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Author Details

David T Auble
University of Virginia
1986
58
27
PMIDPaper TitleJournal TitlePublished Year
37568218Globally elevated levels of histone H3 lysine 9 trimethylation in early infancy are associated with poor growth trajectory in Bangladeshi children.Clin Epigenetics2023
37546819Genome-scale chromatin interaction dynamic measurements for key components of the RNA Pol II general transcription machinery.bioRxiv2023
37881559Transcriptional Profile of Exercise-Induced Protection Against Relapse to Cocaine Seeking in a Rat Model.Biol Psychiatry Glob Open Sci2023
34565452Histone H3 lysine 27 acetylation profile undergoes two global shifts in undernourished children and suggests altered one-carbon metabolism.Clin Epigenetics2021
33489883MYBL2-Driven Transcriptional Programs Link Replication Stress and Error-prone DNA Repair With Genomic Instability in Lung Adenocarcinoma.Front Oncol2021
30649478Conformational changes and catalytic inefficiency associated with Mot1-mediated TBP-DNA dissociation.Nucleic Acids Res2019
29682595An Improved Method for Measuring Chromatin-binding Dynamics Using Time-dependent Formaldehyde Crosslinking.Bio Protoc2018
30420518Histone H3 lysine 4 methylation signature associated with human undernutrition.Proc Natl Acad Sci U S A2018
30289385Crystal structure of the full Swi2/Snf2 remodeler Mot1 in the resting state.Elife2018
28051102RNA synthesis is associated with multiple TBP-chromatin binding events.Sci Rep2017
28972159Second-generation method for analysis of chromatin binding with formaldehyde-cross-linking kinetics.J Biol Chem2017
28665995Transcriptomes of six mutants in the Sen1 pathway reveal combinatorial control of transcription termination across the Saccharomyces cerevisiae genome.PLoS Genet2017
27255709Molecular Mechanism of Mot1, a TATA-binding Protein (TBP)-DNA Dissociating Enzyme.J Biol Chem2016
27226635The Modifier of Transcription 1 (Mot1) ATPase and Spt16 Histone Chaperone Co-regulate Transcription through Preinitiation Complex Assembly and Nucleosome Organization.J Biol Chem2016
26258880Structural basis for recognition and remodeling of the TBP:DNA:NC2 complex by Mot1.Elife2015
26354429Formaldehyde crosslinking: a tool for the study of chromatin complexes.J Biol Chem2015
25118072An evolving perspective about the origins of childhood undernutrition and nutritional interventions that includes the gut microbiome.Ann N Y Acad Sci2014
25448301Analysis of chromatin binding dynamics using the crosslinking kinetics (CLK) method.Methods2014
24091704Measuring chromatin interaction dynamics on the second time scale at single-copy genes.Science2013
22298788Two-step mechanism for modifier of transcription 1 (Mot1) enzyme-catalyzed displacement of TATA-binding protein (TBP) from DNA.J Biol Chem2012
21734658Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP.Nature2011
21907167Snf2/Swi2 ATPase structure and function.Biochim Biophys Acta2011
21658482One small step for Mot1; one giant leap for other Swi2/Snf2 enzymes?Biochim Biophys Acta2011
21685365An evolutionarily 'young' lysine residue in histone H3 attenuates transcriptional output in Saccharomyces cerevisiae.Genes Dev2011
20855454RNA synthesis precision is regulated by preinitiation complex turnover.Genome Res2010
21327160The Rad23 ubiquitin receptor, the proteasome and functional specificity in transcriptional control.Transcription2010
19038550The dynamic personality of TATA-binding protein.Trends Biochem Sci2009
19680226The Snf1 kinase and proteasome-associated Rad23 regulate UV-responsive gene expression.EMBO J2009
19098311TATA-binding protein variants that bypass the requirement for Mot1 in vivo.J Biol Chem2009
19052087Novel influenza virus NS1 antagonists block replication and restore innate immune function.J Virol2009
18606810Function and structural organization of Mot1 bound to a natural target promoter.J Biol Chem2008
18765812Regulation of TATA-binding protein dynamics in living yeast cells.Proc Natl Acad Sci U S A2008
