|
| 36599987 | Structural basis of broad-spectrum β-lactam resistance in Staphylococcus aureus. | Nature | 2023 |
| 37713458 | Structural Insights into Type III Secretion Systems of the Bacterial Flagellum and Injectisome. | Annu Rev Microbiol | 2023 |
| 37555275 | A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. | Emerg Microbes Infect | 2023 |
| 37493438 | Identification of an Optimized Receptor-Binding Domain Subunit Vaccine against SARS-CoV-2. | J Immunol | 2023 |
| 37235809 | Investigation into the Mechanism of Action of the Tuberculosis Drug Candidate SQ109 and Its Metabolites and Analogues in Mycobacteria. | J Med Chem | 2023 |
| 36914633 | An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicity. | Nat Commun | 2023 |
| 36930801 | Large-Scale Virtual Screening for the Discovery of SARS-CoV-2 Papain-like Protease (PLpro) Non-covalent Inhibitors. | J Chem Inf Model | 2023 |
| 36940280 | Vinyl Halide-Modified Unsaturated Cyclitols are Mechanism-Based Glycosidase Inhibitors. | Angew Chem Int Ed Engl | 2023 |
| 34792586 | Crystal structure of the Propionibacterium acnes surface sialidase, a drug target for P. acnes-associated diseases. | Glycobiology | 2022 |
| 35347989 | The Impact of Second Coordination Sphere Methionine-Aromatic Interactions in Copper Proteins. | Inorg Chem | 2022 |
| 35654690 | Recent structural advances towards understanding of the bacterial type III secretion injectisome. | Trends Biochem Sci | 2022 |
| 36057636 | X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation. | Nat Commun | 2022 |
| 35019716 | The Hinge Region of the Israeli Acute Paralysis Virus Internal Ribosome Entry Site Directs Ribosomal Positioning, Translational Activity, and Virus Infection. | J Virol | 2022 |
| 32877645 | Characterization of the Pilotin-Secretin Complex from the Salmonella enterica Type III Secretion System Using Hybrid Structural Methods. | Structure | 2021 |
| 33819634 | Crystallographic analysis of TarI and TarJ, a cytidylyltransferase and reductase pair for CDP-ribitol synthesis in Staphylococcus aureus wall teichoic acid biogenesis. | J Struct Biol | 2021 |
| 33723038 | Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1. | Proc Natl Acad Sci U S A | 2021 |
| 35024120 | Automated discovery of noncovalent inhibitors of SARS-CoV-2 main protease by consensus Deep Docking of 40 billion small molecules. | Chem Sci | 2021 |
| 34473495 | Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria. | J Med Chem | 2021 |
| 33986273 | CryoEM structure of the antibacterial target PBP1b at 3.3⿿ÿ resolution. | Nat Commun | 2021 |
| 34151961 | PBP4-mediated β-lactam resistance among clinical strains of Staphylococcus aureus. | J Antimicrob Chemother | 2021 |
| 33139287 | Structural and Cellular Insights into the l,d-Transpeptidase YcbB as a Therapeutic Target in Citrobacter rodentium, <i>Salmonella</i> Typhimurium, and <i>Salmonella</i> Typhi Infections. | Antimicrob Agents Chemother | 2021 |
| 33453150 | Cryo-EM structure of the EspA filament from enteropathogenic Escherichia coli: Revealing the mechanism of effector translocation in the T3SS. | Structure | 2021 |
| 33412091 | The active DNA-PK holoenzyme occupies a tensed state in a staggered synaptic complex. | Structure | 2021 |
| 32293878 | Aligning the Symmetry of the Type III Secretion System Needle Complex. | J Chem Inf Model | 2020 |
| 31969390 | Crystallographic analysis of <i>Staphylococcus aureus</i> LcpA, the primary wall teichoic acid ligase. | J Biol Chem | 2020 |
| 31821956 | Towards capture of dynamic assembly and action of the T3SS at near atomic resolution. | Curr Opin Struct Biol | 2020 |
| 33144379 | SPOR Proteins Are Required for Functionality of Class A Penicillin-Binding Proteins in Escherichia coli. | mBio | 2020 |
| 33129970 | Cryo-EM analysis of the SctV cytosolic domain from the enteropathogenic E. coli T3SS injectisome. | J Struct Biol | 2020 |
| 33208735 | Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site. | Nat Commun | 2020 |
| 32998902 | Structural insight into the Staphylococcus aureus ATP-driven exporter of virulent peptide toxins. | Sci Adv | 2020 |
| 32518158 | Structural analysis of avibactam-mediated activation of the bla and mec divergons in methicillin-resistant <i>Staphylococcus aureus</i>. | J Biol Chem | 2020 |
| 32234311 | A Slippery Scaffold: Synthesis and Recycling of the Bacterial Cell Wall Carrier Lipid. | J Mol Biol | 2020 |
| 32320673 | Structure of the Peptidoglycan Synthase Activator LpoP in Pseudomonas aeruginosa. | Structure | 2020 |
| 30681070 | A Hybrid Secretion System Facilitates Bacterial Sporulation: A Structural Perspective. | Microbiol Spectr | 2019 |
| 31427728 | T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly. | Nat Microbiol | 2019 |
| 31534650 | On the road to structure-based development of anti-virulence therapeutics targeting the type III secretion system injectisome. | Medchemcomm | 2019 |
| 30713527 | Recognition of Peptidoglycan Fragments by the Transpeptidase PBP4 From <i>Staphylococcus aureus</i>. | Front Microbiol | 2019 |
| 31015395 | Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli. | Nat Commun | 2019 |
| 30733444 | Cryo-EM structure of the homohexameric T3SS ATPase-central stalk complex reveals rotary ATPase-like asymmetry. | Nat Commun | 2019 |
| 31056420 | Structural Insights into Bacteriophage GIL01 gp7 Inhibition of Host LexA Repressor. | Structure | 2019 |
| 29288127 | Structural characterization of SpoIIIAB sporulation-essential protein in Bacillus subtilis. | J Struct Biol | 2018 |
| 30242280 | Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin. | Nat Commun | 2018 |
| 29886194 | Structural and biochemical characterization of SpoIIIAF, a component of a sporulation-essential channel in Bacillus subtilis. | J Struct Biol | 2018 |
| 29885610 | Enzyme structures of the bacterial peptidoglycan and wall teichoic acid biogenesis pathways. | Curr Opin Struct Biol | 2018 |
| 30122450 | Insights into Heptosyltransferase I Catalysis and Inhibition through the Structure of Its Ternary Complex. | Structure | 2018 |
| 30095200 | Characterization of the two conformations adopted by the T3SS inner-membrane protein PrgK. | Protein Sci | 2018 |
| 30015474 | Structural Basis for Binding of Fluorescent CMP-Neu5Ac Mimetics to Enzymes of the Human ST8Sia Family. | ACS Chem Biol | 2018 |
| 30366985 | Structural and kinetic analyses of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance in <i>Staphylococcus aureus</i>. | J Biol Chem | 2018 |
| 29581275 | IpdAB, a virulence factor in <i>Mycobacterium tuberculosis</i>, is a cholesterol ring-cleaving hydrolase. | Proc Natl Acad Sci U S A | 2018 |
| 29360990 | PBP4 activity and its overexpression are necessary for PBP4-mediated high-level β-lactam resistance. | J Antimicrob Chemother | 2018 |