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Author Details

Vanessa Tyrrell
Lowy Cancer Research Centre, Children's Cancer Institute
2014
20
7
PMIDPaper TitleJournal TitlePublished Year
36882456Histone H3-wild type diffuse midline gliomas with H3K27me3 loss are a distinct entity with exclusive EGFR or ACVR1 mutation and differential methylation of homeobox genes.Sci Rep2023
37726477Hopes, concerns, satisfaction and regret in a precision medicine trial for childhood cancer: a mixed-methods study of parent and patient perspectives.Br J Cancer2023
37013636A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer.Genome Med2023
36882456Histone H3-wild type diffuse midline gliomas with H3K27me3 loss are a distinct entity with exclusive EGFR or ACVR1 mutation and differential methylation of homeobox genes.Sci Rep2023
37382186Parents' expectations, preferences, and recall of germline findings in a childhood cancer precision medicine trial.Cancer2023
37253493Protocol for a comprehensive prospective cohort study of trio-based whole-genome sequencing for underlying cancer predisposition in paediatric and adolescent patients newly diagnosed with cancer: the PREDICT study.BMJ Open2023
37001527Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities.Cancer Cell2023
37523146High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer.Cancer Res2023
37511646Precision Medicine Is Changing the Roles of Healthcare Professionals, Scientists, and Research Staff: Learnings from a Childhood Cancer Precision Medicine Trial.J Pers Med2023
37523146High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer.Cancer Res2023
37511646Precision Medicine Is Changing the Roles of Healthcare Professionals, Scientists, and Research Staff: Learnings from a Childhood Cancer Precision Medicine Trial.J Pers Med2023
37726477Hopes, concerns, satisfaction and regret in a precision medicine trial for childhood cancer: a mixed-methods study of parent and patient perspectives.Br J Cancer2023
37253493Protocol for a comprehensive prospective cohort study of trio-based whole-genome sequencing for underlying cancer predisposition in paediatric and adolescent patients newly diagnosed with cancer: the PREDICT study.BMJ Open2023
37382186Parents' expectations, preferences, and recall of germline findings in a childhood cancer precision medicine trial.Cancer2023
37013636A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer.Genome Med2023
37001527Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities.Cancer Cell2023
34471258Whole-genome sequencing facilitates patient-specific quantitative PCR-based minimal residual disease monitoring in acute lymphoblastic leukaemia, neuroblastoma and Ewing sarcoma.Br J Cancer2022
35643837Returning raw genomic data: rights of research participants and obligations of health care professionals.Med J Aust2022
36066496The Voices of Stakeholders Involved in Precision Medicine: The Co-Design and Evaluation of Qualitative Indicators of Intervention Acceptability, Fidelity and Context in PRecISion Medicine for Children With Cancer in Australia.Qual Health Res2022
34471258Whole-genome sequencing facilitates patient-specific quantitative PCR-based minimal residual disease monitoring in acute lymphoblastic leukaemia, neuroblastoma and Ewing sarcoma.Br J Cancer2022
35643837Returning raw genomic data: rights of research participants and obligations of health care professionals.Med J Aust2022
36066496The Voices of Stakeholders Involved in Precision Medicine: The Co-Design and Evaluation of Qualitative Indicators of Intervention Acceptability, Fidelity and Context in PRecISion Medicine for Children With Cancer in Australia.Qual Health Res2022
33580196Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor.NPJ Precis Oncol2021
33580196Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor.NPJ Precis Oncol2021
32438909The rise of rapid implementation: a worked example of solving an existing problem with a new method by combining concept analysis with a systematic integrative review.BMC Health Serv Res2020
32075154"Balancing Expectations with Actual Realities": Conversations with Clinicians and Scientists in the First Year of a High-Risk Childhood Cancer Precision Medicine Trial.J Pers Med2020
31876116Optimization of a clofarabine-based drug combination regimen for the preclinical evaluation of pediatric acute lymphoblastic leukemia.Pediatr Blood Cancer2020
32438909The rise of rapid implementation: a worked example of solving an existing problem with a new method by combining concept analysis with a systematic integrative review.BMC Health Serv Res2020
32580982Development of an implementation and evaluation strategy for the Australian 'Zero Childhood Cancer' (Zero) Program: a study protocol.BMJ Open2020
31876116Optimization of a clofarabine-based drug combination regimen for the preclinical evaluation of pediatric acute lymphoblastic leukemia.Pediatr Blood Cancer2020
32075154"Balancing Expectations with Actual Realities": Conversations with Clinicians and Scientists in the First Year of a High-Risk Childhood Cancer Precision Medicine Trial.J Pers Med2020
32580982Development of an implementation and evaluation strategy for the Australian 'Zero Childhood Cancer' (Zero) Program: a study protocol.BMJ Open2020
31693904Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design.Cell Rep2019
31693904Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design.Cell Rep2019
30299205Integration of genomics, high throughput drug screening, and personalized xenograft models as a novel precision medicine paradigm for high risk pediatric cancer.Cancer Biol Ther2018
30220707Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma.Br J Cancer2018
30299205Integration of genomics, high throughput drug screening, and personalized xenograft models as a novel precision medicine paradigm for high risk pediatric cancer.Cancer Biol Ther2018
30220707Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma.Br J Cancer2018
27294016Quality standards for DNA sequence variation databases to improve clinical management under development in Australia.Appl Transl Genom2014
27294016Quality standards for DNA sequence variation databases to improve clinical management under development in Australia.Appl Transl Genom2014
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Collaborators

Children's Cancer Institute, Lowy Cancer Research Centre
Co-authored papers 12
Co-authored papers 11
School of Clinical Medicine
Co-authored papers 10
Children's Cancer Institute, Lowy Cancer Research Centre
Co-authored papers 9
Co-authored papers 8
Children's Cancer Institute, Lowy Cancer Research Centre
Co-authored papers 7
Co-authored papers 4
Co-authored papers 3
Hospital for Sick Children
Co-authored papers 3
Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine
Co-authored papers 3
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia
Co-authored papers 1
Children's Hospital of Philadelphia and the University of Pennsylvania
Co-authored papers 1
Xiangya Hospital of Central South University
Co-authored papers 1
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1
Collegeville
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
The University of Texas Health Science Center at San Antonio
Co-authored papers 1
Co-authored papers 1
Sun Yat-sen University Cancer Center
Co-authored papers 1
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Cancer Center, Texas Tech University Health Sciences Center School of Medicine
Co-authored papers 1
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Perelman School of Medicine at the University of Pennsylvania
Co-authored papers 1