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Author Details

Hae Kyung Im
1994
79
33
PMIDPaper TitleJournal TitlePublished Year
37164006A joint transcriptome-wide association study across multiple tissues identifies candidate breast cancer susceptibility genes.2023
37663543Revealing polygenic pleiotropy using genetic risk scores for asthma.HGG Adv2023
37409955Predicted Proteome Association Studies of Breast, Prostate, Ovarian, and Endometrial Cancers Implicate Plasma Protein Regulation in Cancer Susceptibility.Cancer Epidemiol Biomarkers Prev2023
36798214Multivariate adaptive shrinkage improves cross-population transcriptome prediction for transcriptome-wide association studies in underrepresented populations.bioRxiv2023
36608684Probabilistic integration of transcriptome-wide association studies and colocalization analysis identifies key molecular pathways of complex traits.2023
35027082Polygenic transcriptome risk scores (PTRS) can improve portability of polygenic risk scores across ancestries.Genome Biol2022
35385699Polygenic transcriptome risk scores for COPD and lung function improve cross-ethnic portability of prediction in the NHLBI TOPMed program.Am J Hum Genet2022
36344522Discerning asthma endotypes through comorbidity mapping.Nat Commun2022
35606880Fine-mapping studies distinguish genetic risks for childhood- and adult-onset asthma in the HLA region.Genome Med2022
33308443Probabilistic colocalization of genetic variants from complex and molecular traits: promise and limitations.Am J Hum Genet2021
33937878Transcriptome prediction performance across machine learning models and diverse ancestries.Human Genetics and Genomics Advances2021
33658504A scalable unified framework of total and allele-specific counts for cis-QTL, fine-mapping, and prediction.Nature Communications2021
33499903Exploiting the GTEx resources to decipher the mechanisms at GWAS loci.Genome Biol2021
32912253PTWAS: investigating tissue-relevant causal molecular mechanisms of complex traits using probabilistic TWAS analysis.2020
32492425Analysis of Genetically Regulated Gene Expression Identifies a Prefrontal PTSD Gene, SNRNP35, Specific to Military Cohorts.Cell Rep2020
32917697PhenomeXcan: Mapping the genome to the phenome through the transcriptome.Sci Adv2020
32964524Fine-mapping and QTL tissue-sharing information improves the reliability of causal gene identification.Genetic Epidemiology2020
32913075Cell type-specific genetic regulation of gene expression across human tissues.Science2020
32913072The impact of sex on gene expression across human tissues.Science2020
32912314sn-spMF: matrix factorization informs tissue-specific genetic regulation of gene expression.Genome Biol2020
31249589A <i>Trans</i>-Ethnic Genome-Wide Association Study of Uterine Fibroids.Front Genet2019
30395166ukbREST: efficient and streamlined data access for reproducible research in large biobanks.Bioinformatics2019
30624610Functionally oriented analysis of cardiometabolic traits in a trans-ethnic sample.Hum Mol Genet2019
30926968Opportunities and challenges for transcriptome-wide association studies.Nat Genet2019
31036433Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.Lancet Respir Med2019
31086353Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.Nat Genet2019
30668570Integrating predicted transcriptome from multiple tissues improves association detection.PLoS Genet2019
29229983Annotation-free quantification of RNA splicing using LeafCutter.Nature Genetics2018
30061609Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.Nat Commun2018
30054336A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk.Cancer Res2018
30096133Genetic architecture of gene expression traits across diverse populations.PLoS Genetics2018
29739930Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics.Nat Commun2018
29360107Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.Sci Data2018
29257133Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.Sci Data2017
28957356Trans-ethnic predicted expression genome-wide association analysis identifies a gene for estrogen receptor-negative breast cancer.PLoS Genetics2017
28341696A Low-Frequency Inactivating <i>AKT2</i> Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.Diabetes2017
28975356Erratum to: A multi-stage genome-wide association study of uterine fibroids in African Americans.Hum Genet2017
28836065A multi-stage genome-wide association study of uterine fibroids in African Americans.Hum Genet2017
28436984Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk.Nat Genet2017
27835642Survey of the Heritability and Sparse Architecture of Gene Expression Traits across Human Tissues.PLoS Genet2016
27040689Imputing Gene Expression in Uncollected Tissues Within and Beyond GTEx.Am J Hum Genet2016
27398621The genetic architecture of type 2 diabetes.Nature2016
26574927C. elegans and mutants with chronic nicotine exposure as a novel model of cancer phenotype.Cancer Biology and Therapy2016
26258848A gene-based association method for mapping traits using reference transcriptome data.Nat Genet2015
25625282Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus.PLoS Genet2015
25724890MicroRNA biogenesis and cellular proliferation.Transl Res2015
24739237Integrative analyses of genetic variation, epigenetic regulation, and the transcriptome to elucidate the biology of platinum sensitivity.BMC Genomics2014
24504655Association of body mass index and outcomes after major lung resection.European Journal of Cardio-thoracic Surgery2014
25221879Genome-wide interrogation of longitudinal FEV1 in children with asthma.Am J Respir Crit Care Med2014
24549002Integrating cell-based and clinical genome-wide studies to identify genetic variants contributing to treatment failure in neuroblastoma patients.Clin Pharmacol Ther2014
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The University of Manchester
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Broad Institute of MIT and Harvard
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King's College London
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