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Author Details

Philip O Scumpia
David Geffen School of Medicine, University of California Los Angeles
2002
80
35
PMIDPaper TitleJournal TitlePublished Year
36123029Engineering Immunomodulatory Biomaterials to Drive Skin Wounds toward Regenerative Healing.Cold Spring Harb Perspect Biol2023
37592104Ipilimumab with or without nivolumab in PD-1 or PD-L1 blockade refractory metastatic melanoma: a randomized phase 2 trial.Nat Med2023
37750461Improved Humoral Immunity and Protection against Influenza Virus Infection with a 3d Porous Biomaterial Vaccine.Adv Sci (Weinh)2023
37985462Injectable Microporous Annealed Crescent-Shaped (MAC) Particle Hydrogel Scaffold for Enhanced Cell Infiltration.Adv Healthc Mater2023
37106167Multi-organ landscape of therapy-resistant melanoma.Nat Med2023
36823180De novo tissue formation using custom microporous annealed particle hydrogel provides long-term vocal fold augmentation.NPJ Regen Med2023
36333379Parkin regulates adiposity by coordinating mitophagy with mitochondrial biogenesis in white adipocytes.Nat Commun2022
33318037Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity.Cancer Discov2021
33784499Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication.Cell Rep2021
33914706Melanoma dedifferentiation induced by IFN-γ epigenetic remodeling in response to anti-PD-1 therapy.J Clin Invest2021
34795202Biopsy-free in vivo virtual histology of skin using deep learning.Light Sci Appl2021
34161353Wound healing with topical BRAF inhibitor therapy in a diabetic model suggests tissue regenerative effects.PLoS One2021
34036652Detection of viral gene expression in risk-stratified biopsies reveals no active HPV in cutaneous squamous cell carcinoma.Exp Dermatol2021
33168979Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing.Nat Mater2021
32514064Interferon-mediated reprogramming of membrane cholesterol to evade bacterial toxins.Nat Immunol2020
32080181Collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice.Nat Commun2020
32339990ER Stress Regulates Immunosuppressive Function of Myeloid Derived Suppressor Cells in Leprosy that Can Be Overcome in the Presence of IFN-γ.iScience2020
32516576Toll-Like Receptors Induce Signal-Specific Reprogramming of the Macrophage Lipidome.Cell Metab2020
31410986Enhanced In Vivo Delivery of Stem Cells using Microporous Annealed Particle Scaffolds.Small2019
29436012Skin lesions serve as clues to relapse of pediatric blastic plasmacytoid dendritic cell neoplasm.Pediatr Dermatol2018
31015734Publisher Correction: Elastomeric sensor surfaces for high-throughput single-cell force cytometry.Nat Biomed Eng2018
31015629Elastomeric sensor surfaces for high-throughput single-cell force cytometry.Nat Biomed Eng2018
29610140<i>Mycobacterium tuberculosis</i> Transfer RNA Induces IL-12p70 via Synergistic Activation of Pattern Recognition Receptors within a Cell Network.J Immunol2018
28841420A Macrophage Response to Mycobacterium leprae Phenolic Glycolipid Initiates Nerve Damage in Leprosy.Cell2017
29033353Melanocyte Stem Cell Activation and Translocation Initiate Cutaneous Melanoma in Response to UV Exposure.Cell Stem Cell2017
29136063Levofloxacin-induced purpura annularis telangiectodes of Majocchi.Cutis2017
28704551Opposing roles of Toll-like receptor and cytosolic DNA-STING signaling pathways for Staphylococcus aureus cutaneous host defense.PLoS Pathog2017
28930658Defined Sensing Mechanisms and Signaling Pathways Contribute to the Global Inflammatory Gene Expression Output Elicited by Ionizing Radiation.Immunity2017
28864476Recurrent Tumor Cell-Intrinsic and -Extrinsic Alterations during MAPKi-Induced Melanoma Regression and Early Adaptation.Cancer Discov2017
27095696Tumor suppressor identity can contribute to heterogeneity of phenotype in hair follicle stem cell-induced squamous cell carcinoma.Exp Dermatol2016
