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Author Details

Syed H E Zaidi
Ontario Institute for Cancer Research
1994
67
26
PMIDPaper TitleJournal TitlePublished Year
37090539Genotoxic colibactin mutational signature in colorectal cancer is associated with clinicopathological features, specific genomic alterations and better survival.medRxiv2024
36341526T cell-inflamed gene expression profile is associated with favorable disease-specific survival in non-hypermutated microsatellite-stable colorectal cancer patients.Cancer Med2023
36445035Body mass index and molecular subtypes of colorectal cancer.J Natl Cancer Inst2023
36648535Prognostic role of detailed colorectal location and tumor molecular features: analyses of 13,101 colorectal cancer patients including 2994 early-onset cases.J Gastroenterol2023
36707929Molecular Characteristics of Early-Onset Colorectal Cancer According to Detailed Anatomical Locations: Comparison With Later-Onset Cases.Am J Gastroenterol2023
34737207Molecular and Pathology Features of Colorectal Tumors and Patient Outcomes Are Associated with <i>Fusobacterium nucleatum</i> and Its Subspecies <i>animalis</i>.Cancer Epidemiol Biomarkers Prev2022
35668106Identifying colorectal cancer caused by biallelic MUTYH pathogenic variants using tumor mutational signatures.Nat Commun2022
35715570Association between germline variants and somatic mutations in colorectal cancer.Sci Rep2022
35247911Genetic Regulation of DNA Methylation Yields Novel Discoveries in GWAS of Colorectal Cancer.Cancer Epidemiol Biomarkers Prev2022
35089622Diagnostic yield of genome sequencing for prenatal diagnosis of fetal structural anomalies.Prenat Diagn2022
35302653Ultrastructure abnormalities of collagen and elastin in Arab patients with arterial tortuosity syndrome.J Cutan Pathol2022
33667396Response to Li and Hopper.Am J Hum Genet2021
32179488Novel and recurrent germline mutations in the VHL gene in 5 Arab patients with Von Hippel-Lindau disease.Cancer Genet2020
32088204Association Between Molecular Subtypes of Colorectal Tumors and Patient Survival, Based on Pooled Analysis of 7 International Studies.Gastroenterology2020
32686686Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival.Nat Commun2020
32758450Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk.Am J Hum Genet2020
32816852Intake of Dietary Fruit, Vegetables, and Fiber and Risk of Colorectal Cancer According to Molecular Subtypes: A Pooled Analysis of 9 Studies.Cancer Res2020
32923935Postmenopausal Hormone Therapy and Colorectal Cancer Risk by Molecularly Defined Subtypes and Tumor Location.JNCI Cancer Spectr2020
30510241Discovery of common and rare genetic risk variants for colorectal cancer.Nat Genet2019
29510987Genetic Mechanisms of Immune Evasion in Colorectal Cancer.Cancer Discov2018
29949513Hereditary 1,25-dihydroxyvitamin D-resistant rickets (HVDRR): clinical heterogeneity and long-term efficacious management of eight patients from four unrelated Arab families with a loss of function VDR mutation.J Pediatr Endocrinol Metab2018
30362320Spectrum of the KIT Gene Mutations in Gastrointestinal Stromal Tumors in Arab PatientsAsian Pac J Cancer Prev2018
30308959The Comparative Associations of Ultrasound and Computed Tomography Estimates of Muscle Quality with Physical Performance and Metabolic Parameters in Older Men.J Clin Med2018
25716334Long-range epigenetic regulation is conferred by genetic variation located at thousands of independent loci.Nat Commun2015
26404086A genome-wide association study for colorectal cancer identifies a risk locus in 14q23.1.Hum Genet2015
26368860The effect of 5-fluorouracil/leucovorin chemotherapy on CpG methylation, or the confounding role of leukocyte heterogeneity: An illustration.Genomics2015
24154973Identification of genes expressed by immune cells of the colon that are regulated by colorectal cancer-associated variants.Int J Cancer2014
24846582Enhanced proliferation and altered calcium handling in RGS2-deficient vascular smooth muscle cells.J Recept Signal Transduct Res2014
24894778Clinical, neuroimaging, and genetic features of L-2-hydroxyglutaric aciduria in Arab kindreds.Ann Saudi Med2014
21517828Clinical and molecular findings of 13 families from Saudi Arabia and a family from Sudan with homocystinuria.Clin Genet2012
