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Author Details

Luc Dirix
GZA Ziekenhuizen Campus Sint-Augustinus, University of Antwerp
1988
359
82
PMIDPaper TitleJournal TitlePublished Year
37939105Paclitaxel plus Eftilagimod Alpha, a Soluble LAG-3 Protein, in Metastatic, HR+ Breast Cancer: Results from AIPAC, a Randomized, Placebo Controlled Phase IIb Trial.Clin Cancer Res2024
36031469Tumor biology reflected by histological growth pattern is more important than surgical margin for the prognosis of patients undergoing resection of colorectal liver metastases.Eur J Surg Oncol2023
37965465Histopathological growth pattern of liver metastases as an independent marker of metastatic behavior in different primary cancers.Front Oncol2023
37596278An idiosyncratic zonated stroma encapsulates desmoplastic liver metastases and originates from injured liver.Nat Commun2023
37573673Association of body mass index with clinicopathological features and survival in patients with primary invasive lobular breast cancer.Eur J Cancer2023
37236636First-in-human phase Ib trial of M9241 (NHS-IL12) plus avelumab in patients with advanced solid tumors, including dose expansion in patients with advanced urothelial carcinoma.J Immunother Cancer2023
36717676Comment on 'Use the term "infiltrative" instead of "replacement" when defining histopathological growth pattern in patients with liver cancer' by Kong B et al.Br J Cancer2023
36717329Comparison of the genomic alterations present in tumor samples from patients with metastatic inflammatory versus non-inflammatory breast cancer reveals AURKA as a potential treatment target.Breast2023
36368320Challenges in neoantigen-directed therapeutics.Cancer Cell2023
34844889The Place of Chemotherapy in The Evolving Treatment Landscape for Patients With HR-positive/HER2-negative MBC.Clin Breast Cancer2022
35650276Histopathological growth patterns of liver metastasis: updated consensus guidelines for pattern scoring, perspectives and recent mechanistic insights.Br J Cancer2022
35397078Circulating tumor cell detection: A prospective comparison between CellSearch® and RareCyte® platforms in patients with progressive metastatic breast cancer.Breast Cancer Res Treat2022
35790747Interrogating breast cancer heterogeneity using single and pooled circulating tumor cell analysis.NPJ Breast Cancer2022
35526835Discordance between Immunohistochemistry and Erb-B2 Receptor Tyrosine Kinase 2 mRNA to Determine Human Epidermal Growth Factor Receptor 2 Low Status for Breast Cancer.J Mol Diagn2022
35132503Coagulation/fibrinolysis and circulating tumor cells in patients with advanced breast cancer.Breast Cancer Res Treat2022
34921020Assessing CSF ctDNA to Improve Diagnostic Accuracy and Therapeutic Monitoring in Breast Cancer Leptomeningeal Metastasis.Clin Cancer Res2022
35042871Comparative transcriptional analyses of preclinical models and patient samples reveal MYC and RELA driven expression patterns that define the molecular landscape of IBC.NPJ Breast Cancer2022
35278078Modeling the Prognostic Impact of Circulating Tumor Cells Enumeration in Metastatic Breast Cancer for Clinical Trial Design Simulation.Oncologist2022
35063943Prospective non-interventional BELOVA/BGOG-ov16 study on safety of frontline bevacizumab in elderly patients with FIGO stage IV ovarian cancer: a study of the Belgian and Luxembourg Gynaecological Oncology Group.Int J Gynecol Cancer2022
32735852Can medical imaging identify the histopathological growth patterns of liver metastases?Semin Cancer Biol2021
33655422Type IV collagen as a potential biomarker of metastatic breast cancer.Clin Exp Metastasis2021
33852104A phase 1a/1b trial of CSF-1R inhibitor LY3022855 in combination with durvalumab or tremelimumab in patients with advanced solid tumors.Invest New Drugs2021
33808193Increased Pathway Complexity Is a Prognostic Biomarker in Metastatic Castration-Resistant Prostate Cancer.Cancers (Basel)2021
33751583Clinico-metabolic characterization improves the prognostic value of histological growth patterns in patients undergoing surgery for colorectal liver metastases.J Surg Oncol2021
34133923Tumor vessel co-option probed by single-cell analysis.Cell Rep2021
34104544Immune landscape of inflammatory breast cancer suggests vulnerability to immune checkpoint inhibitors.Oncoimmunology2021
34238931Comparative survival analysis of multiparametric tests-when molecular tests disagree-A TEAM Pathology study.NPJ Breast Cancer2021
33307151Stereotactic Ablative Radiation Therapy to All Lesions in Patients With Oligometastatic Cancers: A Phase 1 Dose-Escalation Trial.Int J Radiat Oncol Biol Phys2021
33230201Automated enumeration and phenotypic characterization of CTCs and tdEVs in patients with metastatic castration resistant prostate cancer.Prostate Cancer Prostatic Dis2021
32770247Serial Analysis of Circulating Tumor Cells in Metastatic Breast Cancer Receiving First-Line Chemotherapy.J Natl Cancer Inst2021
32423453Quantitative hormone receptor (HR) expression and gene expression analysis in HR+ inflammatory breast cancer (IBC) vs non-IBC.BMC Cancer2020
