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Author Details

Beverly A Mock
Center for Cancer Research, National Cancer Institute
1985
123
39
PMIDPaper TitleJournal TitlePublished Year
36883564mTOR inhibition overcomes RSK3-mediated resistance to BET inhibitors in small cell lung cancer.JCI Insight2023
37029320Use of CRISPR-based screens to identify mechanisms of chemotherapy resistance.Cancer Gene Ther2023
37356470Drug combinations identified by high-throughput screening promote cell cycle transition and upregulate Smad pathways in myeloma.Cancer Lett2023
36926457Structural Optimization and Anticancer Activity of Polo-like Kinase 1 (Plk1) Polo-Box Domain (PBD) Inhibitors and Their Prodrugs.ACS Pharmacol Transl Sci2023
34964999Conditional deletion of mTOR discloses its essential role in early B-cell development.Mol Carcinog2022
36369285Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice.Nat Commun2022
33950553Fatty acid oxidation is required for embryonic stem cell survival during metabolic stress.EMBO Rep2021
34876184WDR26 and MTF2 are therapeutic targets in multiple myeloma.J Hematol Oncol2021
32923678Mouse tumor susceptibility genes identify drug combinations for multiple myeloma.J Cancer Metastasis Treat2020
31898340Attenuation of immune-mediated bone marrow damage in conventionally housed mice.Mol Carcinog2020
33066043A Small Molecule Stabilizer of the MYC G4-Quadruplex Induces Endoplasmic Reticulum Stress, Senescence and Pyroptosis in Multiple Myeloma.Cancers (Basel)2020
32747423Hypomorphic mTOR Downregulates CDK6 and Delays Thymic Pre-T LBL Tumorigenesis.Mol Cancer Ther2020
32858886Conventional Co-Housing Modulates Murine Gut Microbiota and Hematopoietic Gene Expression.Int J Mol Sci2020
31061501The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcription.Nat Commun2019
31548308The transcription factor MZF1 differentially regulates murine <i>Mtor</i> promoter variants linked to tumor susceptibility.J Biol Chem2019
29255086The Reign of Antibodies: A Celebration of and Tribute to Michael Potter and His Homogeneous Immunoglobulin Workshops.J Immunol2018
30315240Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex.Nat Commun2018
29481610Characterization of clinically used oral antiseptics as quadruplex-binding ligands.Nucleic Acids Res2018
28522584Cooperative Targets of Combined mTOR/HDAC Inhibition Promote MYC Degradation.Mol Cancer Ther2017
29133782mTOR intersects antibody-inducing signals from TACI in marginal zone B cells.Nat Commun2017
28552607cFOS-SOX9 Axis Reprograms Bone Marrow-Derived Mesenchymal Stem Cells into Chondroblastic Osteosarcoma.Stem Cell Reports2017
26607598Molecular Pathways: Increased Susceptibility to Infection Is a Complication of mTOR Inhibitor Use in Cancer Therapy.Clin Cancer Res2016
26462961Small Molecule Microarrays Enable the Identification of a Selective, Quadruplex-Binding Inhibitor of MYC Expression.ACS Chem Biol2016
24429254TORC1 and class I HDAC inhibitors synergize to suppress mature B cell neoplasms.Mol Oncol2014
25193464Loss-of-function RNAi screens in breast cancer cells identify AURKB, PLK1, PIK3R1, MAPK12, PRKD2, and PTK6 as sensitizing targets of rapamycin activity.Cancer Lett2014
23357051A novel KIT-deficient mouse mast cell model for the examination of human KIT-mediated activation responses.J Immunol Methods2013
23858034B cell-specific deficiencies in mTOR limit humoral immune responses.J Immunol2013
23994476Increased mammalian lifespan and a segmental and tissue-specific slowing of aging after genetic reduction of mTOR expression.Cell Rep2013
22358507Mouse genetics 2011: meeting report.Mamm Genome2012
21252912CASZ1, a candidate tumor-suppressor gene, suppresses neuroblastoma tumor growth through reprogramming gene expression.Cell Death Differ2011
22053105mTORC1 and mTORC2 differentially regulate homeostasis of neoplastic and non-neoplastic human mast cells.Blood2011
21079150Constitutive reductions in mTOR alter cell size, immune cell development, and antibody production.Blood2011