17296733Regulation of rRNA synthesis by TATA-binding protein-associated factor Mot1.Mol Cell Biol2007
16541100Snf2/Swi2-related ATPase Mot1 drives displacement of TATA-binding protein by gripping DNA.EMBO J2006
15861138Mot1-mediated control of transcription complex assembly and activity.EMBO J2005
15078868Sir Antagonist 1 (San1) is a ubiquitin ligase.J Biol Chem2004
15226437The NEF4 complex regulates Rad4 levels and utilizes Snf2/Swi2-related ATPase activity for nucleotide excision repair.Mol Cell Biol2004
15192094Genome-wide analysis of ARS (autonomously replicating sequence) binding factor 1 (Abf1p)-mediated transcriptional regulation in Saccharomyces cerevisiae.J Biol Chem2004
12571241Mot1 regulates the DNA binding activity of free TATA-binding protein in an ATP-dependent manner.J Biol Chem2003
11880621Mot1 activates and represses transcription by direct, ATPase-dependent mechanisms.Proc Natl Acad Sci U S A2002
11296235MOT1-catalyzed TBP-DNA disruption: uncoupling DNA conformational change and role of upstream DNA.EMBO J2001
9858565Testing for DNA tracking by MOT1, a SNF2/SWI2 protein family member.Mol Cell Biol1999
10082549MOT1 can activate basal transcription in vitro by regulating the distribution of TATA binding protein between promoter and nonpromoter sites.Mol Cell Biol1999
10581240A new regulatory domain on the TATA-binding protein.EMBO J1999
9488487Cloning and biochemical characterization of TAF-172, a human homolog of yeast Mot1.Mol Cell Biol1998
9234740Molecular analysis of the SNF2/SWI2 protein family member MOT1, an ATP-driven enzyme that dissociates TATA-binding protein from DNA.Mol Cell Biol1997
7862117Analysis of the yeast transcription factor TFIIA: distinct functional regions and a polymerase II-specific role in basal and activated transcription.Mol Cell Biol1995
7958867Mot1, a global repressor of RNA polymerase II transcription, inhibits TBP binding to DNA by an ATP-dependent mechanism.Genes Dev1994
8491381An ATP-dependent inhibitor of TBP binding to DNA.Genes Dev1993
1320254Differential regulation of collagenase gene expression by retinoic acid receptors--alpha, beta and gamma.Nucleic Acids Res1992
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Collaborators

Stefan Bekiranov
University of Virginia
Co-authored papers 12
Steven Hahn
Fred Hutchinson Cancer Center
Co-authored papers 4
William A Petri
University of Virginia
Co-authored papers 3
Michael Brenowitz
Albert Einstein College of Medicine
Co-authored papers 2
James G McNally
Institute for Soft Matter and Functional Materials
Co-authored papers 2
Dongyan Wang
Guizhou Medical University
Co-authored papers 2
Henrik Molina
Co-authored papers 1
Roland Beckmann
University of Munich
Co-authored papers 1
Rong Li
University of Texas Health
Co-authored papers 1
Mark M Davis
Co-authored papers 1
Jeffrey A Ranish
Institute for Systems Biology
Co-authored papers 1
Justin T Reese
Lawrence Berkeley National Laboratory
Co-authored papers 1
Ann L Beyer
University of Virginia
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Jef D Boeke
Institute for Systems Genetics, NYU School of Medicine
Co-authored papers 1
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University of Wisconsin-Madison College of Letters and Sciences
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Christian M Loch
Fred Hutchinson Cancer Research Center
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Cynthia A Afshari
Amgen Inc.
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Akhilesh Pandey
Co-authored papers 1
Tsuyoshi Miyake
University of Virginia School of Medicine
Co-authored papers 1
Brian L Frey
University of Wisconsin-Madison, 1101 University Ave
Co-authored papers 1
Junbiao Dai
Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences
Co-authored papers 1
Florian Mueller
Institut Pasteur, Universite de Paris
Co-authored papers 1
Ralph S Baric
University of North Carolina
Co-authored papers 1
Jiang Qian
Co-authored papers 1
Friedrich F??rster
Utrecht University
Co-authored papers 1
Matthew B Frieman
Center for Pathogen Research, University of Maryland School of Medicine
Co-authored papers 1
Release 1.2