Author details

Full Name

Kevin H Gardner

Affiliation

CUNY Advanced Science Research Center

ORCID

Career Start Year

1971

Papers

118

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
37961463	Identification of Small Molecule Ligand Binding Sites On and In the ARNT PAS-B Domain.	bioRxiv	2024
37331599	Diversity of function and higher-order structure within HWE sensor histidine kinases.	J Biol Chem	2023
37732199	Signal-regulated unmasking of the nuclear localization motif in the PAS domain regulates the nuclear translocation of PASK.	bioRxiv	2023
34978789	Designing Single-Component Optogenetic Membrane Recruitment Systems: The Rho-Family GTPase Signaling Toolbox.	ACS Synth Biol	2022
34478635	Two steps, one ligand: How PPARÎ³ binds small-molecule agonists.	Structure	2021
35603043	Fragile protein folds: Sequence and environmental factors affecting the equilibrium of two interconverting, stably folded protein conformations.	Magn Reson (Gott)	2021
33781746	Lighting the way: Recent insights into the structure and regulation of phototropin blue light receptors.	J Biol Chem	2021
33555975	TAEL 2.0: An Improved Optogenetic Expression System for Zebrafish.	Zebrafish	2021
33524371	Volume and compressibility differences between protein conformations revealed by high-pressure NMR.	Biophys J	2021
32880430	Unraveling the Mechanism of a LOV Domain Optogenetic Sensor: A Glutamine Lever Induces Unfolding of the JÎ± Helix.	ACS Chem Biol	2020
30611431	Isotopic Labeling of Eukaryotic Membrane Proteins for NMR Studies of Interactions and Dynamics.	Methods Enzymol	2019
30808807	Insights into histidine kinase activation mechanisms from the monomeric blue light sensor EL346.	Proc Natl Acad Sci U S A	2019
31120626	Shining light on the alphaproteobacterial general stress response: Comment on: Fiebig et al., Mol Microbiol, 2019.	Mol Microbiol	2019
29984995	Blue-Light Receptors for Optogenetics.	Chem Rev	2018
30121871	On the use of Pichia pastoris for isotopic labeling of human GPCRs for NMR studies.	J Biomol NMR	2018
30065115	Directly light-regulated binding of RGS-LOV photoreceptors to anionic membrane phospholipids.	Proc Natl Acad Sci U S A	2018
27993986	TAEL: a zebrafish-optimized optogenetic gene expression system with fine spatial and temporal control.	Development	2017
28984574	Ligand modulation of sidechain dynamics in a wild-type human GPCR.	Elife	2017
26894386	Erratum to: Methyl labeling and TROSY NMR spectroscopy of proteins expressed in the eukaryote Pichia pastoris.	J Biomol NMR	2016
27667693	Computational Repacking of HIF-2Î± Cavity Replaces Water-Based Stabilized Core.	Structure	2016
27595394	Targeting renal cell carcinoma with a HIF-2 antagonist.	Nature	2016
27524295	Basis of Mutual Domain Inhibition in a Bacterial Response Regulator.	Cell Chem Biol	2016
26775787	Superficial liposarcoma: A retrospective review of 13 cases.	J Am Acad Dermatol	2016
26739938	On the acquisition and analysis of microscale thermophoresis data.	Anal Biochem	2016
26929367	Functional and topological diversity of LOV domain photoreceptors.	Proc Natl Acad Sci U S A	2016
25627682	Coiled-coil coactivators play a structural role mediating interactions in hypoxia-inducible factor heterodimerization.	J Biol Chem	2015
26356849	Upstaging From Melanoma in Situ to Invasive Melanoma on the Head and Neck After Complete Surgical Resection.	Dermatol Surg	2015
26226049	Isoform-Selective and Stereoselective Inhibition of Hypoxia Inducible Factor-2.	J Med Chem	2015
26025061	Methyl labeling and TROSY NMR spectroscopy of proteins expressed in the eukaryote Pichia pastoris.	J Biomol NMR	2015
25629646	Ligand-induced folding of a two-component signaling receiver domain.	Biochemistry	2015
24413462	An optogenetic gene expression system with rapid activation and deactivation kinetics.	Nat Chem Biol	2014
25468971	Full-length structure of a monomeric histidine kinase reveals basis for sensory regulation.	Proc Natl Acad Sci U S A	2014
23376100	Solution structure of the WNK1 autoinhibitory domain, a WNK-specific PF2 domain.	J Mol Biol	2013
24346350	Effectors of animal and plant pathogens use a common domain to bind host phosphoinositides.	Nat Commun	2013
23992349	Blue light-induced dimerization of a bacterial LOV-HTH DNA-binding protein.	Biochemistry	2013
23962115	Tumor-induced osteomalacia resulting from primary cutaneous phosphaturic mesenchymal tumor: a case and review of the medical literature.	J Cutan Pathol	2013
23806044	Blue light regulated two-component systems: enzymatic and functional analyses of light-oxygen-voltage (LOV)-histidine kinases and downstream response regulators.	Biochemistry	2013
23407663	Signaling mechanisms of LOV domains: new insights from molecular dynamics studies.	Photochem Photobiol Sci	2013
23434853	Allosteric inhibition of hypoxia inducible factor-2 with small molecules.	Nat Chem Biol	2013
23240775	Regulating the ARNT/TACC3 axis: multiple approaches to manipulating protein/protein interactions with small molecules.	ACS Chem Biol	2013
23363003	Development of inhibitors of the PAS-B domain of the HIF-2Î± transcription factor.	J Med Chem	2013
22648410	Hemerythrin-like domain within F-box and leucine-rich repeat protein 5 (FBXL5) communicates cellular iron and oxygen availability by distinct mechanisms.	J Biol Chem	2012
23205774	Identification of natural and artificial DNA substrates for light-activated LOV-HTH transcription factor EL222.	Biochemistry	2012
22955930	In support of the BMRB.	Nat Struct Mol Biol	2012
22735643	Enlightening molecular mechanisms through study of protein interactions.	J Mol Cell Biol	2012
22442470	Plant science. How plants see the invisible.	Science	2012
21141905	Tripping the light fantastic: blue-light photoreceptors as examples of environmentally modulated protein-protein interactions.	Biochemistry	2011
21923139	Variations in protein-flavin hydrogen bonding in a light, oxygen, voltage domain produce non-Arrhenius kinetics of adduct decay.	Biochemistry	2011
21947910	Special issue as a tribute to Lewis E Kay on his 50th birthday.	J Biomol NMR	2011
21512126	Coactivators necessary for transcriptional output of the hypoxia inducible factor, HIF, are directly recruited by ARNT PAS-B.	Proc Natl Acad Sci U S A	2011

