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Author Details

Christopher A Bristow
The University of Texas MD Anderson Cancer Center
2005
56
32
PMIDPaper TitleJournal TitlePublished Year
36350677PICKLES v3: the updated database of pooled in vitro CRISPR knockout library essentiality screens.Nucleic Acids Res2023
36350677PICKLES v3: the updated database of pooled in vitro CRISPR knockout library essentiality screens.Nucleic Acids Res2023
36440915Easy NanoString nCounter data analysis with the NanoTube.Bioinformatics2023
36747713Combined KRAS<sup>G12C</sup> and SOS1 inhibition enhances and extends the anti-tumor response in KRAS<sup>G12C</sup>-driven cancers by addressing intrinsic and acquired resistance.bioRxiv2023
36658425Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials.Nat Med2023
36747713Combined KRAS<sup>G12C</sup> and SOS1 inhibition enhances and extends the anti-tumor response in KRAS<sup>G12C</sup>-driven cancers by addressing intrinsic and acquired resistance.bioRxiv2023
36440915Easy NanoString nCounter data analysis with the NanoTube.Bioinformatics2023
36658425Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials.Nat Med2023
35138907A functional genomic approach to actionable gene fusions for precision oncology.Sci Adv2022
35944232Shared Nearest Neighbors Approach and Interactive Browser for Network Analysis of a Comprehensive Non-Small-Cell Lung Cancer Data Set.JCO Clin Cancer Inform2022
35138907A functional genomic approach to actionable gene fusions for precision oncology.Sci Adv2022
35944232Shared Nearest Neighbors Approach and Interactive Browser for Network Analysis of a Comprehensive Non-Small-Cell Lung Cancer Data Set.JCO Clin Cancer Inform2022
33158812Loss of ARID1A Promotes Epithelial-Mesenchymal Transition and Sensitizes Pancreatic Tumors to Proteotoxic Stress.Cancer Res2021
33745946Sequential Administration of XPO1 and ATR Inhibitors Enhances Therapeutic Response in TP53-mutated Colorectal Cancer.Gastroenterology2021
34117030Targeting Glucose Metabolism Sensitizes Pancreatic Cancer to MEK Inhibition.Cancer Res2021
34108622Combined inhibition of DDR1 and CDK4/6 induces synergistic effects in ER-positive, HER2-negative breast cancer with PIK3CA/AKT1 mutations.Oncogene2021
33839689Oncogenic <i>KRAS</i> Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis.Cancer Discov2021
34330913PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma.Nat Commun2021
34309585Targeting CDK4 overcomes EMT-mediated tumor heterogeneity and therapeutic resistance in KRAS-mutant lung cancer.JCI Insight2021
33158812Loss of ARID1A Promotes Epithelial-Mesenchymal Transition and Sensitizes Pancreatic Tumors to Proteotoxic Stress.Cancer Res2021
34518211Oxidative Phosphorylation Is a Metabolic Vulnerability in Chemotherapy-Resistant Triple-Negative Breast Cancer.Cancer Res2021
34777916Short-term treatment with multi-drug regimens combining BRAF/MEK-targeted therapy and immunotherapy results in durable responses in <i>Braf</i>-mutated melanoma.Oncoimmunology2021
34359705Synthetic Lethality Screening Highlights Colorectal Cancer Vulnerability to Concomitant Blockade of NEDD8 and EGFR Pathways.Cancers (Basel)2021
33839689Oncogenic <i>KRAS</i> Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis.Cancer Discov2021
33745946Sequential Administration of XPO1 and ATR Inhibitors Enhances Therapeutic Response in TP53-mutated Colorectal Cancer.Gastroenterology2021
34518211Oxidative Phosphorylation Is a Metabolic Vulnerability in Chemotherapy-Resistant Triple-Negative Breast Cancer.Cancer Res2021
34777916Short-term treatment with multi-drug regimens combining BRAF/MEK-targeted therapy and immunotherapy results in durable responses in <i>Braf</i>-mutated melanoma.Oncoimmunology2021
34117030Targeting Glucose Metabolism Sensitizes Pancreatic Cancer to MEK Inhibition.Cancer Res2021
34359705Synthetic Lethality Screening Highlights Colorectal Cancer Vulnerability to Concomitant Blockade of NEDD8 and EGFR Pathways.Cancers (Basel)2021
34309585Targeting CDK4 overcomes EMT-mediated tumor heterogeneity and therapeutic resistance in KRAS-mutant lung cancer.JCI Insight2021
34330913PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma.Nat Commun2021
34108622Combined inhibition of DDR1 and CDK4/6 induces synergistic effects in ER-positive, HER2-negative breast cancer with PIK3CA/AKT1 mutations.Oncogene2021
32928921Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib.Cancer Res2020
