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Author Details

Forest M White
Massachusetts Institute of Technology
1995
149
49
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36841147Antigen discovery for the development of cancer immunotherapy.Semin Immunol2023
37717406Actuated tissue engineered muscle grafts restore functional mobility after volumetric muscle loss.Biomaterials2023
38015076Phosphoproteomic Changes Induced by Cell-Derived Matrix and Their Effect on Tumor Cell Migration and Cytoskeleton Remodeling.ACS Biomater Sci Eng2023
37961516Dissecting signaling regulators driving AXL-mediated bypass resistance and associated phenotypes by phosphosite perturbations.bioRxiv2023
37323574Decrypting the potency of anti-cancer therapeutics by using mass spectrometry to quantify post-translational modifications.Cell Rep Methods2023
37073954Immunopeptidomics reveals determinants of Mycobacterium tuberculosis antigen presentation on MHC class I.Elife2023
37169593Predictive data-driven modeling of C-terminal tyrosine function in the EGFR signaling network.Life Sci Alliance2023
34383057Multimodal platform for assessing drug distribution and response in clinical trials.Neuro Oncol2022
35843356RNA-binding protein ELAVL4/HuD ameliorates Alzheimer's disease-related molecular changes in human iPSC-derived neurons.Prog Neurobiol2022
35705813Deciphering the immunopeptidome in vivo reveals new tumour antigens.Nature2022
36454758MEK inhibition enhances presentation of targetable MHC-I tumor antigens in mutant melanomas.Proc Natl Acad Sci U S A2022
36077757Identification of Src Family Kinases as Potential Therapeutic Targets for Chemotherapy-Resistant Triple Negative Breast Cancer.Cancers (Basel)2022
34050676Heterogeneous delivery across the blood-brain barrier limits the efficacy of an EGFR-targeting antibody drug conjugate in glioblastoma.Neuro Oncol2021
357569721,2,3, MHC: a review of mass-spectrometry-based immunopeptidomics methods for relative and absolute quantification of pMHCs.Immunooncol Technol2021
37117831Quantitative phosphoproteomics uncovers dysregulated kinase networks in Alzheimer's disease.Nat Aging2021
33509940High-Density, Targeted Monitoring of Tyrosine Phosphorylation Reveals Activated Signaling Networks in Human Tumors.Cancer Res2021
33730582Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice.Cell Rep2021
34589640Global Cancer Risk From Unregulated Polycyclic Aromatic Hydrocarbons.Geohealth2021
34497125Absolute quantification of tumor antigens using embedded MHC-I isotopologue calibrants.Proc Natl Acad Sci U S A2021
34468274Phosphoproteomics: a valuable tool for uncovering molecular signaling in cancer cells.Expert Rev Proteomics2021
34545087Peak learning of mass spectrometry imaging data using artificial neural networks.Nat Commun2021
34016623Quantitative Analysis of Tyrosine Phosphorylation from FFPE Tissues Reveals Patient-Specific Signaling Networks.Cancer Res2021
34342538Leveraging Immunopeptidomics To Study and Combat Infectious Disease.mSystems2021
34052394Quantitative Consequences of Protein Carriers in Immunopeptidomics and Tyrosine Phosphorylation MS<sup>2</sup> Analyses.Mol Cell Proteomics2021
32488085Multiplexed relative and absolute quantitative immunopeptidomics reveals MHC I repertoire alterations induced by CDK4/6 inhibition.Nat Commun2020
31767628Localized Metabolomic Gradients in Patient-Derived Xenograft Models of Glioblastoma.Cancer Res2020
33289969Phosphoproteomics identifies microglial Siglec-F inflammatory response during neurodegeneration.Mol Syst Biol2020
32978160Platform for micro-invasive membrane-free biochemical sampling of brain interstitial fluid.Sci Adv2020
32965214Light-regulated allosteric switch enables temporal and subcellular control of enzyme activity.Elife2020
30670633Systemic analysis of tyrosine kinase signaling reveals a common adaptive response program in a HER2-positive breast cancer.Sci Signal2019
31213460Rebalancing Protein Homeostasis Enhances Tumor Antigen Presentation.Clin Cancer Res2019
31464373High-fat diet in a mouse insulin-resistant model induces widespread rewiring of the phosphotyrosine signaling network.Mol Syst Biol2019
