Author details

Full Name

Sergei Borukhov

Affiliation

Rowan University School of Osteopathic Medicine

ORCID

Career Start Year

1985

Papers

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
37333075	Single-molecule studies reveal the off-pathway elemental pause state as a target of streptolydigin inhibition of RNA polymerase and its dramatic enhancement by Gre factors.	bioRxiv	2023
35927234	Interaction between transcribing RNA polymerase and topoisomerase I prevents R-loop formation in E. coli.	Nat Commun	2022
35609997	GNATÂ toxins evolve toward narrow tRNA target specificities.	Nucleic Acids Res	2022
33208949	Structure and function of virion RNA polymerase of a crAss-like phage.	Nature	2021
32265328	Histidine-Triad Hydrolases Provide Resistance to Peptide-Nucleotide Antibiotics.	mBio	2020
32597957	Mechanism of translation inhibition by type II GNAT toxin AtaT2.	Nucleic Acids Res	2020
29931259	Escherichia coli ItaT is a type II toxin that inhibits translation by acetylating isoleucyl-tRNAIle.	Nucleic Acids Res	2018
28370550	Studying transcription initiation by RNA polymerase with diffusion-based single-molecule fluorescence.	Protein Sci	2017
28332923	Different types of pausing modes during transcription initiation.	Transcription	2017
28402520	A non-canonical multisubunit RNA polymerase encoded by the AR9 phage recognizes the template strand of its uracil-containing promoters.	Nucleic Acids Res	2017
27729537	Backtracked and paused transcription initiation intermediate of Escherichia coli RNA polymerase.	Proc Natl Acad Sci U S A	2016
27882317	Bacterial RNA Polymerase-DNA Interaction-The Driving Force of Gene Expression and the Target for Drug Action.	Front Mol Biosci	2016
26604313	DksA regulates RNA polymerase in Escherichia coli through a network of interactions in the secondary channel that includes Sequence Insertion 1.	Proc Natl Acad Sci U S A	2015
26490960	A non-canonical multisubunit RNA polymerase encoded by a giant bacteriophage.	Nucleic Acids Res	2015
25026542	The molecular mechanism of aminopropylation of peptide-nucleotide antibiotic microcin C.	J Am Chem Soc	2014
25311862	Coupling of downstream RNA polymerase-promoter interactions with formation of catalytically competent transcription initiation complex.	J Mol Biol	2014
19854830	Early transcriptional arrest at Escherichia coli rplN and ompX promoters.	J Biol Chem	2009
19894614	[Mechanisms of action of RNA polymerase-binding transcription factors that do not bind to DNA].	Biofizika	2009
18280161	RNA polymerase: the vehicle of transcription.	Trends Microbiol	2008
17462013	Control of the respiratory metabolism of Thermus thermophilus by the nitrate respiration conjugative element NCE.	Mol Microbiol	2007
18158897	An allosteric path to transcription termination.	Mol Cell	2007
17766423	Analysis of promoter targets for Escherichia coli transcription elongation factor GreA in vivo and in vitro.	J Bacteriol	2007
16628221	pH-dependent conformational switch activates the inhibitor of transcription elongation.	EMBO J	2006
16765888	Single-molecule approaches reveal the idiosyncrasies of RNA polymerases.	Structure	2006
15720542	Bacterial transcription elongation factors: new insights into molecular mechanism of action.	Mol Microbiol	2005
16122422	Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation.	Cell	2005
15950164	RNA polymerase structure and function at lac operon.	C R Biol	2005
15200953	Molecular mechanism of transcription inhibition by peptide antibiotic Microcin J25.	Mol Cell	2004
15601822	Release of initiation factors from 48S complexes during ribosomal subunit joining and the link between establishment of codon-anticodon base-pairing and hydrolysis of eIF2-bound GTP.	Genes Dev	2004
12732296	RNA polymerase holoenzyme: structure, function and biological implications.	Curr Opin Microbiol	2003
14712703	Biochemical assays of Gre factors of Thermus thermophilus.	Methods Enzymol	2003
12970184	Transcription through the roadblocks: the role of RNA polymerase cooperation.	EMBO J	2003
14633991	Transcript cleavage factors GreA and GreB act as transient catalytic components of RNA polymerase.	EMBO J	2003
12000971	Crystal structure of a bacterial RNA polymerase holoenzyme at 2.6 A resolution.	Nature	2002
12198314	Purification, crystallization and initial crystallographic analysis of RNA polymerase holoenzyme from Thermus thermophilus.	Acta Crystallogr D Biol Crystallogr	2002
12455702	Role of the RNA polymerase sigma subunit in transcription initiation.	Res Microbiol	2002
11586920	Escherichia coli transcript cleavage factors GreA and GreB: functions and mechanisms of action.	Methods Enzymol	2001
10777576	The functional role of basic patch, a structural element of Escherichia coli transcript cleavage factors GreA and GreB.	J Biol Chem	2000
11095736	The specificity loop of T7 RNA polymerase interacts first with the promoter and then with the elongating transcript, suggesting a mechanism for promoter clearance.	Proc Natl Acad Sci U S A	2000
9732867	Eukaryotic ribosomes require initiation factors 1 and 1A to locate initiation codons.	Nature	1998
9512710	Distinct functions of N and C-terminal domains of GreA, an Escherichia coli transcript cleavage factor.	J Mol Biol	1998
9698562	Visualization of the binding site for the transcript cleavage factor GreB on Escherichia coli RNA polymerase.	J Mol Biol	1998
9054416	Domain organization of Escherichia coli transcript cleavage factors GreA and GreB.	J Biol Chem	1997
8902815	Purification and assay of Escherichia coli transcript cleavage factors GreA and GreB.	Methods Enzymol	1996
8902816	Histidine-tagged RNA polymerase of Escherichia coli and transcription in solid phase.	Methods Enzymol	1996
7538676	Intrinsic transcript cleavage activity of RNA polymerase.	Proc Natl Acad Sci U S A	1995
7854424	Crystal structure of the GreA transcript cleavage factor from Escherichia coli.	Nature	1995
7932713	Crystallization of GreA, a transcript cleavage factor from Escherichia coli.	J Mol Biol	1994
8226874	Two modes of transcription initiation in vitro at the rrnB P1 promoter of Escherichia coli.	J Biol Chem	1993
8431948	Transcript cleavage factors from E. coli.	Cell	1993

