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Author Details

Joanne Lomas-Neira
Rhode Island Hospital and The Alpert School of Medicine at Brown University
2001
52
27
PMIDPaper TitleJournal TitlePublished Year
34907117Patho-Mechanisms for Hemorrhage/Sepsis-Induced Indirect Acute Respiratory Distress Syndrome: A Role for Lung TIE1 and Its Regulation by Neutrophils.Shock2022
30475329Hemorrhage Attenuates Neutrophil Recruitment in Response to Secondary Respiratory Infection by Pseudomonas Aeruginosa.Shock2019
29393983A novel role for coinhibitory receptors/checkpoint proteins in the immunopathology of sepsis.J Leukoc Biol2018
30134817Changes in the process of alternative RNA splicing results in soluble B and T lymphocyte attenuator with biological and clinical implications in critical illness.Mol Med2018
30619369Novel Role for PD-1:PD-L1 as Mediator of Pulmonary Vascular Endothelial Cell Functions in Pathogenesis of Indirect ARDS in Mice.Front Immunol2018
27864287Double-hit mouse model of cigarette smoke priming for acute lung injury.Am J Physiol Lung Cell Mol Physiol2017
28157452Activated β<sub>2</sub> Integrins Restrict Neutrophil Recruitment during Murine Acute Pseudomonal Pneumonia.Am J Respir Cell Mol Biol2017
27835962Soluble programmed cell death receptor-1 (sPD-1): a potential biomarker with anti-inflammatory properties in human and experimental acute respiratory distress syndrome (ARDS).J Transl Med2016
26529660BLOCKADE OF ENDOTHELIAL GROWTH FACTOR, ANGIOPOIETIN-2, REDUCES INDICES OF ARDS AND MORTALITY IN MICE RESULTING FROM THE DUAL-INSULTS OF HEMORRHAGIC SHOCK AND SEPSIS.Shock2016
24391146TAT-SNAP-23 treatment inhibits the priming of neutrophil functions contributing to shock and/or sepsis-induced extra-pulmonary acute lung injury.Innate Immun2015
26417200Biomarkers for Sepsis: What Is and What Might Be?Biomark Insights2015
25057927Programmed cell death receptor ligand 1 modulates the regulatory T cells' capacity to repress shock/sepsis-induced indirect acute lung injury by recruiting phosphatase SRC homology region 2 domain-containing phosphatase 1.Shock2015
23980650Neutrophil-endothelial interactions mediate angiopoietin-2-associated pulmonary endothelial cell dysfunction in indirect acute lung injury in mice.Am J Respir Cell Mol Biol2014
25082151Active players in resolution of shock/sepsis induced indirect lung injury: immunomodulatory effects of Tregs and PD-1.J Leukoc Biol2014
21997806Mechanisms of indirect acute lung injury: a novel role for the coinhibitory receptor, programmed death-1.Ann Surg2012
22983354Genetic disruption of protein kinase Cδ reduces endotoxin-induced lung injury.Am J Physiol Lung Cell Mol Physiol2012
23143057The acute immunological response to blood transfusion is influenced by polymicrobial sepsis.Shock2012
22552013The role and source of tumor necrosis factor-α in hemorrhage-induced priming for septic lung injury.Shock2012
22337009What's new in Shock, March 2012?Shock2012
21451443Local tissue expression of the cell death ligand, fas ligand, plays a central role in the development of extrapulmonary acute lung injury.Shock2011
21348592Pathogenesis of indirect (secondary) acute lung injury.Expert Rev Respir Med2011
20154604Therapeutic accessibility of caspase-mediated cell death as a key pathomechanism in indirect acute lung injury.Crit Care Med2010
19641139Lymphocytes in the development of lung inflammation: a role for regulatory CD4+ T cells in indirect pulmonary lung injury.J Immunol2009
18368145Epithelial cell apoptosis and neutrophil recruitment in acute lung injury-a unifying hypothesis? What we have learned from small interfering RNAs.Mol Med2008
19079669RNA interference as a potential therapeutic treatment for inflammation associated lung injury.Int J Clin Exp Med2008
18691096Apoptosis in sepsis: mechanisms, clinical impact and potential therapeutic targets.Curr Pharm Des2008
18369778Hydrodynamic delivery of siRNA in a mouse model of sepsis.Methods Mol Biol2008