30676316Exploration of CTCF post-translation modifications uncovers Serine-224 phosphorylation by PLK1 at pericentric regions during the G2/M transition.Elife2019
29162725Src homology 2 domains enhance tyrosine phosphorylation <i>in vivo</i> by protecting binding sites in their target proteins from dephosphorylation.J Biol Chem2018
30464169Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma.Nat Commun2018
30485822Microtubule-Based Control of Motor-Clutch System Mechanics in Glioma Cell Migration.Cell Rep2018
30466063A Proteomics Approach to Profiling the Temporal Translational Response to Stress and Growth.iScience2018
29443976How many human proteoforms are there?Nat Chem Biol2018
29203461Identifying and Targeting Sporadic Oncogenic Genetic Aberrations in Mouse Models of Triple-Negative Breast Cancer.Cancer Discov2018
29344889Quantitative Analysis of Tyrosine Kinase Signaling Across Differentially Embedded Human Glioblastoma Tumors.Methods Mol Biol2018
28830985Characterization of <i>In Vivo</i> Resistance to Osimertinib and JNJ-61186372, an EGFR/Met Bispecific Antibody, Reveals Unique and Consensus Mechanisms of Resistance.Mol Cancer Ther2017
28415827Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway.Oncotarget2017
28371736On-demand dissolution of modular, synthetic extracellular matrix reveals local epithelial-stromal communication networks.Biomaterials2017
29241556Hepatic Dysfunction Caused by Consumption of a High-Fat Diet.Cell Rep2017
27049636Methods for the Analysis of Protein Phosphorylation-Mediated Cellular Signaling Networks.Annu Rev Anal Chem (Palo Alto Calif)2016
26584919Identification of Direct Kinase Substrates Using Analogue-Sensitive Alleles.Methods Mol Biol2016
27479327Revealing disease-associated pathways by network integration of untargeted metabolomics.Nat Methods2016
27354287Network Modeling Identifies Patient-specific Pathways in Glioblastoma.Sci Rep2016
27196784Quantitative Phosphoproteomics Reveals Wee1 Kinase as a Therapeutic Target in a Model of Proneural Glioblastoma.Mol Cancer Ther2016
27071344Time-resolved multimodal analysis of Src Homology 2 (SH2) domain binding in signaling by receptor tyrosine kinases.Elife2016
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Collaborators

Douglas A Lauffenburger
Massachusetts Institute of Technology
Co-authored papers 19
Donald F Hunt
University of Virginia
Co-authored papers 15
Jeffrey Shabanowitz
University of Virginia
Co-authored papers 13
Jann N Sarkaria
Co-authored papers 11
Bryan D Bryson
Massachusetts Institute of Technology, USA The Ragon Institute of MGH
Co-authored papers 10
Victor H Engelhard
University of Virginia School of Medicine
Co-authored papers 8
Alejandro Wolf-Yadlin
University of Washington
Co-authored papers 6
Nathalie Y R Agar
Co-authored papers 5
Jeffrey N Agar
Northeastern University
Co-authored papers 5
Frank B Furnari
University of California San Diego
Co-authored papers 4
Chance John Luckey
University of Virginia School of Medicine.
Co-authored papers 4
Ernest Fraenkel
Co-authored papers 4
Michael S Regan
Co-authored papers 4
Alan Saghatelian
Salk Institute for Biological Studies
Co-authored papers 3
Sandro Santagata
Co-authored papers 3
Webster K Cavenee
Ludwig Institute for Cancer Research, University of California San Diego
Co-authored papers 3
Leona D Samson
Massachusetts Institute of Technology
Co-authored papers 2
Henry Rodriguez
Office of Cancer Clinical Proteomics Research, National Cancer Institute
Co-authored papers 2
Ryan A Flynn
Boston Children's Hospital
Co-authored papers 2
Ayla Ergun
Harvard Medical School
Co-authored papers 2
Pamela Milani
Co-authored papers 2
Judy C Boughey
Mayo Clinic
Co-authored papers 2
Daniel C Liebler
Co-authored papers 2
Douglas A Levine
Perlmutter Cancer Center
Co-authored papers 2
Matthew P Goetz
Mayo Clinic
Co-authored papers 2
Liewei Wang
Mayo Clinic
Co-authored papers 2
Tyler Jacks
Co-authored papers 2
Giorgio Gaglia
Co-authored papers 2
Christopher L Hendrickson
Florida State University
Co-authored papers 2
Patrick Y Wen
Co-authored papers 2
Release 1.2