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Author Details

Luca Fornelli
University of Oklahoma
2011
57
29
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37199141Proteomics evaluation of five economical commercial abundant protein depletion kits for enrichment of diseases-specific biomarkers from blood serum.Proteomics2023
37774690Orbitrap Mass Spectrometry and High-Field Asymmetric Waveform Ion Mobility Spectrometry (FAIMS) Enable the in-Depth Analysis of Human Serum Proteoforms.J Proteome Res2023
37252723Improved Label-Free Quantification of Intact Proteoforms Using Field Asymmetric Ion Mobility Spectrometry.Anal Chem2023
35077914Characterization of large intact protein ions by mass spectrometry: What directions should we follow?Biochim Biophys Acta Proteins Proteom2022
38069757Structural Analysis of Monoclonal Antibodies with Top-down and Middle-down Electron Transfer Dissociation Mass Spectrometry: The First Decade.Chimia (Aarau)2022
35662692Structural and Functional Characterization of a Novel Scorpion Toxin that Inhibits Na<sub>V</sub>1.8 via Interactions With the DI Voltage Sensor and DII Pore Module.Front Pharmacol2022
36269765Comprehensive characterization of the Hsp70 interactome reveals novel client proteins and interactions mediated by posttranslational modifications.PLoS Biol2022
35084980The Blood Proteoform Atlas: A reference map of proteoforms in human hematopoietic cells.Science2022
34357973Identification and Characterization of Novel Proteins from Arizona Bark Scorpion Venom That Inhibit Nav1.8, a Voltage-Gated Sodium Channel Regulator of Pain Signaling.Toxins (Basel)2021
33900069Sequential Ion-Ion Reactions for Enhanced Gas-Phase Sequencing of Large Intact Proteins in a Tribrid Orbitrap Mass Spectrometer.J Am Soc Mass Spectrom2021
33860983Mass spectrometry-based proteomic platforms for better understanding of SARS-CoV-2 induced pathogenesis and potential diagnostic approaches.Proteomics2021
34898980Evolutionary Dynamics of Indels in SARS-CoV-2 Spike Glycoprotein.Evol Bioinform Online2021
34472376Spectrum of Apolipoprotein AI and Apolipoprotein AII Proteoforms and Their Associations With Indices of Cardiometabolic Health: The CARDIA Study.J Am Heart Assoc2021
34227245Oncogenic KRAS creates an aspartate metabolism signature in colorectal cancer cells.FEBS J2021
32812765Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry.J Am Soc Mass Spectrom2020
31888965Thorough Performance Evaluation of 213 nm Ultraviolet Photodissociation for Top-down Proteomics.Mol Cell Proteomics2020
31940439Elucidating Proteoform Dynamics Underlying the Senescence Associated Secretory Phenotype.J Proteome Res2020
30571088Structural Analysis of Monoclonal Antibodies by Ultrahigh Resolution MALDI In-Source Decay FT-ICR Mass Spectrometry.Anal Chem2019
31714757Proton Transfer Charge Reduction Enables High-Throughput Top-Down Analysis of Large Proteoforms.Anal Chem2019
31607219Direct measurement of light and heavy antibody chains using ion mobility and middle-down mass spectrometry.MAbs2019
31249407Best practices and benchmarks for intact protein analysis for top-down mass spectrometry.Nat Methods2019
31248990Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding.J Biol Chem2019
30518910A comprehensive pipeline for translational top-down proteomics from a single blood draw.Nat Protoc2019
29038993The Ups and Downs of Repeated Cleavage and Internal Fragment Production in Top-Down Proteomics.J Am Soc Mass Spectrom2018
30252447Multiplexed Middle-Down Mass Spectrometry as a Method for Revealing Light and Heavy Chain Connectivity in a Monoclonal Antibody.Anal Chem2018
29894161Accurate Sequence Analysis of a Monoclonal Antibody by Top-Down and Middle-Down Orbitrap Mass Spectrometry Applying Multiple Ion Activation Techniques.Anal Chem2018
28188863Top-down proteomics: Where we are, where we are going?J Proteomics2018
29649363A Targeted, Differential Top-Down Proteomic Methodology for Comparison of ApoA-I Proteoforms in Individuals with High and Low HDL Efflux Capacity.J Proteome Res2018
29722266Chemical-Mediated Digestion: An Alternative Realm for Middle-down Proteomics?J Proteome Res2018
29610327Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk.Proc Natl Acad Sci U S A2018
29131144Top-down characterization of endogenous protein complexes with native proteomics.Nat Chem Biol2018
28076774Chromatographic efficiency and selectivity in top-down proteomics of histones.J Chromatogr B Analyt Technol Biomed Life Sci2017
