaling by nNOS splicing variants.Nitric Oxide2022
35033591Fusobacterium nucleatum promotes esophageal squamous cell carcinoma progression via the NOD1/RIPK2/NF-κB pathway.Cancer Lett2022
35049500What triggers inflammation in COVID-19?Elife2022
33299132Fusobacterium nucleatum confers chemoresistance by modulating autophagy in oesophageal squamous cell carcinoma.Br J Cancer2021
33740502ATP exposure stimulates glutathione efflux as a necessary switch for NLRP3 inflammasome activation.Redox Biol2021
33536706Antioxidative and anti-inflammatory actions of reactive cysteine persulfides.J Clin Biochem Nutr2021
33536705Introduction to serial reviews: Recent developments in research of reactive sulfur species.J Clin Biochem Nutr2021
33781062Cysteine Hydropersulfide Inactivates β-Lactam Antibiotics with Formation of Ring-Opened Carbothioic S-Acids in Bacteria.ACS Chem Biol2021
34251710Development of potent antipseudomonal β-lactams by means of polycarboxylation of aminopenicillins.Microbiol Immunol2021
34071552EPR-Effect Enhancers Strongly Potentiate Tumor-Targeted Delivery of Nanomedicines to Advanced Cancers: Further Extension to Enhancement of the Therapeutic Effect.J Pers Med2021
33450582Polymer-conjugated glucosamine complexed with boric acid shows tumor-selective accumulation and simultaneous inhibition of glycolysis.Biomaterials2021
32295903Existence of Replication-Competent Minor Variants with Different Coreceptor Usage in Plasma from HIV-1-Infected Individuals.J Virol2020
32636924The Prevalence and Diagnostic Ratio of Familial Hypercholesterolemia (FH) and Proportion of Acute Coronary Syndrome in Japanese FH Patients in a Healthcare Record Database Study.Cardiovasc Ther2020
32594350Effect of color information on the diagnostic performance of glaucoma in deep learning using few fundus images.Int Ophthalmol2020
32867265Enzymatic Regulation and Biological Functions of Reactive Cysteine Persulfides and Polysulfides.Biomolecules2020
32184018Involvement of protein disulfide isomerase in subtilase cytotoxin-induced cell death in HeLa cells.Biochem Biophys Res Commun2020
32502899Astrocyte glutathione maintains endothelial barrier stability.Redox Biol2020
32238653Preparation of Biodegradable PLGA-Nanoparticles Used for pH-Sensitive Intracellular Delivery of an Anti-inflammatory Bacterial Toxin to Macrophages.Chem Pharm Bull (Tokyo)2020
322010738-Nitro-cGMP modulates exocytosis in adrenal chromaffin cells.Biochem Biophys Res Commun2020
29748969Persulfide synthases that are functionally coupled with translation mediate sulfur respiration in mammalian cells.Br J Pharmacol2019
31257295Synthesis of Pegylated Manganese Protoporphyrin as a Catalase Mimic and Its Therapeutic Application to Acetaminophen-Induced Acute Liver Failure.Biol Pharm Bull2019
31282259Japanese surgical resource utilization in 2016.Int J Health Care Qual Assur2019
30853417Enhanced Cellular Polysulfides Negatively Regulate TLR4 Signaling and Mitigate Lethal Endotoxin Shock.Cell Chem Biol2019
31075303SIRT7 regulates the nuclear export of NF-κB p65 by deacetylating Ran.Biochim Biophys Acta Mol Cell Res2019
30634125Polysulfide stabilization by tyrosine and hydroxyphenyl-containing derivatives that is important for a reactive sulfur metabolomics analysis.Redox Biol2019
29168670Influence of the revision of surgical fee schedule on surgeons' productivity in Japan: A cohort analysis of 7602 surgical procedures in 2013-2016.Health Serv Manage Res2018
30107745Gold Coating of Silver Nanoplates for Enhanced Dispersion Stability and Efficient Antimicrobial Activity against Intracellular Bacteria.Langmuir2018
30026585SIRT7 has a critical role in bone formation by regulating lysine acylation of SP7/Osterix.Nat Commun2018
30197193Reactive Persulfides from Salmonella Typhimurium Downregulate Autophagy-Mediated Innate Immunity in Macrophages by Inhibiting Electrophilic Signaling.Cell Chem Biol2018
29778212Reactive Cysteine Persulphides: Occurrence, Biosynthesis, Antioxidant Activity, Methodologies, and Bacterial Persulphide Signalling.Adv Microb Physiol2018
29258821Involvement of nitric oxide/reactive oxygen species signaling via 8-nitro-cGMP formation in 1-methyl-4-phenylpyridinium ion-induced neurotoxicity in PC12 cells and rat cerebellar granule neurons.Biochem Biophys Res Commun2018
27568003Reactive sulfur species regulate tRNA methylthiolation and contribute to insulin secretion.Nucleic Acids Res2017
28169324Metabolomic profiling of reactive persulfides and polysulfides in the aqueous and vitreous humors.Sci Rep2017
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Collaborators

Institute of Development, Tohoku University
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13148Teikyo University Graduate School of Public Health
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Escola de Administracao de Empresas - FGV, Stanford University, University of California San Diego, University of Sao Paulo, Yale School of Medicine
Co-authored papers 5
Tohoku University Graduate School of Medicine, Tohoku University
Co-authored papers 4
Medical Governance Research Institute
Co-authored papers 3
The Institute of Medical Science, The University of Tokyo
Co-authored papers 2
Kumamoto University
Co-authored papers 2
University of California San Diego Health
Co-authored papers 2
Keio University School of Medicine
Co-authored papers 2
The University of Tokyo.
Co-authored papers 2
Co-authored papers 2
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Teikyo University School of Medicine, Ichihara Hospital
Co-authored papers 1
Teikyo University Chiba Medical Center
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1
Co-authored papers 1