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Author Details
Full Name
Yungui Zhou
Affiliation
Gladstone Institutes
ORCID
Career Start Year
2001
Papers
30
H Index
25
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
35063084
Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.
Cell
2022
35413950
Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy.
Nat Commun
2022
34426831
BMP receptor blockade overcomes extrinsic inhibition of remyelination and restores neurovascular homeostasis.
Brain
2021
34851693
AD-linked R47H-<i>TREM2</i> mutation induces disease-enhancing microglial states via AKT hyperactivation.
Sci Transl Med
2021
32792571
Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia.
Sci Rep
2020
31873194
Microglial microRNAs mediate sex-specific responses to tau pathology.
Nat Neurosci
2020
33054973
A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain.
Elife
2020
30735499
Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain.
PLoS Biol
2019
31206174
Decreased A20 expression on circulating CD56<sup>bright</sup> NK cells contributes to a worse disease status in patients with ankylosing spondylitis.
Clin Exp Immunol
2019
30232263
Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy.
Proc Natl Acad Sci U S A
2018
29124108
An 8-week, open-label, dose-finding study of nimodipine for the treatment of progranulin insufficiency from <i>GRN</i> gene mutations.
Alzheimers Dement (N Y)
2017
27041503
Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss.
Neuron
2016
27356871
Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment.
Mol Neurodegener
2016
25589773
SIRT1 deficiency in microglia contributes to cognitive decline in aging and neurodegeneration via epigenetic regulation of IL-1β.
J Neurosci
2015
26390242
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.
Nat Med
2015
25261995
Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.
Nat Med
2014
22272874
Selective targeting of microglia by quantum dots.
J Neuroinflammation
2012
23024364
Cathepsin B degrades amyloid-β in mice expressing wild-type human amyloid precursor protein.
J Biol Chem
2012
21771791
CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease.
J Biol Chem
2011
20869593
Acetylation of tau inhibits its degradation and contributes to tauopathy.
Neuron
2010
19951690
Imbalance between GABAergic and Glutamatergic Transmission Impairs Adult Neurogenesis in an Animal Model of Alzheimer's Disease.
Cell Stem Cell
2009
18957217
Cystatin C-cathepsin B axis regulates amyloid beta levels and associated neuronal deficits in an animal model of Alzheimer's disease.
Neuron
2008
18931664
Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease.
Nat Neurosci
2008
16982417
Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease.
Neuron
2006
15699179
Targeted disruption of the Artemis murine counterpart results in SCID and defective V(D)J recombination that is partially corrected with bone marrow transplantation.
J Immunol
2005
16183991
SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling.
J Biol Chem
2005
12055248
A founder mutation in Artemis, an SNM1-like protein, causes SCID in Athabascan-speaking Native Americans.
J Immunol
2002
12224067
Prenatal diagnosis and carrier detection for Athabascan severe combined immunodeficiency disease.
Prenat Diagn
2002
12444116
Multilineage engraftment with minimal graft-versus-host disease following in utero transplantation of S-59 psoralen/ultraviolet a light-treated, sensitized T cells and adult T cell-depleted bone marrow in fetal mice.
J Immunol
2002
11740386
Increased engraftment and GVHD after in utero transplantation of MHC-mismatched bone marrow cells and CD80low, CD86(-) dendritic cells in a fetal mouse model.
Transplantation
2001
1 - 30 of 30
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