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Author Details

Bryan D Bryson
Massachusetts Institute of Technology, USA The Ragon Institute of MGH
2012
39
15
PMIDPaper TitleJournal TitlePublished Year
36778460Tregs constrain CD8<sup>+</sup> T cell priming required for curative intratumorally anchored anti-4-1BB immunotherapy.bioRxiv2023
37963018Single-cell analysis reveals a weak macrophage subpopulation response to Mycobacterium tuberculosis infection.Cell Rep2023
37502895Protective intravenous BCG vaccination induces enhanced immune signaling in the airways.bioRxiv2023
37289807Contrastive learning in protein language space predicts interactions between drugs and protein targets.Proc Natl Acad Sci U S A2023
37439558TLR2 is non-redundant in the population and subpopulation responses to <i>Mycobacterium tuberculosis</i> in macrophages and <i>in vivo</i>.mSystems2023
37073954Immunopeptidomics reveals determinants of Mycobacterium tuberculosis antigen presentation on MHC class I.Elife2023
37228375Maternal HIV infection drives altered placental <i>Mtb</i>-specific antibody transfer.Front Microbiol2023
36747859Compressed phenotypic screens for complex multicellular models and high-content assays.bioRxiv2023
35038923CRISPR Interference Reveals That All-<i>Trans</i>-Retinoic Acid Promotes Macrophage Control of Mycobacterium tuberculosis by Limiting Bacterial Access to Cholesterol and Propionyl Coenzyme A.mBio2022
35590143JAK inhibition in a patient with a STAT1 gain-of-function variant reveals STAT1 dysregulation as a common feature of aplastic anemia.Med2022
35654811Artificial neural networks enable genome-scale simulations of intracellular signaling.Nat Commun2022
35483355Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control.Immunity2022
36454758MEK inhibition enhances presentation of targetable MHC-I tumor antigens in mutant melanomas.Proc Natl Acad Sci U S A2022
35867799TREM2 macrophages induced by human lipids drive inflammation in acne lesions.Sci Immunol2022
35014856Predicting the mutational drivers of future SARS-CoV-2 variants of concern.Sci Transl Med2022
33446556Learning the language of viral evolution and escape.Science2021
34606245Biosynthetic Glycan Labeling.J Am Chem Soc2021
34779416Unlocking the complexity of HIV and Mycobacterium tuberculosis coinfection.J Clin Invest2021
34179732Dissecting the common and compartment-specific features of COVID-19 severity in the lung and periphery with single-cell resolution.iScience2021
34342538Leveraging Immunopeptidomics To Study and Combat Infectious Disease.mSystems2021
34235657Flow Cytometry Analysis of Mycobacteria and Mycobacteria-Infected Immune Cells.Methods Mol Biol2021
33408238mSphere of Influence: the Complexity of Interferon Gamma-Mediated Pathogen Control.mSphere2021
33065027Leveraging Uncertainty in Machine Learning Accelerates Biological Discovery and Design.Cell Syst2020
31133636Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis.Nat Commun2019
33523202Uncovering complex molecular networks in host-pathogen interactions using systems biology.Emerg Top Life Sci2019
31176620Geometric Sketching Compactly Summarizes the Single-Cell Transcriptomic Landscape.Cell Syst2019
31235553IL-1β Induces the Rapid Secretion of the Antimicrobial Protein IL-26 from Th17 Cells.J Immunol2019
31061482Efficient integration of heterogeneous single-cell transcriptomes using Scanorama.Nat Biotechnol2019
29732401Posttranslational modification of a histone-like protein regulates phenotypic resistance to isoniazid in mycobacteria.Sci Adv2018
28192419Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput.Nat Methods2017
27081872RNA Extraction from a Mycobacterium under Ultrahigh Electric Field Intensity in a Microfluidic Device.Anal Chem2016
25611466Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization.PLoS Pathog2015
25978619Quantitative Profiling of Lysine Acetylation Reveals Dynamic Crosstalk between Receptor Tyrosine Kinases and Lysine Acetylation.PLoS One2015
25641834Engineered bromodomains to explore the acetylproteome.Proteomics2015
25142464SirT1 is required in the male germ cell for differentiation and fecundity in mice.Development2014
23500044Computer aided manual validation of mass spectrometry-based proteomic data.Methods2013
23728299The bromodomain protein Brd4 insulates chromatin from DNA damage signalling.Nature2013
22735337Signaling for death: tyrosine phosphorylation in the response to glucose deprivation.Mol Syst Biol2012
22964225Molecular characterization of EGFR and EGFRvIII signaling networks in human glioblastoma tumor xenografts.Mol Cell Proteomics2012
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Collaborators

Forest M White
Massachusetts Institute of Technology
Co-authored papers 10
Bonnie Berger
Massachusetts Institute of Technology
Co-authored papers 7
Alex K Shalek
Institute for Medical Engineering & Science, Massachusetts Institute of Technology
Co-authored papers 5
Brian Hie
Stanford University
Co-authored papers 5
JoAnne L Flynn
Co-authored papers 3
William C Hahn
Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute
Co-authored papers 2
Galit Alter
Co-authored papers 2
Matteo Pellegrini
Co-authored papers 2
Jann N Sarkaria
Co-authored papers 1
David M Sabatini
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
Co-authored papers 1
Alexander A Merleev
Co-authored papers 1
John Leszyk
Co-authored papers 1
Benjamin DeMeo
Harvard University
Co-authored papers 1
Amalio Telenti
Vir Biotechnology Inc.
Co-authored papers 1
Michael C Maher
Vir Biotechnology Inc.
Co-authored papers 1
Jeremy M Rock
The Rockefeller University
Co-authored papers 1
Rahul Satija
Center for Genomics and Systems Biology, New York University
Co-authored papers 1
Laura L Kiessling
Massachusetts Institute of Technology
Co-authored papers 1
James A Wells
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 1
Jaime H Cheah
Johns Hopkins University School of Medicine
Co-authored papers 1
James E Bradner
Co-authored papers 1
Jose Ordovas-Montanes
Co-authored papers 1
Hyunghoon Cho
Broad Institute of MIT and Harvard, Massachusetts Institute of Technology, Stanford University, Yale University
Co-authored papers 1
Lam C Tsoi
Co-authored papers 1
Douglas S Kwon
Ragon Institute of MGH
Co-authored papers 1
Jonathan S Gootenberg
McGovern Institute for Brain Research at MIT Massachusetts Institute of Technology
Co-authored papers 1
Sergei L Kosakovsky Pond
Co-authored papers 1
Anne E Carpenter
Broad Institute of MIT and Harvard
Co-authored papers 1
Heidi L Rehm
The Broad Institute of MIT and Harvard
Co-authored papers 1
Aviv Regev
Broad Institute of MIT and Harvard
Co-authored papers 1
Release 1.2