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Author Details

Mohammad Minhajuddin
University of Colorado School of Medicine
2003
37
23
PMIDPaper TitleJournal TitlePublished Year
37358260A Novel Type of Monocytic Leukemia Stem Cell Revealed by the Clinical Use of Venetoclax-Based Therapy.Cancer Discov2023
37873284Targeting Acute Myeloid Leukemia Stem Cells Through Perturbation of Mitochondrial Calcium.bioRxiv2023
37051756Higher-dose venetoclax with measurable residual disease-guided azacitidine discontinuation in newly diagnosed acute myeloid leukemia.Haematologica2023
37110126Therapy-Resistant Acute Myeloid Leukemia Stem Cells Are Resensitized to Venetoclax + Azacitidine by Targeting Fatty Acid Desaturases 1 and 2.Metabolites2023
34525179The STAT3-MYC axis promotes survival of leukemia stem cells by regulating SLC1A5 and oxidative phosphorylation.Blood2022
35902048Outcomes Are Similar After Allogeneic Hematopoietic Stem Cell Transplant for Newly Diagnosed Acute Myeloid Leukemia Patients who Received Venetoclax + Azacitidine Versus Intensive Chemotherapy.Transplant Cell Ther2022
33028621The Hepatic Microenvironment Uniquely Protects Leukemia Cells through Induction of Growth and Survival Pathways Mediated by LIPG.Cancer Discov2021
34610123Venetoclax and azacitidine compared with induction chemotherapy for newly diagnosed patients with acute myeloid leukemia.Blood Adv2021
32334266Substituted oxindol-3-ylidenes as AMP-activated protein kinase (AMPK) inhibitors.Eur J Med Chem2020
31974170Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia.Cancer Discov2020
32822582Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells.Cell Stem Cell2020
30852438Low ferroportin expression in AML is correlated with good risk cytogenetics, improved outcomes and increased sensitivity to chemotherapy.Leuk Res2019
30943405The Hematopoietic Oxidase NOX2 Regulates Self-Renewal of Leukemic Stem Cells.Cell Rep2019
30420752Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia.Nat Med2018
29910151AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem Cells.Cell Stem Cell2018
30270124Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells.Cancer Cell2018
28280079Targeted therapy for a subset of acute myeloid leukemias that lack expression of aldehyde dehydrogenase 1A1.Haematologica2017
27374788Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche.Cell Stem Cell2016
27888238Rational design of a parthenolide-based drug regimen that selectively eradicates acute myelogenous leukemia stem cells.J Biol Chem2016
27573247Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells.J Biol Chem2016
24577530Flavaglines target primitive leukemia cells and enhance anti-leukemia drug activity.Leukemia2014
25057925Regulation of endothelial cell inflammation and lung polymorphonuclear lymphocyte infiltration by transglutaminase 2.Shock2014
23333149BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells.Cell Stem Cell2013
24089526Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells.J Biol Chem2013
24138944A phase I study of decitabine and rapamycin in relapsed/refractory AML.Leuk Res2013
23555849Critical role of non-muscle myosin light chain kinase in thrombin-induced endothelial cell inflammation and lung PMN infiltration.PLoS One2013
20889920Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways.Blood2010
19074768Protein kinase C-delta and phosphatidylinositol 3-kinase/Akt activate mammalian target of rapamycin to modulate NF-kappaB activation and intercellular adhesion molecule-1 (ICAM-1) expression in endothelial cells.J Biol Chem2009
19483084Essential role of cofilin-1 in regulating thrombin-induced RelA/p65 nuclear translocation and intercellular adhesion molecule 1 (ICAM-1) expression in endothelial cells.J Biol Chem2009