32928921Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib.Cancer Res2020
33087697Vestigial-like 1 is a shared targetable cancer-placenta antigen expressed by pancreatic and basal-like breast cancers.Nat Commun2020
33118821Discovery of IPN60090, a Clinical Stage Selective Glutaminase-1 (GLS-1) Inhibitor with Excellent Pharmacokinetic and Physicochemical Properties.J Med Chem2020
33118821Discovery of IPN60090, a Clinical Stage Selective Glutaminase-1 (GLS-1) Inhibitor with Excellent Pharmacokinetic and Physicochemical Properties.J Med Chem2020
33087697Vestigial-like 1 is a shared targetable cancer-placenta antigen expressed by pancreatic and basal-like breast cancers.Nat Commun2020
30625329Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation.Cell Rep2019
31719531ZEB1/NuRD complex suppresses TBC1D2b to stimulate E-cadherin internalization and promote metastasis in lung cancer.Nat Commun2019
31815044BRCA1 identified as a modulator of temozolomide resistance in P53 wild-type GBM using a high-throughput shRNA-based synthetic lethality screening.Am J Cancer Res2019
31610796Global impact of somatic structural variation on the DNA methylome of human cancers.Genome Biol2019
31557131YAP1 oncogene is a context-specific driver for pancreatic ductal adenocarcinoma.JCI Insight2019
30625329Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation.Cell Rep2019
30986992Ntrk1 Promotes Resistance to PD-1 Checkpoint Blockade in Mesenchymal Kras/p53 Mutant Lung Cancer.Cancers (Basel)2019
31492820Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS-Dependent Pancreatic Ductal Adenocarcinoma.Cancer Res2019
30867319ZEB1 suppression sensitizes KRAS mutant cancers to MEK inhibition by an IL17RD-dependent mechanism.Sci Transl Med2019
30996079Resistance to neoadjuvant chemotherapy in triple-negative breast cancer mediated by a reversible drug-tolerant state.Sci Transl Med2019
31815044BRCA1 identified as a modulator of temozolomide resistance in P53 wild-type GBM using a high-throughput shRNA-based synthetic lethality screening.Am J Cancer Res2019
31719531ZEB1/NuRD complex suppresses TBC1D2b to stimulate E-cadherin internalization and promote metastasis in lung cancer.Nat Commun2019
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Collaborators

Timothy P Heffernan
Co-authored papers 27
Sahil Seth
The University of Texas MD Anderson Cancer Center
Co-authored papers 13
Jianhua Zhang
University of Texas MD Anderson Cancer Center
Co-authored papers 9
Raju Kucherlapati
Harvard Medical School
Co-authored papers 8
Lixing Yang
University of Chicago, USA University of Chicago Comprehensive Cancer Center
Co-authored papers 8
Peter J Park
Harvard Medical School
Co-authored papers 8
Angeliki Pantazi
Harvard Medical School, Brigham and Women's Hospital
Co-authored papers 7
Anirban Maitra
The University of Texas MD Anderson Cancer Center
Co-authored papers 7
Xiaojia Ren
University of Kentucky College of Medicine
Co-authored papers 7
Alexei Protopopov
The University of MD Anderson Cancer Center
Co-authored papers 7
Jeffrey J Kovacs
Co-authored papers 6
Chad J Creighton
Co-authored papers 6
Angela Hadjipanayis
Harvard Medical School, Brigham and Women's Hospital
Co-authored papers 6
Semin Lee
Ulsan National Institute of Science and Technology (UNIST)
Co-authored papers 6
Jonathan G Seidman
Harvard Medical School
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Jiabin Tang
The University of MD Anderson Cancer Center
Co-authored papers 6
Xingzhi Song
The University of Texas MD Anderson Cancer Center
Co-authored papers 6
Harshad S Mahadeshwar
The University of MD Anderson Cancer Center
Co-authored papers 6
Gordon B Mills
Knight Cancer Institute, Oregon Health and Sciences University
Co-authored papers 5
Lynda Chin
Co-authored papers 5
Andrea Viale
The University of Texas MD Anderson Cancer Center
Co-authored papers 5
Funda Meric-Bernstam
University of Texas MD Anderson Cancer Center
Co-authored papers 5
Scott Kopetz
University of Texas MD Anderson Cancer Center
Co-authored papers 5
Lynda Chin
The University of MD Anderson Cancer Center
Co-authored papers 5
Amy G Robertson
Present address: Dxige Research Inc.
Co-authored papers 4
Huandong Sun
Co-authored papers 4
Han Liang
MD Anderson Cancer Center
Co-authored papers 4
Roel G W Verhaak
Yale School of Medicine
Co-authored papers 4
Manolis Kellis
Massachusetts Institute of Technology
Co-authored papers 4
Alexander J Lazar
The University of Texas MD Anderson Cancer Center
Co-authored papers 4
Release 1.2