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Author Details

Kenji Shimada
Friedrich Miescher Institute for Biomedical Research
1997
33
23
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
34226278The stabilized Pol31-Pol3 interface counteracts Pol32 ablation with differential effects on repair.Life Sci Alliance2021
33843189<i>In Vitro</i>-Evolved Peptides Bind Monomeric Actin and Mimic Actin-Binding Protein Thymosin-β4.ACS Chem Biol2021
33529595Damage-induced chromatome dynamics link Ubiquitin ligase and proteasome recruitment to histone loss and efficient DNA repair.Mol Cell2021
34379448Cytoskeleton integrity influences XRCC1 and PCNA dynamics at DNA damage.Mol Biol Cell2021
34569643A regulatory phosphorylation site on Mec1 controls chromatin occupancy of RNA polymerases during replication stress.EMBO J2021
32970994DNA Damage-Induced Nucleosome Depletion Enhances Homology Search Independently of Local Break Movement.Mol Cell2020
30954333Nuclear Actin and Actin-Binding Proteins in DNA Repair.Trends Cell Biol2019
30184497Asymmetric Processing of DNA Ends at a Double-Strand Break Leads to Unconstrained Dynamics and Ectopic Translocation.Cell Rep2018
29033322Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage.Mol Cell2017
28235945A game of musical chairs: Pro- and anti-resection factors compete for TOPBP1 binding after DNA damage.J Cell Biol2017
26798134Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress.Genes Dev2016
27889450RPA Mediates Recruitment of MRX to Forks and Double-Strand Breaks to Hold Sister Chromatids Together.Mol Cell2016
25533186Yeast PP4 interacts with ATR homolog Ddc2-Mec1 and regulates checkpoint signaling.Mol Cell2015
24906321Analyzing DNA replication checkpoint in budding yeast.Methods Mol Biol2014
24035500TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks.Mol Cell2013
24705211Replication checkpoint: tuning and coordination of replication forks in s phase.Genes (Basel)2013
22625857DNA replication: Pif1 pulls the plug on stalled replication forks.Curr Biol2012
22820947An N-terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks.EMBO J2012
22504884Heterochromatin protein 1 forms distinct complexes to direct histone deacetylation and DNA methylation.Nat Struct Mol Biol2012
21194950Nuclear geometry and rapid mitosis ensure asymmetric episome segregation in yeast.Curr Biol2011
20046099Cell cycle-dependent phosphorylation of Rad53 kinase by Cdc5 and Cdc28 modulates checkpoint adaptation.Cell Cycle2010
20419146Actin-related protein Arp6 influences H2A.Z-dependent and -independent gene expression and links ribosomal protein genes to nuclear pores.PLoS Genet2010
20303249Actin-related proteins in the nucleus: life beyond chromatin remodelers.Curr Opin Cell Biol2010
19387493Lte1, Cdc14 and MEN-controlled Cdk inactivation in yeast coordinate rDNA decompaction with late telophase progression.EMBO J2009
18406137Ino80 chromatin remodeling complex promotes recovery of stalled replication forks.Curr Biol2008
17218257The origin recognition complex functions in sister-chromatid cohesion in Saccharomyces cerevisiae.Cell2007
15172673Redundancy, insult-specific sensors and thresholds: unlocking the S-phase checkpoint response.Curr Opin Genet Dev2004
12912929DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1.EMBO J2003
14512770Multiple roles of replication forks in S phase checkpoints: sensors, effectors and targets.Cell Cycle2003
12502744ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase.Genes Dev2002
12441400An N-terminal domain of Dbf4p mediates interaction with both origin recognition complex (ORC) and Rad53p and can deregulate late origin firing.Proc Natl Acad Sci U S A2002
11739961Chromosome dynamics in the yeast interphase nucleus.Science2001
9365273A nuclear matrix-associated high molecular mass nuclear antigen, HMNA, of chicken and marked decrease of its immunoreactivity during the progression of S phase.J Cell Sci1997
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Collaborators

Susan M Gasser
L'Institut Suisse de Recherche Experimentale sur le Cancer (ISREC) Foundation
Co-authored papers 29
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Center for Advanced Imaging, Harvard University
Co-authored papers 8
Nicole Hustedt
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
Co-authored papers 6
Ragna Sack
Friedrich Miescher Institute for Biomedical Research
Co-authored papers 5
Monika Tsai-Pflugfelder
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Co-authored papers 3
Fred van Leeuwen
Netherlands Cancer Institute, University of Amsterdam
Co-authored papers 2
Aude Gu??nol??
CNRS, Universite de Toulouse
Co-authored papers 2
Haico van Attikum
Leiden University Medical Center
Co-authored papers 2
Ishan Deshpande
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 2
Shigeki Nagai
Stanford University School of Medicine
Co-authored papers 1
Elisa Varela
Hospital Clinico Veterinario, Universidad de Extremadura, Avda. Universidad s/n
Co-authored papers 1
Rohith Srivas
Amgen Inc.
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Hanneke Vlaming
Blavatnik Institute, Harvard Medical School
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Trey Ideker (CM4AI)
University of California San Diego
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Bhupinder Bhullar
Novartis Institute for Biomedical Research
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Release 1.2