18362147Activation of Syk by protein kinase C-delta regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via tyrosine phosphorylation of RelA/p65.J Biol Chem2008
17158457Evidence for actin cytoskeleton-dependent and -independent pathways for RelA/p65 nuclear translocation in endothelial cells.J Biol Chem2007
17012367c-Src interacts with and phosphorylates RelA/p65 to promote thrombin-induced ICAM-1 expression in endothelial cells.Am J Physiol Lung Cell Mol Physiol2007
15778015Hypolipidemic and antioxidant properties of tocotrienol rich fraction isolated from rice bran oil in experimentally induced hyperlipidemic rats.Food Chem Toxicol2005
15843586Inhibition of mammalian target of rapamycin potentiates thrombin-induced intercellular adhesion molecule-1 expression by accelerating and stabilizing NF-kappa B activation in endothelial cells.J Immunol2005
15246972cAMP targeting of p38 MAP kinase inhibits thrombin-induced NF-kappaB activation and ICAM-1 expression in endothelial cells.Am J Physiol Lung Cell Mol Physiol2004
15548946Suppression of diethylnitrosamine and 2-acetylaminofluorene-induced hepatocarcinogenesis in rats by tocotrienol-rich fraction isolated from rice bran oil.Eur J Cancer Prev2004
14639121Suppression of 7,12-dimethylbenz[alpha]anthracene-induced carcinogenesis and hypercholesterolaemia in rats by tocotrienol-rich fraction isolated from rice bran oil.Eur J Cancer Prev2003
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Collaborators

Veronica Clavijo Jordan
Harvard Medical School
Co-authored papers 24
Shanshan Pei
Zhejiang University Medical Center
Co-authored papers 19
Brett M Stevens
University of Colorado School of Medicine
Co-authored papers 17
Daniel A Pollyea
University of Colorado Division of Hematology
Co-authored papers 16
Clayton A Smith
University of Colorado, Aurora CO.
Co-authored papers 11
Amanda Winters
University of Colorado School of Medicine
Co-authored papers 10
Angelo D'Alessandro
University of Colorado Anschutz Medical Campus
Co-authored papers 9
Maria Amaya
University of Colorado School of Medicine
Co-authored papers 8
Haobin Ye
Institute of Metabolism & Integrative Biology, Fudan University
Co-authored papers 8
Biniam Adane
The Broad Institute of MIT and Harvard
Co-authored papers 7
Courtney L Jones
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 7
Michael W Becker
James P. Wilmot Cancer Institute, University of Rochester Medical Center Rochester
Co-authored papers 7
Diana Abbott
Center for Innovative Design and Analysis, University of Colorado, Aurora CO.
Co-authored papers 6
Anagha Inguva
University of Colorado School of Medicine
Co-authored papers 6
Maura Gasparetto
University of Colorado School of Medicine
Co-authored papers 5
Travis Nemkov
University of Colorado Anschutz Medical Campus
Co-authored papers 4
Anna Krug
University of Colorado School of Medicine
Co-authored papers 4
Rachel Culp-Hill
University of Colorado Anschutz Medical Campus
Co-authored papers 4
Kirk C Hansen
University of Colorado Anschutz Medical Campus
Co-authored papers 2
Subhajyoti De
Co-authored papers 2
Fabia Gamboni
University of Colorado Anschutz Medical Campus
Co-authored papers 2
Julie A Reisz
University of Colorado Anschutz Medical Campus
Co-authored papers 2
Christopher Y Park
NYU Robert I. Grossman School of Medicine
Co-authored papers 1
Jeremy N Rich
UPMC Hillman Cancer Center, University of Pittsburgh Medical Center
Co-authored papers 1
Sarah Gehrke
University of Colorado Anschutz Medical Campus
Co-authored papers 1
Aik Choon Tan
Huntsman Cancer Institute, The University of Utah
Co-authored papers 1
Tonya Brunetti
Co-authored papers 1
Annika Gustafson
University of Colorado Denver
Co-authored papers 1
Stephen C Mack
St Jude Children's Research Hospital
Co-authored papers 1
Sweta B Patel
The University of Alabama at Birmingham School of Medicine
Co-authored papers 1
Release 1.2