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Author Details

Luping Lin
Incyte Research Institute, Incyte Corporation
2010
23
15
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36923909Discovery of Orally Bioavailable FGFR2/FGFR3 Dual Inhibitors via Structure-Guided Scaffold Repurposing Approach.ACS Med Chem Lett2023
37124061Tumor Necrosis Factor-<i>α</i> Promotes the Tumorigenesis, Lymphangiogenesis, and Lymphatic Metastasis in Cervical Cancer via Activating VEGFC-Mediated AKT and ERK Pathways.Mediators Inflamm2023
37206585Prognostic values of regulatory T cells (Tregs) and Treg-related genes in gastric cancer.Cent Eur J Immunol2023
35254416Characterization of INCB086550: A Potent and Novel Small-Molecule PD-L1 Inhibitor.Cancer Discov2022
35571075Tissue Distribution, Excretion, and Interaction With Human Serum Albumin of Total Bioflavonoid Extract From <i>Selaginella doederleinii</i>.Front Pharmacol2022
35859885Discovery of Novel Pyrazolopyrimidines as Potent, Selective, and Orally Bioavailable Inhibitors of ALK2.ACS Med Chem Lett2022
36356320Discovery of Potent and Selective Inhibitors of Wild-Type and Gatekeeper Mutant Fibroblast Growth Factor Receptor (FGFR) 2/3.J Med Chem2022
34310658DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junction.PLoS Pathog2021
32452420Antiviral activity of lycorine against Zika virus in vivo and in vitro.Virology2020
31380586Interferon alpha treatment leads to a high rate of hepatitis B surface antigen seroconversion in Chinese children with chronic hepatitis B.J Viral Hepat2019
31725752Molecular epidemiological characteristics of dengue virus carried by 34 patients in Guangzhou in 2018.PLoS One2019
28287179Novel computational method for predicting polytherapy switching strategies to overcome tumor heterogeneity and evolution.Sci Rep2017
27834212Preclinical efficacy of a RAF inhibitor that evades paradoxical MAPK pathway activation in protein kinase BRAF-mutant lung cancer.Proc Natl Acad Sci U S A2016
25665005The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies.Nat Genet2015
26301689RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer.Nat Med2015
27308535The Hippo effector YAP regulates the response of cancer cells to MAPK pathway inhibitors.Mol Cell Oncol2015
25843712NF-κB-activating complex engaged in response to EGFR oncogene inhibition drives tumor cell survival and residual disease in lung cancer.Cell Rep2015
24550319Mapping the molecular determinants of BRAF oncogene dependence in human lung cancer.Proc Natl Acad Sci U S A2014
22829656Effects of cancer-associated EPHA3 mutations on lung cancer.J Natl Cancer Inst2012
22970367Mechanisms of Resistance to Epidermal Growth Factor Receptor Inhibitors and Novel Therapeutic Strategies to Overcome Resistance in NSCLC Patients.Chemother Res Pract2012
22751098Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer.Nat Genet2012
21825014Resuscitating cancer immunosurveillance: selective stimulation of DLL1-Notch signaling in T cells rescues T-cell function and inhibits tumor growth.Cancer Res2011
20068176Targeting specific regions of the Notch3 ligand-binding domain induces apoptosis and inhibits tumor growth in lung cancer.Cancer Res2010
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Collaborators

Trever G Bivona
University of California san francisco
Co-authored papers 9
Victor Olivas
University of California san francisco
Co-authored papers 7
Elton Chan
University of California san francisco
Co-authored papers 5
Saurabh Asthana
University of California San Francisco
Co-authored papers 5
Evangelos Pazarentzos
University of California san francisco
Co-authored papers 4
Dana S Neel
Stanford University School of Medicine
Co-authored papers 4
Collin M Blakely
University of California san francisco
Co-authored papers 3
Eric A Collisson
University of California san francisco
Co-authored papers 3
Jenny Jiacheng Yan
Helen Diller Comprehensive Cancer Center, University of California san francisco
Co-authored papers 3
Sourav Bandyopadhyay
University of California San Francisco
Co-authored papers 2
Lisa Truong
Incyte Research Institute, Incyte Corporation
Co-authored papers 2
Matthew A Gubens
University of California san francisco
Co-authored papers 2
Charles M Rudin
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Barry S Taylor
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Gorjan Hrustanovic
University of California san francisco
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Jose Miguel Sanchez
Co-authored papers 1
Charles L Sawyers
Memorial Sloan Kettering Cancer Center
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Timothy R Fouts
Profectus BioSciences Inc.
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Marc C Deller
Incyte Corporation
Co-authored papers 1
Jeffrey R Johnson
Gladstone Institutes
Co-authored papers 1
Jennifer A Wargo
Co-authored papers 1
Thomas LaFramboise
Co-authored papers 1
Maria M Martins
Stanford University
Co-authored papers 1
Irena Tan
Co-authored papers 1
Kathryn Bobb
Profectus BioSciences Inc.
Co-authored papers 1
David M Jablons
University of California, USA Cardiovascular Research Institute san francisco
Co-authored papers 1
Jeffrey Meshulam
Co-authored papers 1
Marc Ladanyi
Memorial Sloan Kettering Cancer Center
Co-authored papers 1
Billy W Newton
University of California San Francisco
Co-authored papers 1
Release 1.2