1 - 50 of 118

Anthony P Duff

Bragg Institute

Career Start Year 2000

Number of shared co-authors 1

Mark J S Kelly

Department of Pharmaceutical Chemistry, University of California San Francisco

Career Start Year 2000

Number of shared co-authors 5

Ann H Kwan

The University of Sydney

Career Start Year 2000

Number of shared co-authors 1

Jeffrey B Bonanno

Albert Einstein College of Medicine

Career Start Year 1999

Number of shared co-authors 4

Sergey M Vorobiev

Columbia University

Career Start Year 1998

Number of shared co-authors 1

Witek Kwiatkowski

Swiss Federal Institute of Technology

Career Start Year 1996

Number of shared co-authors 1

Volker D??tsch

Institute for Biophysical Chemistry, Goethe-University

Career Start Year 1995

Number of shared co-authors 6

Clemens Vonrhein

Global Phasing Ltd

Career Start Year 1995

Number of shared co-authors 2

Orly Dym

Weizmann Institute of Science

Career Start Year 1995

Number of shared co-authors 4

Andreas Bracher

Max-Planck-Institute of Biochemistry

Career Start Year 1995

Number of shared co-authors 2

Michael A Kennedy

Miami University

Career Start Year 1993

Number of shared co-authors 6

Gye Won Han

Bridge Institute, University of Southern California

Career Start Year 1991

Number of shared co-authors 1

Marco Nardini

University of Milano

Career Start Year 1991

Number of shared co-authors 0

Maria Sunnerhagen

Linkoping University

Career Start Year 1989

Number of shared co-authors 5

P??r Nordlund

Karolinska Institutet, BioClinicum J6

Career Start Year 1989

Number of shared co-authors 3

Steven C Almo

Albert Einstein College of Medicine

Career Start Year 1988

Number of shared co-authors 5

John F Hunt

Columbia University

Career Start Year 1986

Number of shared co-authors 4

Thomas B Acton

Center for Advanced Biotechnology and Medicine, The State University of New Jersey

