Author details

Full Name

Berthold GÃ¶ttgens

Affiliation

ORCID

Career Start Year

1992

Papers

305

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37066352	Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes.	bioRxiv	2024
37302069	Proteomic analysis of circulating immune cells identifies cellular phenotypes associated with COVID-19 severity.	Cell Rep	2023
36103728	Introduction to a review series on single-cell genomics: getting ready for clinical impact in leukemia and myeloid neoplasms.	Blood	2023
38038362	Expression profiling of cerebrospinal fluid identifies dysregulated antiviral mechanisms in multiple sclerosis.		2023
37595278	Genome-wide transcription factor-binding maps reveal cell-specific changes in the regulatory architecture of human HSPCs.		2023
37590359	Yolk sac cell atlas reveals multiorgan functions during human early development.	Science	2023
37645930	Autophagy counters inflammation-driven glycolytic impairment in aging hematopoietic stem cells.		2023
37799110	Single-cell multi-omics analysis of COVID-19 patients with pre-existing autoimmune diseases shows aberrant immune responses to infection.		2023
37348497	Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner.	Mol Cell	2023
36650172	A genome-wide relay of signalling-responsive enhancers drives hematopoietic specification.		2023
37464070	Pharmacological inhibition of METTL3 impacts specific haematopoietic lineages.		2023
36809781	Physioxia improves the selectivity of hematopoietic stem cell expansion cultures.	Blood Adv	2023
37322291	An atlas of rabbit development as a model for single-cell comparative genomics.	Nat Cell Biol	2023
37308670	Mapping interindividual dynamics of innate immune response at single-cell resolution.	Nat Genet	2023
35224470	Coagulation factor V is a T-cell inhibitor expressed by leukocytes in COVID-19.	iScience	2022
36048017	EBF1 primes B-lymphoid enhancers and limits the myeloid bias in murine multipotent progenitors.	Journal of Experimental Medicine	2022
36042201	Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia.	Nat Commun	2022
35971894	Identification and characterization of inâ¿¿vitro expanded hematopoietic stem cells.	EMBO Rep	2022
35653588	p57Kip2 regulates embryonic blood stem cells by controlling sympathoadrenal progenitor expansion.	Blood	2022
35393954	TET2 regulates immune tolerance in chronically activated mast cells.	JCI insight	2022
35902769	Mesoderm-derived PDGFRA<sup>+</sup> cells regulate the emergence of hematopoietic stem cells in the dorsal aorta.	Nat Cell Biol	2022
35767701	STAT1 is essential for HSC function and maintains MHCIIhi stem cells that resist myeloablation and neoplastic expansion.	Blood	2022
35701672	Publisher Correction: UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs.	Nat Genet	2022
36163261	Single-cell multi-omics profiling links dynamic DNA methylation to cell fate decisions during mouse early organogenesis.	Genome Biol	2022
35820055	Combining single-cell tracking and omics improves blood stem cell fate regulator identification.	Blood	2022
35817961	Mesp1 controls the chromatin and enhancer landscapes essential for spatiotemporal patterning of early cardiovascular progenitors.	Nat Cell Biol	2022
36184065	Relaxin/insulin-like family peptide receptor 4 (Rxfp4) expressing hypothalamic neurons modulate food intake and preference in mice.	Molecular Metabolism	2022
34341490	Identification of HSC/MPP expansion units in fetal liver by single-cell spatiotemporal transcriptomics.	Cell Research	2022
34489600	Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis.	Nat Biotechnol	2022
35087060	Cholinergic signals preserve haematopoietic stem cell quiescence during regenerative haematopoiesis.	Nature Communications	2022
35073399	Unique molecular and functional features of extramedullary hematopoietic stem and progenitor cell reservoirs in humans.	Blood	2022
34588693	Blood and immune development in human fetal bone marrow and Down syndrome.	Nature	2021
33489472	Single-cell transcriptome analysis of CAR T-cell products reveals subpopulations, stimulation, and exhaustion signatures.	OncoImmunology	2021
33961793	Hematopoietic stem cells retain functional potential and molecular identity in hibernation cultures.	Stem Cell Reports	2021
34225769	Coordinated changes in gene expression kinetics underlie both mouse and human erythroid maturation.	Genome Biol	2021
34057731	Single-Cell Analysis of Hematopoietic Stem Cells.	Methods in Molecular Biology	2021
34051148	Longitudinal analysis reveals that delayed bystander CD8+ TÂ cell activation and early immune pathology distinguish severe COVID-19 from mild disease.	Immunity	2021
33574614	Publisher Correction: The T-box transcription factor Eomesodermin governs haemogenic competence of yolk sac mesodermal progenitors.	Nat Cell Biol	2021
33770496	Reconciling Flux Experiments for Quantitative Modeling of Normal and Malignant Hematopoietic Stem/Progenitor Dynamics.	Stem Cell Reports	2021
33560400	JMJD6 promotes self-renewal and regenerative capacity of hematopoietic stem cells.	Blood advances	2021
34197725	De novo generation of macrophage from placenta-derived hemogenic endothelium.	Dev Cell	2021
33308481	Diverse Routes toward Early Somites in the Mouse Embryo.	Dev Cell	2021
33078414	Single-cell molecular profiling provides a high-resolution map of basophil and mast cell development.	Allergy: European Journal of Allergy and Clinical Immunology	2021
33229891	How haematopoiesis research became a fertile ground for regulatory network biology as pioneered by Eric Davidson.	Current Opinion in Hematology	2021
33420489	The T-box transcription factor Eomesodermin governs haemogenic competence of yolk sac mesodermal progenitors.	Nat Cell Biol	2021
34853826	The EHA Research Roadmap: Normal Hematopoiesis.	HemaSphere	2021
34715054	CITED2 coordinates key hematopoietic regulatory pathways to maintain the HSC pool in both steady-state hematopoiesis and transplantation.	Stem Cell Reports	2021
34941412	Cell-by-cell dissection of phloem development links a maturation gradient to cell specialization.	Science	2021
33230302	Manipulating niche composition limits damage to haematopoietic stem cells during Plasmodium infection.	Nature Cell Biology	2020
32367048	Differentiation of transplanted haematopoietic stem cells tracked by single-cell transcriptomic analysis.	Nat Cell Biol	2020