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Author Details

Kaiyu Jiang
University at Buffalo School of Medicine and Biomedical Sciences
2003
49
15
Aidong Zhang (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37202122B lymphocytes in treatment-naive paediatric patients with lupus are epigenetically distinct from healthy children.Lupus Sci Med2023
37745336Comparison of the three-dimensional chromatin structures of adolescent and adult peripheral blood B cells: implications for the study of pediatric autoimmune diseases.bioRxiv2023
34474283Glycine and serine markedly eliminate methylglyoxal in the presence of formaldehyde via the formation of imidazole salts.Food Chem2022
35804791Origin and Fate of Acrolein in Foods.Foods2022
35669074Formation and Identification of Six Amino Acid - Acrylamide Adducts and Their Cytotoxicity Toward Gastrointestinal Cell Lines.Front Nutr2022
36248892Analysis of chromatin data supports a role for CD14+ monocytes/macrophages in mediating genetic risk for juvenile idiopathic arthritis.Front Immunol2022
34968849Design of a naphthalimide-based probe for acrolein detection in foods and cells.J Hazard Mater2022
33597588CD4+â¿¿T cells from children with active juvenile idiopathic arthritis show altered chromatin features associated with transcriptional abnormalities.Sci Rep2021
32730263Broadening our understanding of the genetics of Juvenile Idiopathic Arthritis (JIA): Interrogation of three dimensional chromatin structures and genetic regulatory elements within JIA-associated risk loci.PLoS One2020
31780296Formation of di-cysteine acrolein adduct decreases cytotoxicity of acrolein by ROS alleviation and apoptosis intervention.J Hazard Mater2020
33059716Classification models using circulating neutrophil transcripts can detect unruptured intracranial aneurysm.J Transl Med2020
33156839Whole blood transcriptome biomarkers of unruptured intracranial aneurysm.PLoS One2020
32793937The scavenging capacity of γ-aminobutyric acid for acrolein and the cytotoxicity of the formed adduct.Food Funct2020
30300775Adducts formed during protein digestion decreased the toxicity of five carbonyl compounds against Caco-2 cells.J Hazard Mater2019
31666072Epigenetic landscapes suggest that genetic risk for intracranial aneurysm operates on the endothelium.BMC Med Genomics2019
31706344The feasibility of developing biomarkers from peripheral blood mononuclear cell RNAseq data in children with juvenile idiopathic arthritis using machine learning approaches.Arthritis Res Ther2019
29941318RNA sequencing data from neutrophils of patients with cystic fibrosis reveals potential for developing biomarkers for pulmonary exacerbations.J Cyst Fibros2019
31299993Plasma exosomes from children with juvenile dermatomyositis are taken up by human aortic endothelial cells and are associated with altered gene expression in those cells.Pediatr Rheumatol Online J2019
29342213Circulating neutrophil transcriptome may reveal intracranial aneurysm signature.PLoS One2018
29800761Soluble inflammatory mediators induce transcriptional re-organization that is independent of dna methylation changes in cultured human chorionic villous trophoblasts.J Reprod Immunol2018
30593281Biomarkers from circulating neutrophil transcriptomes have potential to detect unruptured intracranial aneurysms.J Transl Med2018
30619322Using Chromatin Architecture to Understand the Genetics and Transcriptomics of Juvenile Idiopathic Arthritis.Front Immunol2018
29773851Modeling Transcriptional Rewiring in Neutrophils Through the Course of Treated Juvenile Idiopathic Arthritis.Sci Rep2018
28572608Genetic insights into juvenile idiopathic arthritis derived from deep whole genome sequencing.Sci Rep2017
28288683Chromatin landscapes and genetic risk for juvenile idiopathic arthritis.Arthritis Res Ther2017
26888867Mapping of Variable DNA Methylation Across Multiple Cell Types Defines a Dynamic Regulatory Landscape of the Human Genome.G3 (Bethesda)2016
27906046Chromatin landscapes and genetic risk in systemic lupus.Arthritis Res Ther2016
27271962Complexity and Specificity of the Neutrophil Transcriptomes in Juvenile Idiopathic Arthritis.Sci Rep2016
27388672Whole blood expression profiling from the TREAT trial: insights for the pathogenesis of polyarticular juvenile idiopathic arthritis.Arthritis Res Ther2016
