Author details

Full Name

Jesse M Engreitz

Affiliation

ORCID

Career Start Year

2010

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37443254	Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases.	Nat Genet	2023
38014075	An encyclopedia of enhancer-gene regulatory interactions in the human genome.	bioRxiv	2023
37989727	Reduced FOXF1 links unrepaired DNA damage to pulmonary arterial hypertension.		2023
37205448	Selective Enhancer Dependencies in -Intact and -Rearranged Germinal Center B-cell Diffuse Large B-cell Lymphoma.		2023
35132965	Computational estimates of annular diameter reveal genetic determinants of mitral valve function and disease.	JCI Insight	2022
35594906	Compatibility rules of human enhancer and promoter sequences.	Nature	2022
36175791	Identifying disease-critical cell types and cellular processes by integrating single-cell RNA-sequencing and human genetics.	Nat Genet	2022
35999210	KLF4 recruits SWI/SNF to increase chromatin accessibility and reprogram the endothelial enhancer landscape under laminar shear stress.	Nat Commun	2022
35873673	SNP-to-gene linking strategies reveal contributions of enhancer-related and candidate master-regulator genes to autoimmune disease.	Cell Genomics	2022
35668300	Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity.	Nat Genet	2022
36563664	Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease.	Cell	2022
34970970	Systematic identification of genomic elements that regulate FCGR2A expression and harbor variants linked with autoimmune disease.	Hum Mol Genet	2022
34845454	Identifying disease-critical cell types and cellular processes across the human body by integration of single-cell profiles and human genetics.	bioRxiv	2021
33542524	Activity-dependent regulome of human GABAergic neurons reveals new patterns of gene regulation and neurological disease heritability.	Nature Neuroscience	2021
33828297	Genome-wide enhancer maps link risk variants to disease genes.	Nature	2021
33655247	A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2.	bioRxiv	2021
33915569	COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets.	Nature	2021
33376219	HyPR-seq: Single-cell quantification of chosen RNAs via hybridization and sequencing of DNA probes.	Proc Natl Acad Sci U S A	2020
32144282	Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features.	Nat Commun	2020
31371352	CRISPR Tools for Systematic Studies of RNA Regulation.	Cold Spring Harb Perspect Biol	2019
31784727	Activity-by-contact model of enhancer-promoter regulation from thousands of CRISPR perturbations.	Nat Genet	2019
31492842	Functional disease architectures reveal unique biological role of transposable elements.	Nat Commun	2019
31070582	Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis.	Elife	2019
29551269	Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis.	Cell	2018
30504875	CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data.	Nat Methods	2018
29973585	Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries.	Nat Commun	2018
30150775	The NORAD lncRNA assembles a topoisomerase complex critical for genome stability.	Nature	2018
30140049	Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries.	Nat Commun	2018
30140000	Deep-coverage whole genome sequences and blood lipids among 16,324 individuals.	Nat Commun	2018
30279576	Publisher Correction: The NORAD lncRNA assembles a topoisomerase complex critical for genome stability.	Nature	2018
29987030	Positional specificity of different transcription factor classes within enhancers.	Proc Natl Acad Sci U S A	2018
28137873	Systematic dissection of genomic features determining transcription factor binding and enhancer function.	Proc Natl Acad Sci U S A	2017
28985562	Cohesin Loss Eliminates All Loop Domains.	Cell	2017
28753427	A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression.	Cell	2017
28933431	Erratum: Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood.	Nature	2017
28792927	Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood.	Nature	2017
28658208	Recurrent and functional regulatory mutations in breast cancer.	Nature	2017
27775706	Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses.	Nat Med	2016
27708057	Systematic mapping of functional enhancer-promoter connections with CRISPR interference.	Science	2016
27783602	Local regulation of gene expression by lncRNA promoters, transcription and splicing.	Nature	2016
27780979	Long non-coding RNAs: spatial amplifiers that control nuclear structure and gene expression.	Nat Rev Mol Cell Biol	2016
25555582	RNA antisense purification (RAP) for mapping RNA interactions with chromatin.	Methods Mol Biol	2015
25219674	Transcriptome-wide mapping reveals widespread dynamic-regulated pseudouridylation of ncRNA and mRNA.	Cell	2014
25259926	RNA-RNA interactions enable specific targeting of noncoding RNAs to nascent Pre-mRNAs and chromatin sites.	Cell	2014
24177178	Neuregulin autocrine signaling promotes self-renewal of breast tumor-initiating cells by triggering HER2/HER3 activation.	Cancer Research	2014
24463464	Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre.	Nat Struct Mol Biol	2014
23828888	The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome.	Science	2013
23028501	Three-dimensional genome architecture influences partner selection for chromosomal translocations in human disease.	PLoS ONE	2012
21962509	The Lin28/let-7 axis regulates glucose metabolism.	Cell	2011
21967760	ProfileChaser: searching microarray repositories based on genome-wide patterns of differential expression.	Bioinformatics	2011