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Author Details

Casey M Theriot
College of Veterinary Medicine, North Carolina State University
2009
60
27
PMIDPaper TitleJournal TitlePublished Year
38018975Loss of <i>Bacteroides thetaiotaomicron</i> bile acid-altering enzymes impacts bacterial fitness and the global metabolic transcriptome.Microbiol Spectr2024
36914755Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut.Nat Microbiol2023
37796494Using Multidimensional Separations to Distinguish Isomeric Amino Acid-Bile Acid Conjugates and Assess Their Presence and Perturbations in Model Systems.Anal Chem2023
37695856The microbial-derived bile acid lithocholate and its epimers inhibit <i>Clostridioides difficile</i> growth and pathogenicity while sparing members of the gut microbiota.J Bacteriol2023
37425690Loss of <i>Bacteroides thetaiotaomicron</i> bile acid altering enzymes impact bacterial fitness and the global metabolic transcriptome.bioRxiv2023
37333390The microbial derived bile acid lithocholate and its epimers inhibit <i>Clostridioides difficile</i> growth and pathogenicity while sparing members of the gut microbiota.bioRxiv2023
37126691Intestinal bile acids provide a surmountable barrier against <i>C. difficile</i> TcdB-induced disease pathogenesis.Proc Natl Acad Sci U S A2023
35012435Prolonged oral antimicrobial administration prevents doxorubicin-induced loss of active intestinal stem cells.Gut Microbes2022
38046906Probiotic colonization dynamics after oral consumption of VSL#3<sup>®</sup> by antibiotic-treated mice.Microbiome Res Rep2022
35350846The Stickland Reaction Precursor <i>trans</i>-4-Hydroxy-l-Proline Differentially Impacts the Metabolism of Clostridioides difficile and Commensal <i>Clostridia</i>.mSphere2022
35862710Tauroursodeoxycholic Acid Inhibits Clostridioides difficile Toxin-Induced Apoptosis.Infect Immun2022
36274154Bile acid distributions, sex-specificity, and prognosis in colorectal cancer.Biol Sex Differ2022
33469019Clostridioides difficile exploits toxin-mediated inflammation to alter the host nutritional landscape and exclude competitors from the gut microbiota.Nat Commun2021
33600468Secondary bile acid ursodeoxycholic acid alters weight, the gut microbiota, and the bile acid pool in conventional mice.PLoS One2021
33673352Contribution of Inhibitory Metabolites and Competition for Nutrients to Colonization Resistance against <i>Clostridioides difficile</i> by Commensal <i>Clostridium</i>.Microorganisms2021
33526676<i>Lactobacillus</i> bile salt hydrolase substrate specificity governs bacterial fitness and host colonization.Proc Natl Acad Sci U S A2021
33326565Mechanisms of Colonization Resistance Against Clostridioides difficile.J Infect Dis2021
31595814Diversification of host bile acids by members of the gut microbiota.Gut Microbes2020
33093042Complete Genome Sequence of Lactobacillus johnsonii NCK2677, Isolated from Mice.Microbiol Resour Announc2020
32589955Role of Microbiota-Derived Bile Acids in Enteric Infections.Cell2020
33022384Clostridioides difficile carriage in animals and the associated changes in the host fecal microbiota.Anaerobe2020
32179626Strain-Dependent Inhibition of Clostridioides difficile by Commensal <i>Clostridia</i> Carrying the Bile Acid-Inducible (<i>bai</i>) Operon.J Bacteriol2020
32205405Ursodeoxycholic Acid (UDCA) Mitigates the Host Inflammatory Response during Clostridioides difficile Infection by Altering Gut Bile Acids.Infect Immun2020
32482070Salicylanilide Analog Minimizes Relapse of <i>Clostridioides difficile</i> Infection in Mice.J Med Chem2020
32156803<i>In Vivo</i> Targeting of Clostridioides difficile Using Phage-Delivered CRISPR-Cas3 Antimicrobials.mBio2020
30845232Bile salt hydrolases: Gatekeepers of bile acid metabolism and host-microbiome crosstalk in the gastrointestinal tract.PLoS Pathog2019
31584976Ceftiofur formulation differentially affects the intestinal drug concentration, resistance of fecal Escherichia coli, and the microbiome of steers.PLoS One2019
31269198High-throughput amplicon sequencing of the full-length 16S rRNA gene with single-nucleotide resolution.Nucleic Acids Res2019
31403467Human fecal metabolomic profiling could inform Clostridioides difficile infection diagnosis and treatment.J Clin Invest2019
29556548Beyond Structure: Defining the Function of the Gut Using Omic Approaches for Rational Design of Personalized Therapeutics.mSystems2018
29928268A Small Molecule-Screening Pipeline to Evaluate the Therapeutic Potential of 2-Aminoimidazole Molecules Against <i>Clostridium difficile</i>.Front Microbiol2018
29848760The <i>Lactobacillus</i> Bile Salt Hydrolase Repertoire Reveals Niche-Specific Adaptation.mSphere2018
