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Author Details

Nicholas P Farrell
Virginia Commonwealth University, United States of America Massey Cancer Center
1984
228
49
PMIDPaper TitleJournal TitlePublished Year
37182504Glycosaminoglycan-directed cobalt complexes.J Inorg Biochem2023
37552525Probing Disaccharide Binding to Triplatin as Models for Tumor Cell Heparan Sulfate (GAG) Interactions.Inorg Chem2023
37736178A Comparison of Di- and Trinuclear Platinum Complexes Interacting with Glycosaminoglycans for Targeted Chemotherapy.ACS Med Chem Lett2023
34652881A Click Chemistry Approach to Targeted DNA Crosslinking with cis-Platinum(II)-Modified Triplex-Forming Oligonucleotides.Angew Chem Int Ed Engl2022
35640255Controlling Nuclease Degradation of Wireframe DNA Origami with Minor Groove Binders.ACS Nano2022
35367819Substitution-inert polynuclear platinum complexes and Glycosaminoglycans: A molecular dynamics study of its non-covalent interactions.J Inorg Biochem2022
36106109Radiation induces ESCRT pathway dependent CD44v3<sup>+</sup> extracellular vesicle production stimulating pro-tumor fibroblast activity in breast cancer.Front Oncol2022
35131616Metalloglycomics of tris(2,2'-bipyridyl) cobalt and ruthenium compounds.J Inorg Biochem2022
34815360Exploitation of Sulfated Glycosaminoglycan Status for Precision Medicine of Triplatin in Triple-Negative Breast Cancer.Mol Cancer Ther2022
33174390Conformational Modulation of Iduronic Acid-Containing Sulfated Glycosaminoglycans by a Polynuclear Platinum Compound and Implications for Development of Antimetastatic Platinum Drugs.Angew Chem Int Ed Engl2021
34105220On the Biology of Werner's Complex.Angew Chem Int Ed Engl2021
33977992Platinum complexes act as shielding agents against virus infection.Chem Commun (Camb)2021
32432260The leaving group in Au(I)-phosphine compounds dictates cytotoxic pathways in CEM leukemia cells and reactivity towards a Cys<sub>2</sub>His<sub>2</sub> model zinc finger.Dalton Trans2020
31689625Intramolecular platinum migration on a peptide in gas phase during collision-induced dissociation.J Inorg Biochem2020
33132195Substitution-inert polynuclear platinum compounds inhibit human cytomegalovirus attachment and entry.Antiviral Res2020
32712380Modulation of relaxation activity of human topoisomerases by Pt(II)-based complexes.J Inorg Biochem2020
32988198Substitution-Inert Polynuclear Platinum Complexes Inhibit Reverse Transcription Preferentially in RNA Triplex-Forming Templates.Inorg Chem2020
32329497Ru(II)-Naphthoquinone complexes with high selectivity for triple-negative breast cancer.Dalton Trans2020
30565774Substitution-Inert Polynuclear Platinum Complexes Act as Potent Inducers of Condensation/Aggregation of Short Single- and Double-Stranded DNA and RNA Oligonucleotides.Chemistry2019
31354168Biological relevance of interaction of platinum drugs with <i>O</i>-donor ligands.Inorganica Chim Acta2019
31379111Metal ions and the extracellular matrix in tumor migration.FEBS J2019
31231629TriplatinNC and Biomolecules: Building Models Based on Non-covalent Interactions.Front Chem2019
31046253Substitution-Inert Polynuclear Platinum Complexes with Dangling Amines: Condensation/Aggregation of Nucleic Acids and Inhibition of DNA-Related Enzymatic Activities.Inorg Chem2019
30714595Molecular methods for assessment of non-covalent metallodrug-DNA interactions.Chem Soc Rev2019
31070627Influence of geometric isomerism on the binding of platinum anticancer agents with phospholipids.Dalton Trans2019
31089613The facile and visualizable identification of broad-spectrum inhibitors of MDM2/p53 using co-expressed protein complexes.Analyst2019
30632736Glycans as Ligands in Bioinorganic Chemistry. Probing the Interaction of a Trinuclear Platinum Anticancer Complex with Defined Monosaccharide Fragments of Heparan Sulfate.Inorg Chem2019
29242879Translesion DNA synthesis across double-base lesions derived from cross-links of an antitumor trinuclear platinum compound: primer extension, conformational and thermodynamic studies.Metallomics2018
29870126Gold-Catalyzed C-S Aryl-Group Transfer in Zinc Finger Proteins.Angew Chem Int Ed Engl2018
29473748Comparison of Metal-Ammine Compounds Binding to DNA and Heparin. Glycans as Ligands in Bioinorganic Chemistry.Inorg Chem2018
29766623Substitution-Inert Polynuclear Platinum Complexes That Inhibit the Activity of DNA Polymerase in Triplex-Forming Templates.Angew Chem Int Ed Engl2018
29788339Rapid Establishment of a Cold Chain Capacity of -60°C or Colder for the STRIVE Ebola Vaccine Trial During the Ebola Outbreak in Sierra Leone.J Infect Dis2018
