Author details

Full Name

Sarah Franklin

Affiliation

ORCID

Career Start Year

2010

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36980931	Identification of Two Homozygous Variants in and Genes Associated with Severe Infantile Cardiomyopathy.		2023
36448446	Distinct Transcriptomic and Proteomic Profile Specifies Patients Who Have Heart Failure With Potential of Myocardial Recovery on Mechanical Unloading and Circulatory Support.	Circulation	2023
37212935	SMYD1a protects the heart from ischemic injury by regulating OPA1-mediated cristae remodeling and supercomplex formation.		2023
36816640	Correction to "Histone H4K20 Trimethylation Is Decreased in Murine Models of Heart Disease".		2023
35725853	Author Correction: Mitochondrial calcium uniporter stabilization preserves energetic homeostasis during Complex I impairment.	Nat Commun	2022
35589699	Mitochondrial calcium uniporter stabilization preserves energetic homeostasis during Complex I impairment.	Nat Commun	2022
34081951	The role of demethylases in cardiac development and disease.	Journal of Molecular and Cellular Cardiology	2021
33953175	The lncRNA Caren antagonizes heart failure by inactivating DNA damage response and activating mitochondrial biogenesis.	Nature Communications	2021
32822544	Transcriptional regulation by methyltransferases and their role in the heart: highlighting novel emerging functionality.	American Journal of Physiology - Heart and Circulatory Physiology	2020
31253771	Structural and functional analysis of the role of the chaperonin CCT in mTOR complex assembly.	Nature Communications	2019
31597091	Identification of a Paracrine Signaling Mechanism Linking CD34 Progenitors to the Regulation of Visceral Fat Expansion and Remodeling.	Cell Reports	2019
31530639	Molecular architecture of the Bardet-Biedl syndrome protein 2-7-9 subcomplex.	Journal of Biological Chemistry	2019
29435515	The Smyd Family of Methyltransferases: Role in Cardiac and Skeletal Muscle Physiology and Pathology.	Current Opinion in Physiology	2018
30061404	Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart.	Proc Natl Acad Sci U S A	2018
28801480	GFI1 functions in transcriptional control and cell fate determination require SNAG domain methylation to recruit LSD1.	Biochemical Journal	2017
27663768	The chromatin-binding protein Smyd1 restricts adult mammalian heart growth.	American Journal of Physiology - Heart and Circulatory Physiology	2016
27226577	Reciprocal Regulation of the Cardiac Epigenome by Chromatin Structural Proteins Hmgb and Ctcf: IMPLICATIONS FOR TRANSCRIPTIONAL REGULATION.	J Biol Chem	2016
27480105	GFI1 functions in transcriptional control and cell fate determination require SNAG domain methylation to recruit LSD1.	Biochem J	2016
25675501	Structures of the GÎ²-CCT and PhLP1-GÎ²-CCT complexes reveal a mechanism for G-protein Î²-subunit folding and GÎ²Î³ dimer assembly.	Proceedings of the National Academy of Sciences of the United States of America	2015
25588501	Mitochondrial Ca(2+) uptake by the voltage-dependent anion channel 2 regulates cardiac rhythmicity.	Elife	2015
25790351	Metabolic remodeling in moderate synchronous versus dyssynchronous pacing-induced heart failure: integrated metabolomics and proteomics study.	PLoS ONE	2015
24876127	Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex.	Elife	2014
24675841	TBX3 regulates splicing in vivo: a novel molecular mechanism for Ulnar-mammary syndrome.	PLoS Genet	2014
23606250	Systems proteomics of healthy and diseased chromatin.	Methods in Molecular Biology	2013
24077883	Systems proteomics of cardiac chromatin identifies nucleolin as a regulator of growth and cellular plasticity in cardiomyocytes.	Am J Physiol Heart Circ Physiol	2013
24327956	PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response.	Mol Metab	2013
22266334	Investigation into the role of phosphatidylserine in modifying the susceptibility of human lymphocytes to secretory phospholipase A(2) using cells deficient in the expression of scramblase.		2012
22846883	Features of endogenous cardiomyocyte chromatin revealed by super-resolution STED microscopy.	Journal of Molecular and Cellular Cardiology	2012
22270000	Quantitative analysis of the chromatin proteome in disease reveals remodeling principles and identifies high mobility group protein B2 as a regulator of hypertrophic growth.	Molecular and Cellular Proteomics	2012
22940112	Structural considerations for chromatin state models with transcription as a functional readout.	FEBS Letters	2012
23299252	Quantitative analysis of chromatin proteomes in disease.	Journal of Visualized Experiments	2012
22010165	Genomes, proteomes, and the central dogma.	Circulation: Cardiovascular Genetics	2011
20807835	Specialized compartments of cardiac nuclei exhibit distinct proteomic anatomy.	Mol Cell Proteomics	2011
21080425	Highly efficient purification of protein complexes from mammalian cells using a novel streptavidin-binding peptide and hexahistidine tandem tag system: application to Bruton's tyrosine kinase.	Protein Science	2011
21471215	Metal-driven operation of the human large-conductance voltage- and Ca2+-dependent potassium channel (BK) gating ring apparatus.	Journal of Biological Chemistry	2011
20543088	Stress signaling by Tec tyrosine kinase in the ischemic myocardium.	Am J Physiol Heart Circ Physiol	2010
20170660	Post-translational regulation of calsarcin-1 during pressure overload-induced cardiac hypertrophy.	Journal of Molecular and Cellular Cardiology	2010