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Author Details

Andrei A Korostelev
RNA Therapeutics Institute, University of Massachusetts Chan Medical School
2002
57
30
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35287473The Structural Dynamics of Translation.Annu Rev Biochem2022
35589706Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.Nat Commun2022
36182693Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.Mol Cell2022
34330903Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation.Nat Commun2021
34903725Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP.Nat Commun2021
34565314Diversity and Similarity of Termination and Ribosome Rescue in Bacterial, Mitochondrial, and Cytoplasmic Translation.Biochemistry (Mosc)2021
32427100mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding.Elife2020
33144582ArfB can displace mRNA to rescue stalled ribosomes.Nat Commun2020
32606306Structural characterization of a novel human adeno-associated virus capsid with neurotropic properties.Nat Commun2020
32817446Termi-Luc: a versatile assay to monitor full-protein release from ribosomes.RNA2020
32612237Cryo-EM of elongating ribosome with EF-Tuâ¿¢GTP elucidates tRNA proofreading.Nature2020
32518240Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly.Nat Commun2020
30735661The Genetic Landscape of Diamond-Blackfan Anemia.Am J Hum Genet2019
31513010Extensive ribosome and RF2 rearrangements during translation termination.Elife2019
29247757Structural dynamics of protein S1 on the 70S ribosome visualized by ensemble cryo-EM.Methods2018
29941456Mechanism of premature translation termination on a sense codon.J Biol Chem2018
30503522The Genetic Landscape of Diamond-Blackfan Anemia.Am J Hum Genet2018
29731232Conformational Control of Translation Termination on the 70S Ribosome.Structure2018
29366636Mechanism of Inhibition of Translation Termination by Blasticidin S.J Mol Biol2018
28538735Ensemble cryo-EM elucidates the mechanism of translation fidelity.Nature2017
28300532Mechanism of ribosome rescue by ArfA and RF2.Elife2017
28428565Small methyltransferase RlmH assembles a composite active site to methylate a ribosomal pseudouridine.Sci Rep2017
29027901Structure of RNA polymerase bound to ribosomal 30S subunit.Elife2017
27107638Structural Basis for Translation Termination on a Pseudouridylated Stop Codon.J Mol Biol2016
26673695MMB-GUI: a fast morphing method demonstrates a possible ribosomal tRNA translocation trajectory.Nucleic Acids Res2016
27159452Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.Elife2016
27434674Ribosomeâ¿¢RelA structures reveal the mechanism of stringent response activation.Elife2016
25652826Initiation of translation in bacteria by a structured eukaryotic IRES RNA.Nature2015
26412335Ribosome Structure Reveals Preservation of Active Sites in the Presence of a P-Site Wobble Mismatch.Structure2015
24927574Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.Proc Natl Acad Sci U S A2014
25417100A deeper look into translation initiation.Cell2014
25043550Structures of yeast 80S ribosome-tRNA complexes in the rotated and nonrotated conformations.Structure2014
23769667Crystal structure of the 70S ribosome bound with the Q253P mutant form of release factor RF2.Structure2013
24324137Structure of the ribosome with elongation factor G trapped in the pretranslocation state.Proc Natl Acad Sci U S A2013
23824292Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome.Proc Natl Acad Sci U S A2013
22999888Crystal structures of 70S ribosomes bound to release factors RF1, RF2 and RF3.Curr Opin Struct Biol2012
21245352Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome.Proc Natl Acad Sci U S A2011
21729334Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1.BMC Biol2011
21729333Structural and functional basis for RNA cleavage by Ire1.BMC Biol2011
21700725Structural aspects of translation termination on the ribosome.RNA2011
20588254Recognition of the amber UAG stop codon by release factor RF1.EMBO J2010
19079236The unfolded protein response signals through high-order assembly of Ire1.Nature2009
19822758Multistart simulated annealing refinement of the crystal structure of the 70S ribosome.Proc Natl Acad Sci U S A2009
18596689Structural basis for translation termination on the 70S ribosome.Nature2008
19064930Crystal structure of a translation termination complex formed with release factor RF2.Proc Natl Acad Sci U S A2008
18848900Structural dynamics of the ribosome.Curr Opin Chem Biol2008
17764954The ribosome in focus: new structures bring new insights.Trends Biochem Sci2007
17940016Interactions and dynamics of the Shine Dalgarno helix in the 70S ribosome.Proc Natl Acad Sci U S A2007
17897673Analysis of structural dynamics in the ribosome by TLS crystallographic refinement.J Mol Biol2007
16510969Bias in cross-validated free R factors: mitigation of the effects of non-crystallographic symmetry.Acta Crystallogr D Biol Crystallogr2006
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Collaborators

RNA Therapeutics Institute, University of Massachusetts Chan Medical School
Co-authored papers 9
University of Missouri
Co-authored papers 6
University of California san francisco
Co-authored papers 4
University of California San Francisco
Co-authored papers 3
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Co-authored papers 3
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Co-authored papers 3
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Co-authored papers 3
Boston Children's Hospital
Co-authored papers 2
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Broad Institute of MIT and Harvard
Co-authored papers 2
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Co-authored papers 2
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Vanderbilt-Ingram Cancer Center, Vanderbilt University
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Howard Hughes Medical Institute
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Broad Institute of MIT and Harvard
Co-authored papers 2
Co-authored papers 2
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Co-authored papers 2
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University of California San Francisco
Co-authored papers 1
School of Public Health, University at Albany
Co-authored papers 1
Columbia University
Co-authored papers 1