17380787Blockade of apoptosis as a rational therapeutic strategy for the treatment of sepsis.Novartis Found Symp2007
17600273Fas-induced pulmonary apoptosis and inflammation during indirect acute lung injury.Am J Respir Crit Care Med2007
17665984Changes in dendritic cell function in the immune response to sepsis. Cell- &amp; tissue-based therapy.Expert Opin Biol Ther2007
17885380CXCL2 polymorphism in sepsis and acute respiratory distress syndrome: pathological significance lost in translation.Crit Care Med2007
16157517Role of alveolar macrophage and migrating neutrophils in hemorrhage-induced priming for ALI subsequent to septic challenge.Am J Physiol Lung Cell Mol Physiol2006
16793935Deficiency of gammadelta T lymphocytes contributes to mortality and immunosuppression in sepsis.Am J Physiol Regul Integr Comp Physiol2006
15695553In vivo gene silencing (with siRNA) of pulmonary expression of MIP-2 versus KC results in divergent effects on hemorrhage-induced, neutrophil-mediated septic acute lung injury.J Leukoc Biol2005
16182606Pepducins: an effective means to inhibit GPCR signaling by neutrophils.Trends Immunol2005
16303094The role and regulation of apoptosis in sepsis.J Endotoxin Res2005
16374370Shock and hemorrhage: an overview of animal models.Shock2005
16314469Silencing of Fas, but not caspase-8, in lung epithelial cells ameliorates pulmonary apoptosis, inflammation, and neutrophil influx after hemorrhagic shock and sepsis.Am J Pathol2005
15941915In vivo delivery of caspase-8 or Fas siRNA improves the survival of septic mice.Blood2005
15817707Leukocyte apoptosis and its significance in sepsis and shock.J Leukoc Biol2005
15961314Divergent roles of murine neutrophil chemokines in hemorrhage induced priming for acute lung injury.Cytokine2005
15123771CXCR2 inhibition suppresses hemorrhage-induced priming for acute lung injury in mice.J Leukoc Biol2004
15744129Sepsis-induced changes in macrophage co-stimulatory molecule expression: CD86 as a regulator of anti-inflammatory IL-10 response.Surg Infect (Larchmt)2004
12467642Pathological aspects of apoptosis in severe sepsis and shock?Int J Biochem Cell Biol2003
28443802Fas-Ligand Mediated Apoptosis in Severe Sepsis and Shock.Scand J Infect Dis2003
12949237Inhibition of Fas/Fas ligand signaling improves septic survival: differential effects on macrophage apoptotic and functional capacity.J Leukoc Biol2003
14620140Fas-ligand mediated apoptosis in severe sepsis and shock.Scand J Infect Dis2003
14572776Inhibition of CD1d activation suppresses septic mortality: a role for NK-T cells in septic immune dysfunction.J Surg Res2003
12688548Differential effects of macrophage inflammatory chemokine-2 and keratinocyte-derived chemokine on hemorrhage-induced neutrophil priming for lung inflammation: assessment by adoptive cells transfer in mice.Shock2003
12466142Shock-induced neutrophil mediated priming for acute lung injury in mice: divergent effects of TLR-4 and TLR-4/FasL deficiency.Am J Pathol2002
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Collaborators

Brown University
Co-authored papers 51
Nationwide Children's Hospital
Co-authored papers 4
Rhode Island Hospital and the Warren Alpert Medical School of Brown University
Co-authored papers 4
University of Florida
Co-authored papers 1
Boston Children's Hospital
Co-authored papers 1
University of Florida College of Medicine
Co-authored papers 1
University of Florida College of Medicine and Dentistry
Co-authored papers 1
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University of Occupational and Environmental Health
Co-authored papers 1
University of Florida, Univerzitet u Sarajevu Medicinski Fakultet
Co-authored papers 1
Memorial Sloan Kettering Cancer Center
Co-authored papers 1
23703Ocala Regional Medical Center
Co-authored papers 1
University of Michigan ann arbor
Co-authored papers 1
University of Florida Health
Co-authored papers 1
Molecular Cardiology Research Institute, Tufts Medical Center
Co-authored papers 1