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Author Details

Pavlo Lutsik
Catholic University (KU) Leuven
2010
44
16
PMIDPaper TitleJournal TitlePublished Year
36368558Dynamic DNA methylation reveals novel cis-regulatory elements in mouse hematopoiesis.Exp Hematol2023
37591941Clinical impact of the genomic landscape and leukemogenic trajectories in non-intensively treated elderly acute myeloid leukemia patients.Leukemia2023
37789148Correction: Clinical impact of the genomic landscape and leukemogenic trajectories in non-intensively treated elderly acute myeloid leukemia patients.Leukemia2023
37492373Heterogeneity in the gene regulatory landscape of leiomyosarcoma.NAR Cancer2023
37024754The GAPDH redox switch safeguards reductive capacity and enables survival of stressed tumour cells.Nat Metab2023
36949154Translocation t(6;7) in AML-M4 cell line GDM-1 results in MNX1 activation through enhancer-hijacking.Leukemia2023
36632736TAL1 activation in T-cell acute lymphoblastic leukemia: a novel oncogenic 3' neo-enhancer.Haematologica2023
32822861Epigenomic technologies for precision oncology.Semin Cancer Biol2022
35737508Genetic and methylation profiles distinguish benign, malignant and spitzoid melanocytic tumors.Int J Cancer2022
35440565A leukemia-protective germline variant mediates chromatin module formation via transcription factor nucleation.Nat Commun2022
35794707Systematic evaluation of cell-type deconvolution pipelines for sequencing-based bulk DNA methylomes.Brief Bioinform2022
35931677Club cells employ regeneration mechanisms during lung tumorigenesis.Nat Commun2022
36287637Global DNA Methylation Analysis of Cancer-Associated Fibroblasts Reveals Extensive Epigenetic Rewiring Linked with RUNX1 Upregulation in Breast Cancer Stroma.Cancer Res2022
36077603Genetic and Methylation Analysis of CTNNB1 in Benign and Malignant Melanocytic Lesions.Cancers (Basel)2022
34509979Histone H3K27 demethylase KDM6A is an epigenetic gatekeeper of mTORC1 signalling in cancer.Gut2022
33100132AmpliconDesign - an interactive web server for the design of high-throughput targeted DNA methylation assays.Epigenetics2021
33526904Bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction.Commun Biol2021
33630765Versatile workflow for cell type-resolved transcriptional and epigenetic profiles from cryopreserved human lung.JCI Insight2021
34764283Epigenetic reprogramming of airway macrophages promotes polarization and inflammation in muco-obstructive lung disease.Nat Commun2021
34718742ID3 promotes homologous recombination via non-transcriptional and transcriptional mechanisms and its loss confers sensitivity to PARP inhibition.Nucleic Acids Res2021
34070078Epigenetic Modulation of Radiation-Induced Diacylglycerol Kinase Alpha Expression Prevents Pro-Fibrotic Fibroblast Response.Cancers (Basel)2021
34039737Epigenetic analysis of patients with T-ALL identifies poor outcomes and a hypomethylating agent-responsive subgroup.Sci Transl Med2021
33346800Methrix: an R/Bioconductor package for systematic aggregation and analysis of bisulfite sequencing data.Bioinformatics2021
32188505Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL.Genome Med2020
32005851Neuronal ensemble-specific DNA methylation strengthens engram stability.Nat Commun2020
33110075Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone.Nat Commun2020
32978601Reference-free deconvolution, visualization and interpretation of complex DNA methylation data using DecompPipeline, MeDeCom and FactorViz.Nat Protoc2020
30615206Integrative Analysis Defines Distinct Prognostic Subgroups of Intrahepatic Cholangiocarcinoma.Hepatology2019
31064978DNA methylation signatures of monozygotic twins clinically discordant for multiple sclerosis.Nat Commun2019
30871603RnBeads 2.0: comprehensive analysis of DNA methylation data.Genome Biol2019
30664630Enhancer hijacking activates oncogenic transcription factor NR4A3 in acinic cell carcinomas of the salivary glands.Nat Commun2019
30537508From Basic Knowledge to Effective Therapies.Cancer Cell2018
30045751DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.Epigenetics Chromatin2018
30537516Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories.Cancer Cell2018
28340624MeDeCom: discovery and quantification of latent components of heterogeneous methylomes.Genome Biol2017
27119776Mitochondrial DNA Variation and Heteroplasmy in Monozygotic Twins Clinically Discordant for Multiple Sclerosis.Hum Mutat2016
26185018Epigenome data release: a participant-centered approach to privacy protection.Genome Biol2015
24875479BiQ Analyzer HiMod: an interactive software tool for high-throughput locus-specific analysis of 5-methylcytosine and its oxidized derivatives.Nucleic Acids Res2014
25553811AKSmooth: enhancing low-coverage bisulfite sequencing data via kernel-based smoothing.J Bioinform Comput Biol2014
25262207Comprehensive analysis of DNA methylation data with RnBeads.Nat Methods2014
23706164Adult monozygotic twins discordant for intra-uterine growth have indistinguishable genome-wide DNA methylation profiles.Genome Biol2013
23803588Bi-PROF: bisulfite profiling of target regions using 454 GS FLX Titanium technology.Epigenetics2013
21565797BiQ Analyzer HT: locus-specific analysis of DNA methylation by high-throughput bisulfite sequencing.Nucleic Acids Res2011
19948534Assisted reproductive technologies do not enhance the variability of DNA methylation imprints in human.J Med Genet2010
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Collaborators

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German Cancer Research Center
Co-authored papers 28
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German Cancer Research Center (DKFZ)
Co-authored papers 15
Jörn Walter
Co-authored papers 14
Reka Toth
German Cancer Research Center (DKFZ)
Co-authored papers 12
Yassen Assenov
German Cancer Research Center (DKFZ)
Co-authored papers 6
Matthias Schlesner
University of Augsburg
Co-authored papers 4
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CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 4
Gilles Gasparoni
Co-authored papers 4
Sebastian M Waszak
University of California san francisco
Co-authored papers 3
Lars Feuerbach
German Cancer Research Center (DKFZ)
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Antje Sucker
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Berlin Institute of Health (BIH) and Charite
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Dirk Schadendorf
Co-authored papers 2
Julia Arand
Medical University of Vienna
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European Bioinformatics Institute (EMBL-EBI)
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German Cancer Research Center (DKFZ)
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Institute of Pathology, University Hospital Heidelberg
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Vyacheslav Amstislavskiy
Max-Planck-Institute for Molecular Genetics
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Jens Langstein
German Cancer Research Center (DKFZ) & National Center for Tumor Diseases (NCT)
Co-authored papers 1
S??ren Matzk
Max Planck Institute for Molecular Genetics
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Frank Westermann
Co-authored papers 1
Ronald Simon
Institute of Pathology, University Medical Center Hamburg-Eppendorf
Co-authored papers 1
Thomas Albrecht
Institute of Pathology, Heidelberg University Hospital
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Guido Sauter
Institute of Pathology, University Medical Center Hamburg-Eppendorf
Co-authored papers 1
Marie-Laure Yaspo
Max Planck Institute for Molecular Genetics
Co-authored papers 1
Francesco Favero
Universita del Piemonte Orientale
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Markus Ralser
Charite - Universitatsmedizin Berlin
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