26556220Use of Becaplermin for nondiabetic ulcers: pyoderma gangrenosum and calciphylaxis.Dermatol Ther2016
27114524Targeting IL-17A attenuates neonatal sepsis mortality induced by IL-18.Proc Natl Acad Sci U S A2016
25111617Comparison of molecular signatures from multiple skin diseases identifies mechanisms of immunopathogenesis.J Invest Dermatol2015
26509037Systematic evaluation of natural scaffolds in cutaneous wound healing.J Mater Chem B2015
26101326Neonatal CD71+ Erythroid Cells Do Not Modify Murine Sepsis Mortality.J Immunol2015
26057515Papules on the face and body.Cutis2015
26030305Accelerated wound healing by injectable microporous gel scaffolds assembled from annealed building blocks.Nat Mater2015
25548220TRIF-dependent innate immune activation is critical for survival to neonatal gram-negative sepsis.J Immunol2015
24269587Alpha-lipoic acid effects on brain glial functions accompanying double-stranded RNA antiviral and inflammatory signaling.Neurochem Int2014
24829407Novel role for tumor-induced expansion of myeloid-derived cells in cancer cachexia.J Immunol2014
24335650Stem cell quiescence acts as a tumour suppressor in squamous tumours.Nat Cell Biol2014
23509349Maintenance of anti-Sm/RNP autoantibody production by plasma cells residing in ectopic lymphoid tissue and bone marrow memory B cells.J Immunol2013
21106855Sepsis induces early alterations in innate immunity that impact mortality to secondary infection.J Immunol2011
21518789Critical role for CXC ligand 10/CXC receptor 3 signaling in the murine neonatal response to sepsis.Infect Immun2011
21746813B cells enhance early innate immune responses during bacterial sepsis.J Exp Med2011
21690321Neutrophil mobilization from the bone marrow during polymicrobial sepsis is dependent on CXCL12 signaling.J Immunol2011
21085745A paradoxical role for myeloid-derived suppressor cells in sepsis and trauma.Mol Med2011
20071504Type I interferon signaling in hematopoietic cells is required for survival in mouse polymicrobial sepsis by regulating CXCL10.J Exp Med2010
20130216Cutting edge: bacterial infection induces hematopoietic stem and progenitor cell expansion in the absence of TLR signaling.J Immunol2010
19387804Major hepatectomy induces phenotypic changes in circulating dendritic cells and monocytes.J Clin Immunol2009
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Collaborators

University of Florida College of Medicine.
Co-authored papers 31
David Geffen School of Medicine, University of California Los Angeles
Co-authored papers 25
University of Florida Health
Co-authored papers 17
University of Michigan ann arbor
Co-authored papers 15
University of Florida, College of Medicine
Co-authored papers 11
University of Florida College of Medicine
Co-authored papers 9
Boston Children's Hospital
Co-authored papers 9
University of Florida
Co-authored papers 8
Co-authored papers 7
Merck & Co. Inc.
Co-authored papers 7
University of Florida College of Medicine
Co-authored papers 7
The University of Kansas Health System
Co-authored papers 6
Co-authored papers 6
Co-authored papers 5
University of California Los Angeles (university of california los angeles)
Co-authored papers 5
University of Occupational and Environmental Health
Co-authored papers 4
Co-authored papers 4
Co-authored papers 3
Co-authored papers 2
College of Chemistry and Materials Science, Northwest University
Co-authored papers 2
University of Florida
Co-authored papers 2
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Co-authored papers 2
Beth Israel Deaconess Hospital
Co-authored papers 2
University of Florida College of Medicine
Co-authored papers 2
University of Florida College of Medicine and Dentistry
Co-authored papers 2
National Defense Medical College
Co-authored papers 2
University of Florida Central Florida USA.
Co-authored papers 2
Brown University
Co-authored papers 2
College of Medicine, University of Florida
Co-authored papers 2