21372285Peptide-mediated disruption of calmodulin-cyclin E interactions inhibits proliferation of vascular smooth muscle cells and neointima formation.Circ Res2011
19752569Novel and recurrent mutations in the C1NH gene of Arab patients affected with hereditary angioedema.Int Arch Allergy Immunol2010
20182745A novel HAX1 gene mutation in severe congenital neutropenia (SCN) associated with neurological manifestations.Eur J Pediatr2010
20117381Growth differentiation factor 5 regulates cardiac repair after myocardial infarction.J Am Coll Cardiol2010
20236109Genetics of glucose-6-phosphate dehydrogenase deficiency in Saudi patients.Clin Genet2010
20107430A common polymorphism in the cannabinoid receptor 1 (CNR1) gene is associated with antipsychotic-induced weight gain in Schizophrenia.Neuropsychopharmacology2010
18774132A novel missense and a recurrent mutation in SLC2A10 gene of patients affected with arterial tortuosity syndrome.Atherosclerosis2009
19796188A novel missense mutation in the HAX1 gene in severe congenital neutropenia patients (Kostmann disease).Clin Genet2009
19758376Novel and recurrent mutations in the AIRE gene of autoimmune polyendocrinopathy syndrome type 1 (APS1) patients.Clin Genet2009
19479054NKX2-5 regulates the expression of beta-catenin and GATA4 in ventricular myocytes.PLoS One2009
19508422Congenital diaphragmatic abnormalities in arterial tortuosity syndrome patients who carry mutations in the SLC2A10 gene.Clin Genet2009
19149905Some rare presentations of hydatid cysts: two case reports.Cases J2009
19259699Novel FBP1 gene mutations in Arab patients with fructose-1,6-bisphosphatase deficiency.Eur J Pediatr2009
18818946A novel non-sense mutation in the SLC2A10 gene of an arterial tortuosity syndrome patient of Kurdish origin.Eur J Pediatr2009
18565096Identification of a p.Ser81Arg encoding mutation in SLC2A10 gene of arterial tortuosity syndrome patients from 10 Qatari families.Clin Genet2008
18979166Grebe-type chondrodysplasia: a novel missense mutation in a conserved cysteine of the growth differentiation factor 5.J Bone Miner Metab2008
17661825Mutations in the CHX10 gene in non-syndromic microphthalmia/anophthalmia patients from Qatar.Clin Genet2007
16583246Defective glycosylation of decorin and biglycan, altered collagen structure, and abnormal phenotype of the skin fibroblasts of an Ehlers-Danlos syndrome patient carrying the novel Arg270Cys substitution in galactosyltransferase I (beta4GalT-7).J Mol Med (Berl)2006
15679832A family exhibiting arterial tortuosity syndrome displays homozygosity for markers in the arterial tortuosity locus at chromosome 20q13.Clin Genet2005
16183805Gene transfer of prostaglandin synthase maintains patency of the newborn lamb arterial duct.Pediatr Res2005
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Collaborators

Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto
Co-authored papers 19
Co-authored papers 18
Ontario Institute for Cancer Research
Co-authored papers 14
Massachusetts General Hospital and Harvard Medical School
Co-authored papers 13
German Cancer Research Center (DKFZ)
Co-authored papers 12
Mayo Clinic
Co-authored papers 12
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Co-authored papers 9
Co-authored papers 9
The Hospital for Sick Children
Co-authored papers 9
The University of Hong Kong
Co-authored papers 9
Co-authored papers 9
Ontario Institute for Cancer Research
Co-authored papers 7
Co-authored papers 7
Massachusetts General Hospital and Harvard Medical School
Co-authored papers 6
Co-authored papers 5
Mayo Clinic
Co-authored papers 4
Center for Cancer Genetic Epidemiology, University of Cambridge
Co-authored papers 4
University of Toronto
Co-authored papers 4
Fred Hutchinson Cancer Center
Co-authored papers 4
Ontario Institute for Cancer Research
Co-authored papers 4
The Ohio State University Comprehensive Cancer Center
Co-authored papers 3
University of Southern California
Co-authored papers 3
Center for Inherited Disease Research, Johns Hopkins School of Medicine
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University of Melbourne, The University of Melbourne
Co-authored papers 2
University of Washington Medical Center
Co-authored papers 2
Baylor College of Medicine
Co-authored papers 2
Broad Institute of Harvard and MIT
Co-authored papers 2