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Author Details

Jason W Locasale
Duke University
2007
204
76
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37931287Vitamin B6 Competition in the Tumor Microenvironment Hampers Antitumor Functions of NK Cells.Cancer Discov2024
36640341Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation.Cell Rep2023
38081847GRAF1 integrates PINK1-Parkin signaling and actin dynamics to mediate cardiac mitochondrial homeostasis.Nat Commun2023
37517954Methionine restriction and antitumor immunity.Trends Cancer2023
37847509Delineating a Role for Methionine Metabolism in Colorectal Cancer.Cancer Res2023
38045360Methionine availability influences essential H3K36me3 dynamics during cell differentiation.bioRxiv2023
37192295Metabolic adaptation to tyrosine kinase inhibition in leukemia stem cells.Blood2023
37020039Chronic hypoxia favours adoption to a castration-resistant cell state in prostate cancer.Oncogene2023
37380809Lysine metabolism at the nexus of crotonylation and tumor immunity.Cell Res2023
36803962Nucleotide metabolism is linked to cysteine availability.J Biol Chem2023
34911787Integrated Metabolic Profiling and Transcriptional Analysis Reveals Therapeutic Modalities for Targeting Rapidly Proliferating Breast Cancers.Cancer Res2022
35799202<sup>13</sup>C tracer analysis suggests extensive recycling of endogenous CO<sub>2</sub> in vivo.Cancer Metab2022
35697798MNK2 deficiency potentiates β-cell regeneration via translational regulation.Nat Chem Biol2022
35859173Sestrin mediates detection of and adaptation to low-leucine diets in Drosophila.Nature2022
36100671Author Correction: Sestrin mediates detection of and adaptation to low-leucine diets in Drosophila.Nature2022
36062923Diet and Exercise in Cancer Metabolism.Cancer Discov2022
33446543Targeting metabolism to influence aging.Science2021
33522109Metabolomics: insights into plant-based diets.EMBO Mol Med2021
33649228Metabolic supervision by PPIP5K, an inositol pyrophosphate kinase/phosphatase, controls proliferation of the HCT116 tumor cell line.Proc Natl Acad Sci U S A2021
33510167Cellular stress signaling activates type-I IFN response through FOXO3-regulated lamin posttranslational modification.Nat Commun2021
33730592SGK1 signaling promotes glucose metabolism and survival in extracellular matrix detached cells.Cell Rep2021
33667809Epigenomic links from metabolism-methionine and chromatin architecture.Curr Opin Chem Biol2021
33753479A glutaminase isoform switch drives therapeutic resistance and disease progression of prostate cancer.Proc Natl Acad Sci U S A2021
33558372Targeting In Vivo Metabolic Vulnerabilities of Th2 and Th17 Cells Reduces Airway Inflammation.J Immunol2021
35083422Rethinking the bioavailability and cellular transport properties of S-adenosylmethionine.Cell Stress2021
34609963The TGF-β/HDAC7 axis suppresses TCA cycle metabolism in renal cancer.JCI Insight2021
34686867Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity.Nat Immunol2021
34414571Metabolic decisions in development and disease-a Keystone Symposia report.Ann N Y Acad Sci2021
34102853PKM1 Exerts Critical Roles in Cardiac Remodeling Under Pressure Overload in the Heart.Circulation2021
33982817Metabolomics in cancer research and emerging applications in clinical oncology.CA Cancer J Clin2021
32511475Cooperative virus propagation in COVID-19 transmission.medRxiv2020
32058969Exposure of Pancreatic β-Cells to Excess Glucose Results in Bimodal Activation of mTORC1 and mTOR-Dependent Metabolic Acceleration.iScience2020
32058966Dynamic <sup>13</sup>C Flux Analysis Captures the Reorganization of Adipocyte Glucose Metabolism in Response to Insulin.iScience2020
31901298Histone Lactylation: A New Role for Glucose Metabolism.Trends Biochem Sci2020
