Author details

Full Name

Sirpa Jalkanen

Affiliation

ORCID

Career Start Year

1983

Papers

390

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36463086	Lymph node lymphatic endothelial cells as multifaceted gatekeepers in the immune system.	Trends in Immunology	2023
36302655	Preclinical Evaluation of Zr-Desferrioxamine-Bexmarilimab, a Humanized Antibody Against Common Lymphatic Endothelial and Vascular Endothelial Receptor-1, in a Rabbit Model of Renal Fibrosis.		2023
36384659	Inflammatory Diseases, Inflammatory Biomarkers, and Alzheimer Disease: An Observational Analysis and Mendelian Randomization.	Neurology	2023
37758963	Vascular adhesion protein-1-targeted PET imaging in autoimmune myocarditis.		2023
37568687	Prognostic Values of Tissue and Serum Angiogenic Growth Factors Depend on the Phenotypic Subtypes of Colorectal Cancer.		2023
37468364	Serum cytokine profiles in patients with pancreatic cancer and chronic pancreatitis.		2023
36754910	Newly identified form of phenotypic plasticity of cancer: immunogenic mimicry.	Cancer Metastasis Rev	2023
36626867	Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1<sup>+</sup> T lymphocyte niches through a feed-forward loop.	Cancer Cell	2023
36936266	The interplay between inflammatory cytokines and cardiometabolic disease: bi-directional mendelian randomisation study.	BMJ Med	2023
36801832	Inflammatory proteomics profiling for prediction of incident atrial fibrillation.		2023
37433843	Aerobic exercise training and gut microbiome-associated metabolic shifts in women with overweight: a multi-omic study.		2023
36927455	Polymorphism in interferon alpha/beta receptor contributes to glucocorticoid response and outcome of ARDS and COVID-19.		2023
35212809	CD73 controls ocular adenosine levels and protects retina from light-induced phototoxicity.	Cellular and Molecular Life Sciences	2022
36179016	Autoantibodies to Type I Interferons: The Chicken or the Egg?	Journal of Interferon and Cytokine Research	2022
36176983	Increased atherosclerotic plaque in AOC3 knock-out in ApoE mice and characterization of AOC3 in atherosclerotic human coronary arteries.	Frontiers in Cardiovascular Medicine	2022
36230610	BRAF Expression in Thyrocytes Causes Recruitment of Immunosuppressive STABILIN-1 Macrophages.	Cancers	2022
35500016	Nonclinical Characterization of Bexmarilimab, a Clever-1-Targeting Antibody for Supporting Immune Defense Against Cancers.	Molecular Cancer Therapeutics	2022
35874707	[Ga]Ga-DOTA-Siglec-9 Detects Pharmacodynamic Changes of FAP-Targeted IL2 Variant Immunotherapy in B16-FAP Melanoma Mice.	Frontiers in Immunology	2022
35929612	Small-Molecule-based Supramolecular Plastics Mediated by Liquid-Liquid Phase Separation.	Angewandte Chemie - International Edition	2022
35361620	A plasma metabolite score of three eicosanoids predicts incident type 2 diabetes: a prospective study in three independent cohorts.	BMJ Open Diabetes Research and Care	2022
36423635	Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1<sup>+</sup> T lymphocyte niches through a feed-forward loop.	Cancer Cell	2022
35034144	Pancreatic cancer survival prediction via inflammatory serum markers.	Cancer Immunology, Immunotherapy	2022
35003105	Extracellular ATP Limits Homeostatic T Cell Migration Within Lymph Nodes.	Front Immunol	2021
33491305	The Role of Inflammatory Cytokines as Intermediates in the Pathway from Increased Adiposity to Disease.	Obesity (Silver Spring)	2021
34078651	Systemic Blockade of Clever-1 Elicits Lymphocyte Activation Alongside Checkpoint Molecule Downregulation in Patients with Solid Tumors: Results from a Phase I/II Clinical Trial.	Clinical Cancer Research	2021