1 - 50 of 69

Teit Max Moscote S??gaard

Expres2ion Biotechnologies

Career Start Year 1998

Number of shared co-authors 0

Rachel A Mooney

University of Wisconsin-Madison

Career Start Year 1997

Number of shared co-authors 4

Miki Jishage

The Rockefeller University

Career Start Year 1995

Number of shared co-authors 1

Min Zhou

College of Materials Science and Engineering, Hunan University

Career Start Year 1994

Number of shared co-authors 2

David A Bushnell

Stanford University

Career Start Year 1994

Number of shared co-authors 2

Ralph E Davis

Stanford University School of Medicine

Career Start Year 1988

Number of shared co-authors 1

Scott A Lesley

Merck & Co., Inc.

Career Start Year 1987

Number of shared co-authors 2

Jennifer A Doudna

Innovative Genomics Institute, University of California berkeley

Career Start Year 1987

Number of shared co-authors 3

Donald D Lorimer

Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Career Start Year 1986

Number of shared co-authors 1

Tomohiro Tamura

National Institute of Advanced Industrial Science and Technology (AIST)

Career Start Year 1985

Number of shared co-authors 1

Mike O'Donnell

The Rockefeller University

Career Start Year 1985

Number of shared co-authors 1

Nicholas Ambulos

University of Maryland School of Medicine

Career Start Year 1984

Number of shared co-authors 0

Opher Gileadi

Structural Genomics Consortium Karolinska Institute Stockholm Sweden.

Career Start Year 1984

Number of shared co-authors 2

Aled M Edwards

University of Toronto

Career Start Year 1984

Number of shared co-authors 3

James C Hu

Texas A&M University and Texas Agrilife Research, College Station

Career Start Year 1983

Number of shared co-authors 4

Udo Heinemann

Max-Delbruck-Center for Molecular Medicine in the Helmholtz Association (MDC)

Career Start Year 1980

Number of shared co-authors 2

Andrzej Joachimiak

Center for Structural Biology of Infectious Diseases, University of Chicago

Career Start Year 1979

Number of shared co-authors 2

Michael Brenowitz

Albert Einstein College of Medicine

Career Start Year 1979

Number of shared co-authors 1

Kalappa Muniyappa

Indian Institute of Science

Career Start Year 1979

Number of shared co-authors 0

Deborah A Siegele

Texas A&M University, College Station

Career Start Year 1979

Number of shared co-authors 2

Gail E Christie

Virginia Commonwealth University

Career Start Year 1977

Number of shared co-authors 1

Ivan Ivanov

Institute of Molecular Biology "Roumen Tsanev",Bulgarian Academy of Sciences

Career Start Year 1974

Number of shared co-authors 0

Jack F Greenblatt

College Street, University of Toronto

Career Start Year 1969

Number of shared co-authors 1

Antoine Danchin

University of Hong Kong

Career Start Year 1969

Number of shared co-authors 0

Sung-Hou Kim

University of California berkeley

Career Start Year 1967

Number of shared co-authors 2

Roger D Kornberg

Stanford University

Career Start Year 1965

Number of shared co-authors 3

Hamilton O Smith

J. Craig Venter Institute

Career Start Year 1964

Number of shared co-authors 0

Glauco P Tocchini-Valentini

Monterotondo Mouse Clinic (MMC), Italian National Research Council (CNR)

Career Start Year 1961

Number of shared co-authors 0

Masayori Inouye

Robert Wood Johnson Medical School, Rutgers University

Career Start Year 1961

Number of shared co-authors 2

David Schlessinger

NIH/National Institute of Ageing

Career Start Year 1960

Number of shared co-authors 0

row(s) 1 - 30 of 30

Seth A Darst

The Rockefeller University

Co-authored papers 5

Mikhail Kashlev

Co-authored papers 4

Marianna Orlova

The Research Institute of the McGill University Health Centre

Co-authored papers 4

D Koulich

State University of New York Health Science Center at Brooklyn 11203

Co-authored papers 3

Dylan J Taatjes

University of Colorado

Co-authored papers 2

Shigeyuki Yokoyama

Shinshu University School of Medicine

Co-authored papers 2

Arun Malhotra

University of Miami Miller School of Medicine

Co-authored papers 2

Brian P Hudson

The State University of New Jersey

Co-authored papers 1

Andrej Sali (CM4AI)

University of California San Francisco

Co-authored papers 1

Barry L Wanner

Harvard Medical School

Co-authored papers 1

Carol A Gross

University of California san francisco

Co-authored papers 1

Robert Landick

University of Wisconsin-Madison

Co-authored papers 1

Anthony L Shiver

Stanford University

Co-authored papers 1

Dina Schneidman-Duhovny

The Hebrew University of Jerusalem

Co-authored papers 1

1 - 14

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