32023442Dietary Methionine in T Cell Biology and Autoimmune Disease.Cell Metab2020
31748414Evolved resistance to partial GAPDH inhibition results in loss of the Warburg effect and in a different state of glycolysis.J Biol Chem2020
31954223Metabolic regulation of epigenetic remodeling in immune cells.Curr Opin Biotechnol2020
33157016The Molecular Link from Diet to Cancer Cell Metabolism.Mol Cell2020
33294794Erratum: Dynamic <sup>13</sup>C Flux Analysis Captures the Reorganization of Adipocyte Glucose Metabolism in Response to Insulin.iScience2020
33230181SUCLA2 mutations cause global protein succinylation contributing to the pathomechanism of a hereditary mitochondrial disease.Nat Commun2020
32719540A spoonful of DHAP keeps mTORC1 running on sugars.Nat Metab2020
32691018NRF2 activation promotes the recurrence of dormant tumour cells through regulation of redox and nucleotide metabolism.Nat Metab2020
32690540Identification of BBOX1 as a Therapeutic Target in Triple-Negative Breast Cancer.Cancer Discov2020
32770044HNF4α regulates sulfur amino acid metabolism and confers sensitivity to methionine restriction in liver cancer.Nat Commun2020
32961109Quantitative Analysis of the Physiological Contributions of Glucose to the TCA Cycle.Cell Metab2020
32908249The evolving metabolic landscape of chromatin biology and epigenetics.Nat Rev Genet2020
32928875Teleological role of L-2-hydroxyglutarate dehydrogenase in the kidney.Dis Model Mech2020
33020660Disturbed mitochondrial dynamics in CD8<sup>+</sup> TILs reinforce T cell exhaustion.Nat Immunol2020
32978605Author Correction: The evolving metabolic landscape of chromatin biology and epigenetics.Nat Rev Genet2020
32504556The Molecular Link from Diet to Cancer Cell Metabolism.Mol Cell2020
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Collaborators

Lewis C Cantley
Co-authored papers 23
Ziwei Dai
Southern University of Science and Technology
Co-authored papers 22
Matthew D Hirschey
Duke Molecular Physiology Institute, Duke University School of Medicine
Co-authored papers 7
Costas A Lyssiotis
Co-authored papers 6
Kris C Wood
Duke University
Co-authored papers 5
Zheng Ser
Institute of Molecular and Cell Biology
Co-authored papers 5
Lee W Jones
Memorial Sloan Kettering Cancer Center
Co-authored papers 4
Yingming Zhao
Co-authored papers 4
Evan Dale Abel
Co-authored papers 3
Charles M Perou
Co-authored papers 3
Cheng Fan
Co-authored papers 3
Aguirre A de Cubas
Co-authored papers 3
Katherine R Singleton
Duke University
Co-authored papers 3
Donald P McDonnell
Co-authored papers 3
Christian M Metallo
Massachusetts Institute of Technology
Co-authored papers 3
Ernst Lengyel
University of Chicago
Co-authored papers 3
Wendy Kimryn Rathmell
Co-authored papers 3
Gregory Stephanopoulos
Massachusetts Institute of Technology
Co-authored papers 3
Norbert Perrimon
Co-authored papers 3
Joshua D Rabinowitz
Lewis Sigler Institute for Integrative Genomics, Princeton University
Co-authored papers 3
Nicholas P Restifo
National Cancer Institute, National Institutes of Health (NIH)
Co-authored papers 2
Andrew D Wells
Center for Spatial and Functional Genomics, Children's Hospital of Philadelphia
Co-authored papers 2
Geoffrey Neale
St. Jude Children's Research Hospital
Co-authored papers 2
Markus Ralser
Charite - Universitatsmedizin Berlin
Co-authored papers 2
Gray R Anderson
Duke University
Co-authored papers 2
Lorin Crawford
Center for Computational Molecular Biology, Brown University
Co-authored papers 2
Jeremy M Simon
University of North Carolina
Co-authored papers 2
David M Sabatini
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
Co-authored papers 2
Genevi??ve Deblois
Institute for Research in Immunology and Cancer (IRIC), University of Montreal
Co-authored papers 2
Seyed Ali Madani Tonekaboni
Princess Margaret Cancer Research Centre
Co-authored papers 2
Release 1.2