Career Start Year 1986

Number of shared co-authors 5

Mark R Chance

Case Western Reserve University

Career Start Year 1986

Number of shared co-authors 3

Aled M Edwards

University of Toronto

Career Start Year 1984

Number of shared co-authors 6

John Kuriyan

University of California berkeley

Career Start Year 1982

Number of shared co-authors 4

Stephen K Burley

The State University of New Jersey

Career Start Year 1982

Number of shared co-authors 11

Gaetano T Montelione

Rensselaer Polytechnic Institute

Career Start Year 1981

Number of shared co-authors 14

Peter Bayer

University of Duisburg-Essen

Career Start Year 1981

Number of shared co-authors 3

Hans J Vogel

University of Calgary

Career Start Year 1979

Number of shared co-authors 1

Tom Alber

University of California berkeley

Career Start Year 1976

Number of shared co-authors 3

George N Phillips

Rice University

Career Start Year 1974

Number of shared co-authors 6

David Cowburn

Albert Einstein College of Medicine

Career Start Year 1969

Number of shared co-authors 4

Wayne A Hendrickson

Columbia University

Career Start Year 1968

Number of shared co-authors 1

Robert M Stroud

University of California San Francisco

Career Start Year 1965

Number of shared co-authors 3

row(s) 1 - 30 of 30

Lewis E Kay

University of Toronto

Co-authored papers 9

Michael K Rosen

UT Southwestern Medical Center

Co-authored papers 9

Diana R Tomchick

University of Texas Southwestern Medical Center

Co-authored papers 4

Peter L Freddolino

University of Michigan ann arbor

Co-authored papers 2

John B MacMillan

University of California

Co-authored papers 2

Chad A Brautigam

UT Southwestern Medical Center

Co-authored papers 2

Rustam Ali

Howard Hughes Medical Institute, UT Southwestern Medical Center

Co-authored papers 2

Anna Reade

Cardiovascular Research Institute, University of California san francisco

Co-authored papers 2

Steven M Patrie

Northwestern University

Co-authored papers 2

Josep Rizo

University of Texas Southwestern Medical Center

Co-authored papers 2

Andrej Sali (CM4AI)

University of California San Francisco

Co-authored papers 1

Tony Pawson

Co-authored papers 1

David A Case

Rutgers University

Co-authored papers 1

Brian Kuhlman

Co-authored papers 1

Oliver F Lange

Center for Integrated Protein Science, Technische Universitat Munchen

Co-authored papers 1

Gordon C K Roberts

Leicester Institute of Structural and Chemical Biology, University of Leicester

Co-authored papers 1

Mike P Williamson

The University of Sheffield

Co-authored papers 1

Lu-Yun Lian

Institute of Systems, The University of Liverpool

Co-authored papers 1

Jenny Chang-Claude

German Cancer Research Center (DKFZ)

Co-authored papers 1

Igor L Barsukov

Institute of Integrative Biology, University of Liverpool

Co-authored papers 1

David E Shaw

Columbia University

Co-authored papers 1

Ad Bax

National Institutes of Health

Co-authored papers 1

Patrick C A van der Wel

Zernike Institute for Advanced Materials, University of Groningen

Co-authored papers 1

David Middleton

Co-authored papers 1

Ioannis Vakonakis

University of Oxford

Co-authored papers 1

Ronald D Seidel

Albert Einstein College of Medicine

Co-authored papers 1

Thomas A Frenkiel

The Medical Research Council Biomedical NMR Centre, The Francis Crick Institute

Co-authored papers 1

Ernest D Laue

University of Cambridge

Co-authored papers 1

Gordon S Rule

Carnegie Mellon University

Co-authored papers 1

Stephen Matthews

Imperial College London

Co-authored papers 1

1 - 30

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