33746947	Lymphatic Endothelial Cell Activation and Dendritic Cell Transmigration Is Modified by Genetic Deletion of Clever-1.	Frontiers in Immunology	2021
33472663	Efficacy and tolerability of folate-aminopterin therapy in a rat focal model of multiple sclerosis.	Journal of Neuroinflammation	2021
33517400	Genome-wide association study of circulating interleukin 6 levels identifies novel loci.	Hum Mol Genet	2021
33619304	A prognostic model for colorectal cancer based on CEA and a 48-multiplex serum biomarker panel.	Scientific Reports	2021
33868280	Why Haven't We Found an Effective Treatment for COVID-19?	Frontiers in Immunology	2021
33973512	Intravenous Interferon-Î²1a for the Treatment of Ischemia-Reperfusion Injury in Acute Myocardial Infarct in Pigs.	Heart Surgery Forum	2021
32712883	Obesity of mice lacking VAP-1/SSAO by Aoc3 gene deletion is reproduced in mice expressing a mutated vascular adhesion protein-1 (VAP-1) devoid of amine oxidase activity.	Journal of Physiology and Biochemistry	2021
32817143	First-in-Humans Study of Ga-DOTA-Siglec-9, a PET Ligand Targeting Vascular Adhesion Protein 1.		2021
32970335	CD73 contributes to anti-inflammatory properties of afferent lymphatic endothelial cells in humans and mice.	European Journal of Immunology	2021
32676968	Prognostic impact of CD73 expression and its relationship to PD-L1 in patients with radically treated pancreatic cancer.	Virchows Archiv	2021
33112477	Self-Synthesizing Nanorods from Dynamic Combinatorial Libraries against Drug Resistant Cancer.	Angewandte Chemie - International Edition	2021
33421111	Risky emotional family environment in childhood and depression-related cytokines in adulthood: The protective role of compassion.	Dev Psychobiol	2021
34782683	Red blood cell transfusion induces abnormal HIF-1Î± response to cytokine storm after adult cardiac surgery.	Scientific Reports	2021
34719737	Vascular adhesion protein-1 defines a unique subpopulation of human hematopoietic stem cells and regulates their proliferation.	Cell Mol Life Sci	2021
34374322	Stabilin-1 plays a protective role against Listeria monocytogenes infection through the regulation of cytokine and chemokine production and immune cell recruitment.	Virulence	2021
34885098	Stage I-IV Colorectal Cancer Prognosis Can Be Predicted by Type and Number of Intratumoral Macrophages and CLEVER-1 Vessel Density.	Cancers	2021
32943749	Immunophenotype based on inflammatory cells, PD-1/PD-L1 signalling pathway and M2 macrophages predicts survival in gastric cancer.	British Journal of Cancer	2020
32430515	Glucocorticoids inhibit type I IFN beta signaling and the upregulation of CD73 in human lung.	Intensive Care Med	2020
31646483	Histochemical Approach for Simultaneous Detection of Ectonucleotidase and Alkaline Phosphatase Activities in Tissues.	Methods in Molecular Biology	2020
32426372	A Single-Cell Transcriptional Roadmap of the Mouse and Human Lymph Node Lymphatic Vasculature.	Frontiers in Cardiovascular Medicine	2020
32317394	Compartmentalization of adenosine metabolism in cancer cells and its modulation during acute hypoxia.	Journal of Cell Science	2020
32065831	Effect of Intravenous Interferon Î²-1a on Death and Days Free From Mechanical Ventilation Among Patients With Moderate to Severe Acute Respiratory Distress Syndrome: A Randomized Clinical Trial.	JAMA	2020
32178384	Human Copper-Containing Amine Oxidases in Drug Design and Development.	Molecules	2020
31772321	Robo4 contributes to the turnover of Peyer's patch B cells.	Mucosal Immunology	2020
32094869	Lymphatic endothelial cells of the lymph node.	Nature Reviews Immunology	2020