Skip to Main Content

Author Details

Baggavalli P Somesh
Connexios Life Sciences Pvt Ltd
2000
23
15
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
30426790Effect of endosulfan and bisphenol A on the expression of SUMO and UBC9.Drug Chem Toxicol2020
24460834CNX-012-570, a direct AMPK activator provides strong glycemic and lipid control along with significant reduction in body weight; studies from both diet-induced obese mice and db/db mice models.Cardiovasc Diabetol2014
25598841Developing an in vitro screening assay platform for evaluation of antifibrotic drugs using precision-cut liver slices.Fibrogenesis Tissue Repair2014
24974801Activation of GPR40 attenuates chronic inflammation induced impact on pancreatic β-cells health and function.BMC Cell Biol2014
25098735A novel 11β-hydroxysteroid dehydrogenase type1 inhibitor CNX-010-49 improves hyperglycemia, lipid profile and reduces body weight in diet induced obese C57B6/J mice with a potential to provide cardio protective benefits.BMC Pharmacol Toxicol2014
25143786CNX-013-B2, a unique pan tissue acting rexinoid, modulates several nuclear receptors and controls multiple risk factors of the metabolic syndrome without risk of hypertriglyceridemia, hepatomegaly and body weight gain in animal models.Diabetol Metab Syndr2014
25186493A novel GPR40 agonist, CNX-011-67, suppresses glucagon secretion in pancreatic islets under chronic glucolipotoxic conditions in vitro.BMC Res Notes2014
24892004Inhibition of neutral sphingomyelinases in skeletal muscle attenuates fatty-acid induced defects in metabolism and stress.Springerplus2014
24936385Integrated analysis of chronic lipotoxicity on muscle metabolism and stress and its reversal by antioxidants.Springerplus2014
24666736CNX-011-67, a novel GPR40 agonist, enhances glucose responsiveness, insulin secretion and islet insulin content in n-STZ rats and in islets from type 2 diabetic patients.BMC Pharmacol Toxicol2014
23692921Treatment with CNX-011-67, a novel GPR40 agonist, delays onset and progression of diabetes and improves beta cell preservation and function in male ZDF rats.BMC Pharmacol Toxicol2013
23815372Chronic glucolipotoxic conditions in pancreatic islets impair insulin secretion due to dysregulated calcium dynamics, glucose responsiveness and mitochondrial activity.BMC Cell Biol2013
19920177Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation.Proc Natl Acad Sci U S A2009
17418786Communication between distant sites in RNA polymerase II through ubiquitylation factors and the polymerase CTD.Cell2007
16950926RacG regulates morphology, phagocytosis, and chemotaxis.Eukaryot Cell2006
17004322Dictyostelium RacH regulates endocytic vesicular trafficking and is required for localization of vacuolin.Traffic2006
15563457Interaction of Fcp1 phosphatase with elongating RNA polymerase II holoenzyme, enzymatic mechanism of action, and genetic interaction with elongator.J Biol Chem2005
15960978Multiple mechanisms confining RNA polymerase II ubiquitylation to polymerases undergoing transcriptional arrest.Cell2005
12426103Genomic organization and expression profile of the small GTPases of the RhoBTB family in human and mouse.Gene2002
12952072Signal transduction pathways regulated by Rho GTPases in Dictyostelium.J Muscle Res Cell Motil2002
12198156Defects in cytokinesis, actin reorganization and the contractile vacuole in cells deficient in RhoGDI.EMBO J2002
11150671A Mycobacterium smegmatis gyrase B specific monoclonal antibody reveals association of gyrase A and B subunits in the cell.FEMS Microbiol Lett2001
11123935Biochemical characterization of the intracellular domain of the human guanylyl cyclase C receptor provides evidence for a catalytically active homotrimer.Biochemistry2000
  • 1 - 23 of 23

Recommended Authors

Institut Curie, PSL Research University
Career Start Year 2011
Number of shared co-authors 0
University of Washington
Career Start Year 2008
Number of shared co-authors 0
University of Pittsburgh
Career Start Year 2006
Number of shared co-authors 0
Guangdong Medical University
Career Start Year 2006
Number of shared co-authors 1
Joslin Diabetes Center, Harvard Medical School
Career Start Year 2005
Number of shared co-authors 0
West China Hospital, Sichuan University
Career Start Year 2005
Number of shared co-authors 1
The University of Sydney
Career Start Year 2005
Number of shared co-authors 0
McGill Research Centre for Studies in Aging
Career Start Year 2003
Number of shared co-authors 0
Institut Necker-Enfants Malades (INEM)
Career Start Year 2002
Number of shared co-authors 1
Cumming School of Medicine, University of Calgary, 0 Hospital Drive NW
Career Start Year 2000
Number of shared co-authors 0
Ningbo First Hospital, Zhejiang University
Career Start Year 2000
Number of shared co-authors 0
University of Dundee
Career Start Year 1999
Number of shared co-authors 1
Meilahti Clinical Proteomics Core Facility, University of Helsinki
Career Start Year 1999
Number of shared co-authors 0
University of Copenhagen
Career Start Year 1998
Number of shared co-authors 1
Nanyang First People's Hospital Affiliated to Henan University
Career Start Year 1998
Number of shared co-authors 0
Dasman Diabetes Institute
Career Start Year 1998
Number of shared co-authors 0
Diabetes Center, University of California san francisco
Career Start Year 1996
Number of shared co-authors 1
Institut Curie, PSL Research University
Career Start Year 1996
Number of shared co-authors 0
National Institute of Biological Sciences
Career Start Year 1995
Number of shared co-authors 0
Lunenfeld-Tanenbaum Research Institute
Career Start Year 1994
Number of shared co-authors 1
Fudan University Shanghai Cancer Center
Career Start Year 1993
Number of shared co-authors 1
The University of Hong Kong
Career Start Year 1991
Number of shared co-authors 1
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
Career Start Year 1990
Number of shared co-authors 3
University of California San Diego
Career Start Year 1988
Number of shared co-authors 0
Inc. Research Triangle Park
Career Start Year 1987
Number of shared co-authors 0
Chungnam National University
Career Start Year 1987
Number of shared co-authors 1
Harvard Medical School
Career Start Year 1981
Number of shared co-authors 1
Cambridge Institute for Medical Research, University of Cambridge
Career Start Year 1979
Number of shared co-authors 1
University of Colorado School of Medicine
Career Start Year 1978
Number of shared co-authors 0
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
Career Start Year 1976
Number of shared co-authors 0

Collaborators

Panum Institute, University of Copenhagen
Co-authored papers 4
Co-authored papers 2
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Neuroscience Institute, NYU Grossman School of Medicine
Co-authored papers 2
Expres2ion Biotechnologies
Co-authored papers 2
Cancer Research UK London Research Institute
Co-authored papers 2
University of California San Francisco
Co-authored papers 1
College Street, University of Toronto
Co-authored papers 1
University of British Columbia
Co-authored papers 1
Co-authored papers 1