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Author Details

Timothy J Vyse
1987
237
69
PMIDPaper TitleJournal TitlePublished Year
37496418A review of genetic risk in systemic lupus erythematosus.2023
36583554Genetics of SLE: does this explain susceptibility and severity across racial groups?2023
35315246Complement C4, the Major Histocompatibility Complex, and Autoimmunity.Arthritis and Rheumatology2022
36371989Comprehensive genetic and functional analyses of Fc gamma receptors influence on response to rituximab therapy for autoimmunity.EBioMedicine2022
35960817Immunodeficiency, autoimmunity, and increased risk of B cell malignancy in humans with TRAF3 mutations.Sci Immunol2022
36327221COVID-19 and systemic lupus erythematosus genetics: A balance between autoimmune disease risk and protection against infection.PLoS Genet2022
36412098Age acquired skewed X chromosome inactivation is associated with adverse health outcomes in humans.Elife2022
33308445Identification of susceptibility loci for Takayasu arteritis through a large multi-ancestral genome-wide association study.Am J Hum Genet2021
33536424Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups.Nat Commun2021
33676896Nucleolin acts as the receptor for C1QTNF4 and supports C1QTNF4-mediated innate immunity modulation.Journal of Biological Chemistry2021
32719713Independent Replication on Genome-Wide Association Study Signals Identifies as a Novel Locus for Systemic Lupus Erythematosus.Frontiers in Genetics2020
32077931Genome-wide assessment of genetic risk for systemic lupus erythematosus and disease severity.Human Molecular Genetics2020
31826855High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus.Annals of the Rheumatic Diseases2020
32647184Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues.Nature Communications2020
33182226Trans-Ancestral Fine-Mapping and Epigenetic Annotation as Tools to Delineate Functionally Relevant Risk Alleles at and in Systemic Lupus Erythematosus.International Journal of Molecular Sciences2020
31407831Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes.Genet Epidemiol2019
31781109Chronic Immune Activation in Systemic Lupus Erythematosus and the Autoimmune PTPN22 Trp<sup>620</sup> Risk Allele Drive the Expansion of FOXP3<sup>+</sup> Regulatory T Cells and PD-1 Expression.Front Immunol2019
31672989GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways.Nat Commun2019
30573655Genome-wide meta-analysis reveals shared new <i>loci</i> in systemic seropositive rheumatic diseases.Ann Rheum Dis2019
31092820Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus.Nature Communications2019
29576246Autoantibodies targeting TLR and SMAD pathways define new subgroups in systemic lupus erythematosus.Journal of Autoimmunity2018
30053827The plasma biomarker soluble SIGLEC-1 is associated with the type I interferon transcriptional signature, ethnic background and renal disease in systemic lupus erythematosus.2018
29912393A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus.Hum Mol Genet2018
29907525Tissue-Restricted Adaptive Type 2 Immunity Is Orchestrated by Expression of the Costimulatory Molecule OX40L on Group 2 Innate Lymphoid Cells.Immunity2018
30085094Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans.Hum Mol Genet2018
29724251Meta-analysis of GWAS on both Chinese and European populations identifies GPR173 as a novel X chromosome susceptibility gene for SLE.Arthritis Res Ther2018
29625966Identification of , and as loci associated with systemic lupus erythematosus (SLE) and evaluation of SLE genetics in drug repositioning.Annals of the Rheumatic Diseases2018
29177435De novo mutations implicate novel genes in systemic lupus erythematosus.Hum Mol Genet2018
28289186Multiple signals at the extended 8p23 locus are associated with susceptibility to systemic lupus erythematosus.Journal of Medical Genetics2017
28509669Genetic advances in systemic lupus erythematosus: an update.Current Opinion in Rheumatology2017
28818832B cell OX40L supports T follicular helper cell development and contributes to SLE pathogenesis.Annals of the Rheumatic Diseases2017
28686855Large-Scale Identification of Common Trait and Disease Variants Affecting Gene Expression.Am J Hum Genet2017
28640813Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons.PLoS Genet2017
28552197Large-Scale Identification of Common Trait and Disease Variants Affecting Gene Expression.Am J Hum Genet2017
28714469Transancestral mapping and genetic load in systemic lupus erythematosus.Nat Commun2017
28444759Dysregulated CD46 shedding interferes with Th1-contraction in systemic lupus erythematosus.European Journal of Immunology2017
28747257Cells with Treg-specific FOXP3 demethylation but low CD25 are prevalent in autoimmunity.Journal of Autoimmunity2017
29059182Profiling RNA-Seq at multiple resolutions markedly increases the number of causal eQTLs in autoimmune disease.PLoS Genetics2017
27390188Tartrate-Resistant Acid Phosphatase Deficiency in the Predisposition to Systemic Lupus Erythematosus.Arthritis Rheumatol2017
27193031A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus.Annals of the Rheumatic Diseases2017
28062664Mapping eQTLs with RNA-seq reveals novel susceptibility genes, non-coding RNAs and alternative-splicing events in systemic lupus erythematosus.Hum Mol Genet2017
28041642A Genome-wide Association Study Identifies Risk Alleles in Plasminogen and P4HA2 Associated with Giant Cell Arteritis.Am J Hum Genet2017
25180293Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA.Ann Rheum Dis2016
26746423Improved monitoring of clinical response in Systemic Lupus Erythematosus by longitudinal trend in soluble vascular cell adhesion molecule-1.2016
26783109Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production.Ann Rheum Dis2016
27399966Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.Nature Genetics2016
27118513The complement receptor 3 (CD11b/CD18) agonist Leukadherin-1 suppresses human innate inflammatory signalling.Clinical and Experimental Immunology2016
26713507X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome.Arthritis Rheumatol2016
26316170Identification of a New Susceptibility Locus for Systemic Lupus Erythematosus on Chromosome 12 in Individuals of European Ancestry.Arthritis Rheumatol2016
26606652Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.Arthritis Rheumatol2016
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