Author details

Full Name

David M Lee

Affiliation

ORCID

Career Start Year

1994

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
32381123	Circulating TNF-like protein 1A (TL1A) is elevated early in rheumatoid arthritis and depends on TNF.	Arthritis Res Ther	2020
27502297	Î²-Defensin 2 is a responsive biomarker of IL-17A-driven skin pathology in patients with psoriasis.	Journal of Allergy and Clinical Immunology	2017
26268815	Association of HLA-DRB1 alleles with clinical responses to the anti-interleukin-17A monoclonal antibody secukinumab in active rheumatoid arthritis.	Rheumatology	2016
25975695	Evidence for cadherin-11 cleavage in the synovium and partial characterization of its mechanism.		2015
25828362	Evidence that a neutrophil-keratinocyte crosstalk is an early target of IL-17A inhibition in psoriasis.	Experimental Dermatology	2015
25642942	Anti-lubricin monoclonal antibodies created using lubricin-knockout mice immunodetect lubricin in several species and in patients with healthy and diseased joints.	PLoS ONE	2015
23165896	The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes.	EMBO Molecular Medicine	2013
23935208	G protein-coupled receptor kinase-3-deficient mice exhibit WHIM syndrome features and attenuated inflammatory responses.	Journal of Leukocyte Biology	2013
24174326	Immune-mediated pore-forming pathways induce cellular hypercitrullination and generate citrullinated autoantigens in rheumatoid arthritis.	Sci Transl Med	2013
23400684	Proteomic analysis of synovial fluid from the osteoarthritic knee: comparison with transcriptome analyses of joint tissues.	Arthritis Rheum	2013
23253932	Effect of IL-17A blockade with secukinumab in autoimmune diseases.	Annals of the Rheumatic Diseases	2013
23063331	Leukotriene B4-driven neutrophil recruitment to the skin is essential for allergic skin inflammation.	Immunity	2012
22390545	Hypogalactosylation of serum N-glycans fails to predict clinical response to methotrexate and TNF inhibition in rheumatoid arthritis.		2012
22057346	Identification of a central role for complement in osteoarthritis.	Nat Med	2011
21305505	Erroneous augmentation of multiplex assay measurements in patients with rheumatoid arthritis due to heterophilic binding by serum rheumatoid factor.	Arthritis Rheum	2011
21173247	Essential role for mast cell tryptase in acute experimental colitis.	Proc Natl Acad Sci U S A	2011
21123167	A role for serglycin proteoglycan in mast cell apoptosis induced by a secretory granule-mediated pathway.	Journal of Biological Chemistry	2011
21404422	On-demand drug delivery from self-assembled nanofibrous gels: a new approach for treatment of proteolytic disease.	J Biomed Mater Res A	2011
21280001	Regulation of human neutrophil FcÎ³ receptor IIa by C5a receptor promotes inflammatory arthritis in mice.		2011
21279996	Synovial inflammation in patients undergoing arthroscopic meniscectomy: molecular characterization and relationship to symptoms.	Arthritis Rheum	2011
21536877	Cadherin-11 regulates fibroblast inflammation.	Proceedings of the National Academy of Sciences of the United States of America	2011
21357261	Platelets participate in synovitis via Cox-1-dependent synthesis of prostacyclin independently of microparticle generation.	Journal of Immunology	2011
21930706	Chemerin158K protein is the dominant chemerin isoform in synovial and cerebrospinal fluids but not in plasma.	Journal of Biological Chemistry	2011
21926349	PTEN deficiency in mast cells causes a mastocytosis-like proliferative disease that heightens allergic responses and vascular permeability.	Blood	2011
21804193	Plasma carboxypeptidase B downregulates inflammatory responses in autoimmune arthritis.	J Clin Invest	2011
20656922	Nonredundant roles for leukotriene B4 receptors BLT1 and BLT2 in inflammatory arthritis.	Journal of Immunology	2010
20844192	Development of a nascent galectin-1 chimeric molecule for studying the role of leukocyte galectin-1 ligands and immune disease modulation.	Journal of Immunology	2010
20876351	Joint tissues amplify inflammation and alter their invasive behavior via leukotriene B4 in experimental inflammatory arthritis.	Journal of Immunology	2010
20832582	Mast cell protease 6 is required for allograft tolerance.		2010
20533289	A functional RANKL polymorphism associated with younger age at onset of rheumatoid arthritis.	Arthritis Rheum	2010
20181277	c-Fms-mediated differentiation and priming of monocyte lineage cells play a central role in autoimmune arthritis.		2010
20131230	Synovial fibroblasts self-direct multicellular lining architecture and synthetic function in three-dimensional organ culture.	Arthritis Rheum	2010
20432503	A novel anti-inflammatory role for secretory phospholipase A2 in immune complex-mediated arthritis.	EMBO Mol Med	2010
20038636	Loss of CD34 leads to exacerbated autoimmune arthritis through increased vascular permeability.	Journal of Immunology	2010
20427273	Synovial fibroblasts promote the expression and granule accumulation of tryptase via interleukin-33 and its receptor ST-2 (IL1RL1).	J Biol Chem	2010
20110505	Platelets amplify inflammation in arthritis via collagen-dependent microparticle production.	Science	2010
20506563	Aberrant IgG galactosylation precedes disease onset, correlates with disease activity, and is prevalent in autoantibodies in rheumatoid arthritis.	Arthritis Rheum	2010
20191628	Neutrophils in a mouse model of autoantibody-mediated arthritis: critical producers of Fc receptor gamma, the receptor for C5a, and lymphocyte function-associated antigen 1.		2010
20662064	C5a receptor enables participation of mast cells in immune complex arthritis independently of FcÎ³ receptor modulation.		2010
18390910	Quantifying anti-cyclic citrullinated peptide titres: clinical utility and association with tobacco exposure in patients with rheumatoid arthritis.	Annals of the Rheumatic Diseases	2009
19404963	Cadherin 11 promotes invasive behavior of fibroblast-like synoviocytes.		2009
19109198	Mast cells contribute to autoimmune inflammatory arthritis via their tryptase/heparin complexes.	J Immunol	2009
19561612	Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair.	Nature Immunology	2009
19790060	Thrombin-activatable carboxypeptidase B cleavage of osteopontin regulates neutrophil survival and synoviocyte binding in rheumatoid arthritis.		2009
19922019	S100A9 is not essential for disease expression in an acute (K/BxN) or chronic (CIA) model of inflammatory arthritis.	Scandinavian Journal of Rheumatology	2009
18354212	Mouse mast cell tryptase mMCP-6 is a critical link between adaptive and innate immunity in the chronic phase of Trichinella spiralis infection.	J Immunol	2008
19075240	The nuclear membrane organization of leukotriene synthesis.	Proc Natl Acad Sci U S A	2008
18988802	Genetic inversion in mast cell-deficient (Wsh) mice interrupts corin and manifests as hematopoietic and cardiac aberrancy.	Am J Pathol	2008
18438856	Predominance of cyclooxygenase 1 over cyclooxygenase 2 in the generation of proinflammatory prostaglandins in autoantibody-driven K/BxN serum-transfer arthritis.	Arthritis Rheum	2008
18391064	Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice.	J Exp Med	2008