19654412Mndal, a new interferon-inducible family member, is highly polymorphic, suppresses cell growth, and may modify plasmacytoma susceptibility.Blood2009
15514660The Collaborative Cross, a community resource for the genetic analysis of complex traits.Nat Genet2004
12700664p16 INK4a gene promoter variation and differential binding of a repressor, the ras-responsive zinc-finger transcription factor, RREB.Oncogene2003
14634638The nature and identification of quantitative trait loci: a community's view.Nat Rev Genet2003
14634209Frap, FKBP12 rapamycin-associated protein, is a candidate gene for the plasmacytoma resistance locus Pctr2 and can act as a tumor suppressor gene.Proc Natl Acad Sci U S A2003
11113205Efficiency alleles of the Pctr1 modifier locus for plasmacytoma susceptibility.Mol Cell Biol2001
10708524Structure and localization of mouse Pmscl1 and Pmscl2 genes.Genomics2000
10663557Mapping of the SWAP70 gene to mouse chromosome 7 and human chromosome 11p15.Immunogenetics2000
10501946Mouse chromosome 4.Mamm Genome1999
10396076The role of p16INK4a (Cdkn2a) in mouse plasma cell tumors.Curr Top Microbiol Immunol1999
9667751Multigenic control of skin tumor susceptibility in SENCARA/Pt mice.Carcinogenesis1998
9482902Cdkn2a, the cyclin-dependent kinase inhibitor encoding p16INK4a and p19ARF, is a candidate for the plasmacytoma susceptibility locus, Pctr1.Proc Natl Acad Sci U S A1998
9662621Encyclopedia of the mouse genome VII. Mouse chromosome 4.Mamm Genome1998
9524251Gene organization and chromosome location of the neural-specific RNA binding protein Elavl4.Gene1998
9354679The plasmacytoma resistance gene, Pctr2, delays the onset of tumorigenesis and resides in the telomeric region of chromosome 4.Blood1997
9209355MuLV-insertional mutagenesis of c-myb and Mml1 in a murine model for promonocytic leukemia.Leukemia1997
9233387Mouse chromosome 4.Mamm Genome1997
9328445New strains of inbred SENCAR mice with increased susceptibility to induction of papillomas and squamous cell carcinomas in skin.Mol Carcinog1997
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Collaborators

School of Public Health, Guizhou Medical University
Co-authored papers 25
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Co-authored papers 19
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Center for Cancer Research, National Cancer Institute
Co-authored papers 7
Centers for Disease Control and Prevention
Co-authored papers 5
University of California davis
Co-authored papers 5
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Co-authored papers 4
National Cancer Institute, National Institutes of Health
Co-authored papers 3
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Co-authored papers 3
and Blood Institute, National Institutes of Health
Co-authored papers 3
McMaster University & St. Joseph's Healthcare Hamilton
Co-authored papers 2
University of Essex
Co-authored papers 2
Mayo Clinic
Co-authored papers 2
Tufts University
Co-authored papers 2
Co-authored papers 2
Oregon Health & Science University
Co-authored papers 2
Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham
Co-authored papers 2
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College Station
Co-authored papers 2
National Heart Lung and Blood Institute Division of Intramural Research
Co-authored papers 2
University of Virginia
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Louisiana State University
Co-authored papers 2
Portland Alcohol Research Center, Oregon Health and Science University
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Wellcome Trust Sanger Institute
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National Center for Advancing Translational Sciences
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and Blood Institute, National Institutes of Health
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Portland Alcohol Research Center, Oregon Health & Science University
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