Author details

Full Name

Ian A Blair

Affiliation

ORCID

Career Start Year

1977

Papers

405

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37773266	Chimeric kinase ALK induces expression of NAMPT and selectively depends on this metabolic enzyme to sustain its own oncogenic function.		2023
37759736	Cisplatin Dependent Secretion of Immunomodulatory High Mobility Group Box 1 (HMGB1) Protein from Lung Cancer Cells.		2023
37945602	Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples.	Nat Commun	2023
37717994	The androgen receptor.		2023
37891254	Quantification of human mature frataxin protein expression in nonhuman primate hearts after gene therapy.		2023
38063871	Frataxin analysis using triple quadrupole mass spectrometry: application to a large heterogeneous clinical cohort.		2023
35315913	Bcl-xL Enforces a Slow-Cycling State Necessary for Survival in the Nutrient-Deprived Microenvironment of Pancreatic Cancer.	Cancer Res	2022
36369506	Ruxolitinib and exemestane for estrogen receptor positive, aromatase inhibitor resistant advanced breast cancer.	npj Breast Cancer	2022
36016708	Frataxin controls ketone body metabolism through regulation of OXCT1.	PNAS Nexus	2022
35573317	Simultaneous Quantification of Mitochondrial Mature Frataxin and Extra-Mitochondrial Frataxin Isoform E in Friedreich's Ataxia Blood.	Frontiers in Neuroscience	2022
35922039	Characterization and Quantification of Oxidized High Mobility Group Box 1 Proteoforms Secreted from Hepatocytes by Toxic Levels of Acetaminophen.	Chemical Research in Toxicology	2022
36874369	Reappraisal of oxidized HMGB1 as a mediator and biomarker.		2022
35322126	DNA methylation in Friedreich ataxia silences expression of frataxin isoform E.	Sci Rep	2022
34844667	Glutamine deprivation triggers NAGK-dependent hexosamine salvage.	eLife	2021
33483516	Effects of systemic inflammation on relapse in early breast cancer.	NPJ Breast Cancer	2021
33991687	Reverse Phase Protein Array Reveals Correlation of Retinoic Acid Metabolism With Cardiomyopathy in Friedreich's Ataxia.	Molecular and Cellular Proteomics	2021
34029057	Efficient Labeling of Native Human IgG by Proximity-Based Sortase-Mediated Isopeptide Ligation.	Bioconjug Chem	2021
34244212	Cholesterol Auxotrophy as a Targetable Vulnerability in Clear Cell Renal Cell Carcinoma.	Cancer Discov	2021
33159852	Upregulation of Antioxidant Capacity and Nucleotide Precursor Availability Suffices for Oncogenic Transformation.	Cell Metab	2021
31416743	The proteome and its dynamics: A missing piece for integrative multi-omics in schizophrenia.	Schizophr Res	2020
31815742	Gut microbiota modulate dendritic cell antigen presentation and radiotherapy-induced antitumor immune response.	J Clin Invest	2020
31758918	Cervicovaginal fluid proteomic analysis to identify potential biomarkers for preterm birth.	American Journal of Obstetrics and Gynecology	2020
32703873	Chaperone-mediated autophagy regulates the pluripotency of embryonic stem cells.	Science	2020
32978498	Extra-mitochondrial mouse frataxin and its implications for mouse models of Friedreich's ataxia.	Scientific Reports	2020
32966340	Autophagy mitigates ethanol-induced mitochondrial dysfunction and oxidative stress in esophageal keratinocytes.	PLoS One	2020
32505743	Impaired Redox and Protein Homeostasis as Risk Factors and Therapeutic Targets in Toxin-Induced Biliary Atresia.	Gastroenterology	2020
33326785	Lactate Limits T Cell Proliferation via the NAD(H) Redox State.	Cell Reports	2020
31519066	Voriconazole enhances UV-induced DNA damage by inhibiting catalase and promoting oxidative stress.	Exp Dermatol	2020
31347076	Analytical Methods for Mass Spectrometry-Based Metabolomics Studies.	Advances in Experimental Medicine and Biology	2019
31663337	Correction to "Role of Human Aldo-Keto Reductases in the Metabolic Activation of the Carcinogenic Air Pollutant 3-Nitrobenzanthrone".	Chemical Research in Toxicology	2019
31613099	In Vitro Biotransformation of the Nrf2 Activator Bardoxolone: Formation of an Epoxide Metabolite That Undergoes Two Novel Glutathione-Mediated Metabolic Pathways: Epoxide Reduction and Oxidative Elimination of Nitrile Moiety.	Chemical Research in Toxicology	2019
30281805	Impact of route of administration on genotoxic oestrogens concentrations using oral vs transdermal oestradiol in girls with Turner syndrome.	Clinical Endocrinology	2019
30656180	Safety, pharmacodynamics, and potential benefit of omaveloxolone in Friedreich ataxia.	Annals of Clinical and Translational Neurology	2019
31285843	The current state of biomarker research for Friedreich's ataxia: a report from the 2018 FARA biomarker meeting.	Future Science OA	2019
31279523	Evaluation of antibodies for western blot analysis of frataxin protein isoforms.	Journal of Immunological Methods	2019
30862686	Metabolic Detection of Bruton's Tyrosine Kinase Inhibition in Mantle Cell Lymphoma Cells.	Molecular Cancer Research	2019
30676739	Correction to Liquid Chromatography-High Resolution Mass Spectrometry Analysis of Platelet Frataxin as a Protein Biomarker for the Rare Disease Friedreich's Ataxia.	Analytical Chemistry	2019
29577272	Effect of a tissue selective estrogen complex on breast cancer: Role of unique properties of conjugated equine estrogen.	International Journal of Cancer	2018
30406992	Role of Human Aldo-Keto Reductases in the Metabolic Activation of the Carcinogenic Air Pollutant 3-Nitrobenzanthrone.	Chemical Research in Toxicology	2018
30451920	Characterization of a new N-terminally acetylated extra-mitochondrial isoform of frataxin in human erythrocytes.	Scientific Reports	2018
30201937	Gestational Diabetes Alters the Metabolomic Profile in 2nd Trimester Amniotic Fluid in a Sex-Specific Manner.	International Journal of Molecular Sciences	2018
30279592	Effect of Differences in Metabolic Activity of Melanoma Models on Response to Lonidamine plus Doxorubicin.	Scientific Reports	2018
29675169	Bioorthogonal pro-metabolites for profiling short chain fatty acylation.	Chemical Science	2018
29674640	The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations.	Sci Rep	2018
29272104	Liquid Chromatography-High Resolution Mass Spectrometry Analysis of Platelet Frataxin as a Protein Biomarker for the Rare Disease Friedreich's Ataxia.	Analytical Chemistry	2018
29447225	Low apolipoprotein A-I levels in Friedreich's ataxia and in frataxin-deficient cells: Implications for therapy.	PLoS ONE	2018
29669281	Differential Reliance on Lipid Metabolism as a Salvage Pathway Underlies Functional Differences of T Cell Subsets in Poor Nutrient Environments.	Cell Reports	2018
29754953	Arginase 2 Suppresses Renal Carcinoma Progression via Biosynthetic Cofactor Pyridoxal Phosphate Depletion and Increased Polyamine Toxicity.	Cell Metab	2018
29301865	Analysis of HETEs in human whole blood by chiral UHPLC-ECAPCI/HRMS.	J Lipid Res	2018
29610310	Microbes vs. chemistry in the origin of the anaerobic gut lumen.	Proc Natl Acad Sci U S A	2018