28242452Top-down analysis of immunoglobulin G isotypes 1 and 2 with electron transfer dissociation on a high-field Orbitrap mass spectrometer.J Proteomics2017
28152595Advancing Top-down Analysis of the Human Proteome Using a Benchtop Quadrupole-Orbitrap Mass Spectrometer.J Proteome Res2017
28374312Defining Gas-Phase Fragmentation Propensities of Intact Proteins During Native Top-Down Mass Spectrometry.J Am Soc Mass Spectrom2017
28150248Bioinformatics Analysis of Top-Down Mass Spectrometry Data with ProSight Lite.Methods Mol Biol2017
25952688Targeted analysis of recombinant NF kappa B (RelA/p65) by denaturing and native top down mass spectrometry.J Proteomics2016
26272979Unabridged Analysis of Human Histone H3 by Differential Top-Down Mass Spectrometry Reveals Hypermethylated Proteoforms from MMSET/NSD2 Overexpression.Mol Cell Proteomics2016
27306313Progress in Top-Down Proteomics and the Analysis of Proteoforms.Annu Rev Anal Chem (Palo Alto Calif)2016
27178327Mapping Proteoforms and Protein Complexes From King Cobra Venom Using Both Denaturing and Native Top-down Proteomics.Mol Cell Proteomics2016
26780093An informatic framework for decoding protein complexes by top-down mass spectrometry.Nat Methods2016
26795204Quantitation and Identification of Thousands of Human Proteoforms below 30 kDa.J Proteome Res2016
26692813Probing Asymmetric Charge Partitioning of Protein Oligomers during Tandem Mass Spectrometry.Int J Mass Spectrom2015
26307727Ion coalescence in Fourier transform mass spectrometry: should we worry about this in shotgun proteomics?Eur J Mass Spectrom (Chichester)2015
24588056Middle-down analysis of monoclonal antibodies with electron transfer dissociation orbitrap fourier transform mass spectrometry.Anal Chem2014
25207962Advantages of extended bottom-up proteomics using Sap9 for analysis of monoclonal antibodies.Anal Chem2014
24579830Distinguishing analyte from noise components in mass spectra of complex samples: where to cut the noise?Anal Chem2014
23450212Principles of electron capture and transfer dissociation mass spectrometry applied to peptide and protein structure analysis.Chem Soc Rev2013
23967698Practical considerations for improving the productivity of mass spectrometry-based proteomics.Chimia (Aarau)2013
23934349Top-down analysis of 30-80 kDa proteins by electron transfer dissociation time-of-flight mass spectrometry.Anal Bioanal Chem2013
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Collaborators

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Co-authored papers 28
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Co-authored papers 20
and the Feinberg School of Medicine, Northwestern University
Co-authored papers 15
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Co-authored papers 15
Northwestern University
Co-authored papers 7
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Co-authored papers 7
and the Feinberg School of Medicine, Northwestern University
Co-authored papers 7
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Co-authored papers 7
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Co-authored papers 6
and the Feinberg School of Medicine, Northwestern University
Co-authored papers 6
Northwestern University
Co-authored papers 5
Florida State University
Co-authored papers 2
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Northeastern University
Co-authored papers 2
University of California los angeles
Co-authored papers 2
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Co-authored papers 2
Pacific Northwest National Laboratory
Co-authored papers 2
and the Feinberg School of Medicine, Northwestern University
Co-authored papers 2
Pacific Northwest National Laboratory
Co-authored papers 2
Feinberg School of Medicine, Northwestern University
Co-authored papers 2
University of Wisconsin-Madison College of Letters and Sciences
Co-authored papers 2
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Co-authored papers 2
and the Feinberg School of Medicine, Northwestern University
Co-authored papers 2
Purdue University
Co-authored papers 2
Florida State University
Co-authored papers 2
Institut Pasteur, Universite Paris Cite, CNRS UAR4
Co-authored papers 2
Co-authored papers 2
Institute of Chemistry, Federal University of Rio de Janeiro
Co-authored papers 1
Northwestern University Feinberg School of Medicine
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Northwestern University
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