31801732Efficacy and Tolerability of Tremelimumab in Locally Advanced or Metastatic Urothelial Carcinoma Patients Who Have Failed First-Line Platinum-Based Chemotherapy.Clin Cancer Res2020
32043194Inflammatory breast cancer cells are characterized by abrogated TGFβ1-dependent cell motility and SMAD3 activity.Breast Cancer Res Treat2020
31655928Pathological features of vessel co-option versus sprouting angiogenesis.Angiogenesis2020
31854063NOTCH and DNA repair pathways are more frequently targeted by genomic alterations in inflammatory than in non-inflammatory breast cancers.Mol Oncol2020
33339824Association between the histopathological growth patterns of liver metastases and survival after hepatic surgery in breast cancer patients.NPJ Breast Cancer2020
33037118Avelumab as second-line therapy for metastatic, platinum-treated urothelial carcinoma in the phase Ib JAVELIN Solid Tumor study: 2-year updated efficacy and safety analysis.J Immunother Cancer2020
32890963A high neutrophil-lymphocyte ratio and platelet-lymphocyte ratio are associated with a worse outcome in inflammatory breast cancer.Breast2020
32998962Phase Ib Dose-escalation/Expansion Trial of Ribociclib in Combination With Everolimus and Exemestane in Postmenopausal Women with HR<sup>+</sup>, HER2<sup>-</sup> Advanced Breast Cancer.Clin Cancer Res2020
32679307The use of simulation-CT's as a coronavirus disease 2019 screening tool during the severe acute respiratory syndrome coronavirus 2 pandemic.Radiother Oncol2020
32356465Phase II open-label study investigating apalutamide in patients with biochemical progression after radical prostatectomy.Future Oncol2020
32205863Immune phenotype and histopathological growth pattern in patients with colorectal liver metastases.Br J Cancer2020
32269140Efficacy and safety of avelumab treatment in patients with metastatic Merkel cell carcinoma: experience from a global expanded access program.J Immunother Cancer2020
30637550Angiogenic desmoplastic histopathological growth pattern as a prognostic marker of good outcome in patients with colorectal liver metastases.Angiogenesis2019
31921184Comparative Profiling of Metastatic 4T1- vs. Non-metastatic Py230-Based Mammary Tumors in an Intraductal Model for Triple-Negative Breast Cancer.Front Immunol2019
30209161<i>TP53</i> Outperforms Other Androgen Receptor Biomarkers to Predict Abiraterone or Enzalutamide Outcome in Metastatic Castration-Resistant Prostate Cancer.Clin Cancer Res2019
31180178AR splice variants in circulating tumor cells of patients with castration-resistant prostate cancer: relation with outcome to cabazitaxel.Mol Oncol2019
31265358Predictive Significance of Androgen Receptor Splice Variant 7 in Patients With Metastatic Castration-Resistant Prostate Cancer: The PROPHECY Study.J Clin Oncol2019
31483799HER-2 status of circulating tumor cells in a metastatic breast cancer cohort: A comparative study on characterization techniques.PLoS One2019
31255421Re: Fabian Lohaus, Klaus Zöphel, Steffen Löck, et al. Can Local Ablative Radiotherapy Revert Castration-resistant Prostate Cancer to an Earlier Stage of Disease? Eur Urol 2019;75:548-51.Eur Urol2019
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Collaborators

Erasmus Medical Center
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Leiden University Medical Center: Leids Universitair Medisch Centrum.
Co-authored papers 18
National and Kapodistrian University of Athens
Co-authored papers 14
Institute of Cancer and Genomic Sciences, The University of Birmingham
Co-authored papers 14
University Medical Center, Johannes Gutenberg University Mainz
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Cancer Research Center of Hawaii: University of Hawai'i Cancer Center.
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Erasmus Medical Center (MC) Cancer Institute
Co-authored papers 13
Erasmus MC Cancer Institute, University Medical Center Rotterdam
Co-authored papers 13
University of Edinburgh
Co-authored papers 13
University of Oxford
Co-authored papers 12
Helios Medical Centre
Co-authored papers 9
Franciscus Gasthuis & Vlietland Hospital Rotterdam and Schiedam
Co-authored papers 9
Co-authored papers 9
Weill Cornell School of Medicine
Co-authored papers 8
University of Edinburgh
Co-authored papers 7
Co-authored papers 7
Karolinska Institute
Co-authored papers 6
Leicester Clinical Trials Unit, University of Leicester
Co-authored papers 6
Karolinska Institute
Co-authored papers 6
The University of Texas MD Anderson Cancer Center
Co-authored papers 6
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 5
Queen Elizabeth University Hospital
Co-authored papers 5
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Ghent University, GZA Ziekenhuizen
Co-authored papers 5
Erasmus MC Cancer Institute
Co-authored papers 4
University of Texas M.D. Anderson Cancer Center
Co-authored papers 4
Champalimaud Clinical Center/Champalimaud Foundation
Co-authored papers 4
Ontario Institute for Cancer Research
Co-authored papers 4
University Hospital Zurich
Co-authored papers 3
Ontario Institute for Cancer Research
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