30283418Dosing Regimen of Enrofloxacin Impacts Intestinal Pharmacokinetics and the Fecal Microbiota in Steers.Front Microbiol2018
29600278Shifts in the Gut Metabolome and <i>Clostridium difficile</i> Transcriptome throughout Colonization and Infection in a Mouse Model.mSphere2018
29654837Restoration of short chain fatty acid and bile acid metabolism following fecal microbiota transplantation in patients with recurrent Clostridium difficile infection.Anaerobe2018
29798856Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells.Science2018
28478276Introduction to the special issue highlighting Anaerobe 2016.Anaerobe2017
28279860Inhibition of spore germination, growth, and toxin activity of clinically relevant C. difficile strains by gut microbiota derived secondary bile acids.Anaerobe2017
27163871Impact of microbial derived secondary bile acids on colonization resistance against Clostridium difficile in the gastrointestinal tract.Anaerobe2016
28060346Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291.J Vis Exp2016
27239563Metabolic Model-Based Integration of Microbiome Taxonomic and Metabolomic Profiles Elucidates Mechanistic Links between Ecological and Metabolic Variation.mSystems2016
27239562Antibiotic-Induced Alterations of the Gut Microbiota Alter Secondary Bile Acid Production and Allow for Clostridium difficile Spore Germination and Outgrowth in the Large Intestine.mSphere2016
25327211Interleukin-22 and CD160 play additive roles in the host mucosal response to Clostridium difficile infection in mice.Immunology2015
26488281Interactions Between the Gastrointestinal Microbiome and Clostridium difficile.Annu Rev Microbiol2015
26169276Fecal Microbiota Transplantation Eliminates Clostridium difficile in a Murine Model of Relapsing Disease.Infect Immun2015
25547352Effects of tigecycline and vancomycin administration on established Clostridium difficile infection.Antimicrob Agents Chemother2015
25534943Dynamics and establishment of Clostridium difficile infection in the murine gastrointestinal tract.Infect Immun2015
24445449Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection.Nat Commun2014
25230329Clostridium difficile-induced colitis in mice is independent of leukotrienes.Anaerobe2014
24590475Alteration of the murine gastrointestinal microbiota by tigecycline leads to increased susceptibility to Clostridium difficile infection.Antimicrob Agents Chemother2014
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Collaborators

Vincent B Young
University of Michigan ann arbor
Co-authored papers 15
Rodolphe Barrangou
Innovative Genomics Institute, University of California berkeley
Co-authored papers 8
Ingrid L Bergin
University of Michigan ann arbor
Co-authored papers 6
Stephanie A Montgomery
and Lineberger Comprehensive Cancer Center, University of North Carolina System
Co-authored papers 4
Pieter C Dorrestein
Co-authored papers 2
David M Aronoff
Indiana University School of Medicine
Co-authored papers 2
Patrick D Schloss
University of Michigan ann arbor
Co-authored papers 2
Sarah K McGill
University of North Carolina School of Medicine
Co-authored papers 2
Tim F Greten
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
Qiong Fu
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
Jay A Berzofsky
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
Bernd Heinrich
Clinic for Gastroenterology, Hannover Medical School
Co-authored papers 1
Shurjo K Sen
Louisiana State University
Co-authored papers 1
Mathuros Ruchirawat
Chulabhorn Research Institute
Co-authored papers 1
John A McCulloch
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
Matthew R Redinbo
University of North Carolina at Chapel Hill
Co-authored papers 1
Sujatha Srinivasan
Fred Hutchinson Cancer Center
Co-authored papers 1
Milan Sandhu
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
Firouzeh Korangy
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
Masaki Terabe
National Cancer Institute
Co-authored papers 1
Thomas Longerich
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 1
Thomas Ritz
Southern Methodist University
Co-authored papers 1
Giorgio Trinchieri
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
Soumen Roy
Center for Cancer Research
Co-authored papers 1
Victor J DiRita
Michigan State University
Co-authored papers 1
Bo Li
The University of North Carolina at Chapel Hill
Co-authored papers 1
Valerie Fako
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
Miaojun Han
Department of Research and Development, Shanghai United Imaging Intelligence Co.
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Chi Ma
Affiliated Yantai Yuhuangding Hospital of Qingdao University
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Release 1.2