27385437Limits of Peripheral Blood Mononuclear Cells for Gene Expression-Based Biomarkers in Juvenile Idiopathic Arthritis.Sci Rep2016
25833190Disease-Associated Single-Nucleotide Polymorphisms From Noncoding Regions in Juvenile Idiopathic Arthritis Are Located Within or Adjacent to Functional Genomic Elements of Human Neutrophils and CD4+ T Cells.Arthritis Rheumatol2015
26497493Dynamic tracking of functional gene modules in treated juvenile idiopathic arthritis.Genome Med2015
26310571RNA sequencing from human neutrophils reveals distinct transcriptional differences associated with chronic inflammatory states.BMC Med Genomics2015
24782192Whole blood gene expression profiling predicts therapeutic response at six months in patients with polyarticular juvenile idiopathic arthritis.Arthritis Rheumatol2014
24000795Genomic characterization of remission in juvenile idiopathic arthritis.Arthritis Res Ther2013
19248118The meaning of clinical remission in polyarticular juvenile idiopathic arthritis: gene expression profiling in peripheral blood mononuclear cells identifies distinct disease states.Arthritis Rheum2009
19616846Ablation of Stat3 by siRNA alters gene expression profiles in JEG-3 cells: a systems biology approach.Placenta2009
19404961Gene expression profiling in neutrophils from children with polyarticular juvenile idiopathic arthritis.Arthritis Rheum2009
19236715Disease-associated pathophysiologic structures in pediatric rheumatic diseases show characteristics of scale-free networks seen in physiologic systems: implications for pathogenesis and treatment.BMC Med Genomics2009
16904741Soluble factors from LPS- and PHA-activated PBMC induce MAPK, Stat1 and Stat3 phosphorylation in primary cultures of human term placental trophoblasts: implications for infection and prematurity.Placenta2007
17567896Neutrophils: the forgotten cell in JIA disease pathogenesis.Pediatr Rheumatol Online J2007
17306030A dynamic model of gene expression in monocytes reveals differences in immediate/early response genes between adult and neonatal cells.J Inflamm (Lond)2007
16257052hCG Secretion in human choriocarcinoma JAR cells is MAPK but not Stat3 dependent: contributions of TNFalpha and IL-1beta to inflammation-induced hCG secretion.Placenta2006
17002793Evidence for chronic, peripheral activation of neutrophils in polyarticular juvenile rheumatoid arthritis.Arthritis Res Ther2006
15063633Gene expression arrays reveal a rapid return to normal homeostasis in immunologically-challenged trophoblast-like JAR cells.J Reprod Immunol2004
15331329Cord blood and adult T cells show different responses to C1q-bearing immune complexes.Cell Immunol2004
14979934Novel approaches to gene expression analysis of active polyarticular juvenile rheumatoid arthritis.Arthritis Res Ther2004
12519387T cell activation by soluble C1q-bearing immune complexes: implications for the pathogenesis of rheumatoid arthritis.Clin Exp Immunol2003
14638439Activated peripheral blood mononuclear cells induce p44/42 mitogen-activated protein kinase phosphorylation in trophoblast-like JAR cells.J Reprod Immunol2003
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Collaborators

James N Jarvis
Jacobs School of Medicine and Biomedical Sciences, University at Buffalo
Co-authored papers 42
Mark Barton Frank
Oklahoma Medical Research Foundation
Co-authored papers 14
Carol A Wallace
Seattle Children's Hospital, University of Washington
Co-authored papers 7
Ashley Sawle
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 3
Patrick M Gaffney
Co-authored papers 2
Ting Wang
Washington University School of Medicine
Co-authored papers 2
Xiaoyun Xing
Co-authored papers 2
Bo Zhang
Co-authored papers 1
Michael J Buck
Jacobs School of Medicine and Biomedical Sciences, University at Buffalo
Co-authored papers 1
Joseph F Costello
University of California san francisco
Co-authored papers 1
Nan Du
Institute for Solid State Physics, Friedrich Schiller University Jena
Co-authored papers 1
Tao Liu
Co-authored papers 1
Yufeng Shen
Columbia University
Co-authored papers 1
Jacqueline E Payton
Washington University School of Medicine.
Co-authored papers 1
Aidong Zhang (CM4AI)
University of Virginia
Co-authored papers 1
Release 1.2