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Author Details

Sander R van Hooff
Princess Maxima Center for Pediatric Oncology
2008
38
22
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37020198The potential of PARP as a therapeutic target across pediatric solid malignancies.BMC Cancer2023
37528411Effective methods for bulk RNA-seq deconvolution using scnRNA-seq transcriptomes.Genome Biol2023
37540673Two opposing gene expression patterns within ATRX aberrant neuroblastoma.PLoS One2023
34963094Target Actionability Review: a systematic evaluation of replication stress as a therapeutic target for paediatric solid malignancies.Eur J Cancer2022
36182817Implementation of paediatric precision oncology into clinical practice: The Individualized Therapies for Children with cancer program 'iTHER'.Eur J Cancer2022
36237330Chromosome 11q loss and <i>MYCN</i> amplification demonstrate synthetic lethality with checkpoint kinase 1 inhibition in neuroblastoma.Front Oncol2022
34117376BCL-XL is crucial for progression through the adenoma-to-carcinoma sequence of colorectal cancer.Cell Death Differ2021
33547074Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell.Sci Adv2021
33673003AKT3 Expression in Mesenchymal Colorectal Cancer Cells Drives Growth and Is Associated with Epithelial-Mesenchymal Transition.Cancers (Basel)2021
34408135Adipose stem cell niche reprograms the colorectal cancer stem cell metastatic machinery.Nat Commun2021
34433038Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors.Cell Rep2021
34575700αβ-T Cells Engineered to Express γδ-T Cell Receptors Can Kill Neuroblastoma Organoids Independent of MHC-I Expression.J Pers Med2021
31526760Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis.Cancer Cell2019
30151914Capturing colorectal cancer inter-tumor heterogeneity in patient-derived xenograft (PDX) models.Int J Cancer2019
29305587Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models.Cell Death Differ2018
28692036Neoadjuvant chemotherapy affects molecular classification of colorectal tumors.Oncogenesis2017
28368388Methylation of WNT target genes AXIN2 and DKK1 as robust biomarkers for recurrence prediction in stage II colon cancer.Oncogenesis2017
26733613A Validated Prognostic Multigene Expression Assay for Overall Survival in Resected Colorectal Cancer Liver Metastases.Clin Cancer Res2016
27221051TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype.EMBO Mol Med2016
27157610A multidimensional network approach reveals microRNAs as determinants of the mesenchymal colorectal cancer subtype.Oncogene2016
26797113An endometrial gene expression signature accurately predicts recurrent implantation failure after IVF.Sci Rep2016
24764155Nodal metastasis and survival in oral cancer: Association with protein expression of SLPI, not with LCN2, TACSTD2, or THBS2.Head Neck2015
26700642A high-resolution gene expression atlas of epistasis between gene-specific transcription factors exposes potential mechanisms for genetic interactions.BMC Biol2015
26160848ErbB-3 activation by NRG-1β sustains growth and promotes vemurafenib resistance in BRAF-V600E colon cancer stem cells (CSCs).Oncotarget2015
26022646The Co-Expression of Kallikrein 5 and Kallikrein 7 Associates with Poor Survival in Non-HPV Oral Squamous-Cell Carcinoma.Pathobiology2015
24766815Large-scale genetic perturbations reveal regulatory networks and an abundance of gene-specific repressors.Cell2014
23441134PDGFRB promotes liver metastasis formation of mesenchymal-like colorectal tumor cells.Neoplasia2013
24002600Maspin is a marker for early recurrence in primary stage III and IV colorectal cancer.Br J Cancer2013
21976730Tight cooperation between Mot1p and NC2β in regulating genome-wide transcription, repression of transcription following heat shock induction and genetic interaction with SAGA.Nucleic Acids Res2012
23185333Exploring gene expression signatures for predicting disease free survival after resection of colorectal cancer liver metastases.PLoS One2012
23182196Novel diagnostic modalities for assessment of the clinically node-negative neck in oral squamous-cell carcinoma.Lancet Oncol2012
23028359Two distinct repressive mechanisms for histone 3 lysine 4 methylation through promoting 3'-end antisense transcription.PLoS Genet2012
23045589Validation of a gene expression signature for assessment of lymph node metastasis in oral squamous cell carcinoma.J Clin Oncol2012
21596317The specificity and topology of chromatin interaction pathways in yeast.Mol Cell2011
21145464Functional overlap and regulatory links shape genetic interactions between signaling pathways.Cell2010
19320556The construction of genome-based transcriptional units.OMICS2009
19401678Adaptable gene-specific dye bias correction for two-channel DNA microarrays.Mol Syst Biol2009
18689827Organization and integration of biomedical knowledge with concept maps for key peroxisomal pathways.Bioinformatics2008
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Collaborators

Frank C P Holstege
Princess Maxima Center for Pediatric Oncology
Co-authored papers 15
Jan Paul Medema
Oncode Institute
Co-authored papers 11
Jan J Molenaar
Co-authored papers 9
Dik van Leenen
Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University
Co-authored papers 8
Marian J A Groot Koerkamp
Princess Maxima Center for Pediatric Oncology Research
Co-authored papers 7
Thanasis Margaritis
Princess Maxima Center for Pediatric Oncology
Co-authored papers 6
Patrick Kemmeren
Princess Maxima Center for Pediatric Oncology
Co-authored papers 6
Philip Lijnzaad
Princess Maxima Center for Pediatric Oncology
Co-authored papers 6
Mariel O Brok
Princess Maxima Center for Pediatric Oncology
Co-authored papers 5
Jan Koster
Amsterdam University Medical Centers location AMC
Co-authored papers 5
Louis Vermeulen
Oncode Institute
Co-authored papers 5
Joris J Benschop
Center for Molecular Medicine, University Medical Center Utrecht
Co-authored papers 5
Nathalie Brabers
University Medical Centre Utrecht, Universiteitsweg
Co-authored papers 5
Marcel Kool
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 4
Tineke L Lenstra
the Netherlands Cancer Institute, Oncode Institute
Co-authored papers 4
Katrin Sameith
Center for Molecular and Cellular Bioengineering
Co-authored papers 4
Cheuk W Ko
University Medical Centre Utrecht, Universiteitsweg
Co-authored papers 4
Paul J van Diest
University Medical Center Utrecht
Co-authored papers 3
Sake van Wageningen
Oncode Institute, The Netherlands Cancer Institute
Co-authored papers 3
Berend Snel
Utrecht University
Co-authored papers 3
Loes A L van de Pasch
University Medical Centre Utrecht, Universiteitsweg
Co-authored papers 3
Eva Apweiler
University Medical Centre Utrecht, Universiteitsweg
Co-authored papers 3
Stefan M Pfister
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 3
Ruud H Brakenhoff
Vrije Universiteit Amsterdam
Co-authored papers 2
Natalie J??ger
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 2
Antony J Miles
University Medical Centre Utrecht, Universiteitsweg
Co-authored papers 2
Linda V Bakker
Wageningen University and Research
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Hans Clevers
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Release 1.2