29655185Substitution-Inert Polynuclear Platinum Complexes as Metalloshielding Agents for Heparan Sulfate.Chemistry2018
29394023Metalloglycomics.Met Ions Life Sci2018
29394021Polynuclear Platinum Complexes. Structural Diversity and DNA Binding.Met Ions Life Sci2018
29227104X-ray Absorption Spectroscopy Combined with Time-Dependent Density Functional Theory Elucidates Differential Substitution Pathways of Au(I) and Au(III) with Zinc Fingers.Inorg Chem2018
29341369Structural Factors Affecting Binding of Platinum Anticancer Agents with Phospholipids: Influence of Charge and Phosphate Clamp Formation.Chemistry2018
28729428<sup>18</sup>F-Labeled Carboplatin Derivative for PET Imaging of Platinum Drug Distribution.J Nucl Med2017
28451269Enhancement of the physicochemical properties of [Pt(dien)(nucleobase)]<sup>2+</sup> for HIVNCp7 targeting.Chem Sci2017
28451171Antiangiogenic platinum through glycan targeting.Chem Sci2017
28319298Diversity in Gold Finger Structure Elucidated by Traveling-Wave Ion Mobility Mass Spectrometry.Angew Chem Int Ed Engl2017
28937773Probing the HIV-1 NCp7 Nucleocapsid Protein with Site-Specific Gold(I)-Phosphine Complexes.Inorg Chem2017
26861698Suppression of RAF/MEK or PI3K synergizes cytotoxicity of receptor tyrosine kinase inhibitors in glioma tumor-initiating cells.J Transl Med2016
27934299Interaction of the HIV NCp7 Protein with Platinum(II) and Gold(III) Complexes Containing Tridentate Ligands.Inorg Chem2016
27858001Au(iii) compounds as HIV nucleocapsid protein (NCp7)-nucleic acid antagonists.Chem Commun (Camb)2016
27171123Tuning the reactivity of Sp1 zinc fingers with platinum complexes.Dalton Trans2016
27293145Effects of coordination mode of 2-mercaptothiazoline on reactivity of Au(I) compounds with thiols and sulfur-containing proteins.J Inorg Biochem2016
27574114Inhibition of nuclear factor kappaB proteins-platinated DNA interactions correlates with cytotoxic effectiveness of the platinum complexes.Sci Rep2016
25531886[Au(dien)(N-heterocycle)](3+): reactivity with biomolecules and zinc finger peptides.Inorg Chem2015
25972547Two-Year Follow-Up of Macaques Developing Intermittent Control of the Human Immunodeficiency Virus Homolog Simian Immunodeficiency Virus SIVmac251 in the Chronic Phase of Infection.J Virol2015
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Collaborators

Erica J Peterson
Massey Cancer Center, Virginia Commonwealth University
Co-authored papers 24
Bennett Van Houten
UPMC-Hillman Cancer Center, University of Pittsburgh
Co-authored papers 7
Oliver B??gler
American Association for Cancer Research, Henry Ford Hospital, Ludwig Institute for Cancer Research, National Cancer Institute, Salk Institute for Biological Studies, University of Cambridge, University of Texas MD Anderson Cancer Center, Virginia Commonwealth University
Co-authored papers 5
Takashi Shingu
The University of Texas MD Anderson Cancer Center
Co-authored papers 3
Tom Mikkelsen
Ontario Brain Institute
Co-authored papers 2
Ho-Shin Gwak
National Cancer Center
Co-authored papers 2
Christine Billecke
Henry Ford Hospital
Co-authored papers 2
Khatri Latha
Baylor College of Medicine
Co-authored papers 2
Vaibhav Chumbalkar
Moffitt Cancer Center
Co-authored papers 2
W K Alfred Yung
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Muhammad Imran Malik
Interfaculty Institute of Microbiology and Infection Medicine, University of Tubingen
Co-authored papers 1
Ashkhen Movsisyan
Hospital for War Veterans No. 2
Co-authored papers 1
Laura A Gibson
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
YeoHyeon Hwang
University of Texas MD Anderson Cancer Center
Co-authored papers 1
Dimpy Koul
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Anupama E Gururaj
National Institute of Allergy and Infectious Disease, National Institutes of Health
Co-authored papers 1
Joshua Chuck Harrell
Virginia Commonwealth University
Co-authored papers 1
Yaoqi Alan Wang
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Mikhail G Dozmorov
Virginia Commonwealth University
Co-authored papers 1
Cathie G Miller
University of Pennsylvania School of Medicine
Co-authored papers 1
Robert E Dejournett
The University of Texas M.D. Anderson Cancer Center
Co-authored papers 1
Garth Powis
PHusis Therapeutics Inc.
Co-authored papers 1
Keishi Fujiwara
University of Texas M.D. Anderson Cancer Center
Co-authored papers 1
Frederick F Lang
The University of Texas M.D. Anderson Cancer Center
Co-authored papers 1
Susan Finniss
Henry Ford Hospital
Co-authored papers 1
Yves Pommier
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
Branden S Moriarity
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Release 1.2