Skip to Main Content

Author Details

Aled M Edwards
University of Toronto
1984
221
66
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37360399Target 2035 - an update on private sector contributions.RSC Med Chem2023
35271333Stopping pandemics before they start: Lessons learned from SARS-CoV-2.Science2022
35783295CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-finding.Nat Rev Chem2022
36447653An open source plant kinase chemogenomics set.Plant Direct2022
34029586Cancer blues? A promising judgment bias task indicates pessimism in nude mice with tumors.Physiol Behav2021
35211674Target 2035 - update on the quest for a probe for every protein.RSC Med Chem2021
34326222No shortcuts to SARS-CoV-2 antivirals.Science2021
34246180Opinion: Independent third-party entities as a model for validation of commercial antibodies.N Biotechnol2021
32369358Targeting ALK2: An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma.J Med Chem2020
32914973What Are the Odds of Finding a COVID-19 Drug from a Lab Repurposing Screen?J Chem Inf Model2020
32265506The RESOLUTE consortium: unlocking SLC transporters for drug discovery.Nat Rev Drug Discov2020
31612854Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72.Elife2019
29676732Donated chemical probes for open science.Elife2018
30705971Ideation and implementation of an open science drug discovery business model - M4K Pharma.Wellcome Open Res2018
28566431A trust approach for sharing research reagents.Sci Transl Med2017
28162900Discovery and structure activity relationship of the first potent cryptosporidium FIKK kinase inhibitor.Bioorg Med Chem2017
26983524Reproducibility: Team up with industry.Nature2016
27595404A proposal for validation of antibodies.Nat Methods2016
27167397Perspective: Science is still too closed.Nature2016
25722227Preclinical target validation using patient-derived cells.Nat Rev Drug Discov2015
26437229Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins.PLoS One2015
26485080Corrigendum: The promise and peril of chemical probes.Nat Chem Biol2015
26232220A Call for Systematic Research on Solute Carriers.Cell2015
26071590Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases from Saccharomyces cerevisiae: BIOCHEMICAL, STRUCTURAL, AND EVOLUTIONARY INSIGHTS.J Biol Chem2015
26121405Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation.Nat Methods2015
26112892Biochemical characterization of FIKK8--A unique protein kinase from the malaria parasite Plasmodium falciparum and other apicomplexans.Mol Biochem Parasitol2015
24590706Structural genomics of human proteins.Methods Mol Biol2014
25306867Structural characterization of the putative ABC-type 2 transporter from Thermotoga maritima MSB8.J Struct Funct Genomics2014
24596128Highlights of B/D-HPP and HPP Resource Pillar Workshops at 12th Annual HUPO World Congress of Proteomics: September 14-18, 2013, Yokohama, Japan.Proteomics2014
23322723Structural insights into aldosterone synthase substrate specificity and targeted inhibition.Mol Endocrinol2013
24097944Structural and functional studies of gpX of Escherichia coli phage P2 reveal a widespread role for LysM domains in the baseplates of contractile-tailed phages.J Bacteriol2013
24086123Ten simple rules for cultivating open science and collaborative R&D.PLoS Comput Biol2013
23716676Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states.Proc Natl Acad Sci U S A2013
23542344A conserved spiral structure for highly diverged phage tail assembly chaperones.J Mol Biol2013
23542343Tail tip proteins related to bacteriophage λ gpL coordinate an iron-sulfur cluster.J Mol Biol2013
23539603The structural basis of ZMPSTE24-dependent laminopathies.Science2013
23238671A public-private partnership to unlock the untargeted kinome.Nat Chem Biol2013
23259511The biology/disease-driven human proteome project (B/D-HPP): enabling protein research for the life sciences community.J Proteome Res2013
22284390Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members.FEBS J2012
22704758A generalizable pre-clinical research approach for orphan disease therapy.Orphanet J Rare Dis2012
22801427Structural and biochemical characterization of phage λ FI protein (gpFI) reveals a novel mechanism of DNA packaging chaperone activity.J Biol Chem2012
22797755The bacteriophage HK97 gp15 moron element encodes a novel superinfection exclusion protein.J Bacteriol2012
21219465A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair.Mol Microbiol2011
21601576Structural analysis of a putative aminoglycoside N-acetyltransferase from Bacillus anthracis.J Mol Biol2011
21625866Crystal structure of a putative transcriptional regulator SCO0520 from Streptomyces coelicolor A3(2) reveals an unusual dimer among TetR family proteins.J Struct Funct Genomics2011
21743462A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells.Nat Chem Biol2011
21697527Leveraging crowdsourcing to facilitate the discovery of new medicines.Sci Transl Med2011
21362626Structure and biochemical functions of SIRT6.J Biol Chem2011
21307913Too many roads not taken.Nature2011
21451121The precompetitive space: time to move the yardsticks.Sci Transl Med2011
  • 1 - 50 of 221

Recommended Authors

Thomas Clayton
Celgene/Bristol-Myers Squibb Corporation
Career Start Year 2004
Number of shared co-authors 7
Lester G Carter
Stanford University
Career Start Year 2004
Number of shared co-authors 14
Heath E Klock
Merck & Co., Inc.
Career Start Year 2002
Number of shared co-authors 8
Marc C Deller
Incyte Corporation
Career Start Year 2000
Number of shared co-authors 5
Andrew P VanDemark
University of Pittsburgh
Career Start Year 2000
Number of shared co-authors 0
Sergey M Vorobiev
Columbia University
Career Start Year 1998
Number of shared co-authors 17
Cameron Mura
University of Virginia
Career Start Year 1998
Number of shared co-authors 1
Chad A Brautigam
UT Southwestern Medical Center
Career Start Year 1997
Number of shared co-authors 1
Piotr Sliz
The Manton Center for Orphan Disease Research, Boston Children's Hospital
Career Start Year 1996
Number of shared co-authors 4
Ashley M Deacon
Accelero Biostructures Inc., USA XPose Therapeutics Inc.
Career Start Year 1996
Number of shared co-authors 7
Andreas Bracher
Max-Planck-Institute of Biochemistry
Career Start Year 1995
Number of shared co-authors 2
Clemens Vonrhein
Global Phasing Ltd
Career Start Year 1995
Number of shared co-authors 2
Diana R Tomchick
University of Texas Southwestern Medical Center
Career Start Year 1993
Number of shared co-authors 2
Gyorgy Babnigg
Argonne National Laboratory
Career Start Year 1992
Number of shared co-authors 10
Gye Won Han
Bridge Institute, University of Southern California
Career Start Year 1991
Number of shared co-authors 10
Marc-Andr?? Elsliger
Joint Center for Structural Genomics
Career Start Year 1989
Number of shared co-authors 7
Mark W Knuth
Joint Center for Structural Genomics
Career Start Year 1988
Number of shared co-authors 8
Christopher W V Hogue
National University of Singapore
Career Start Year 1987
Number of shared co-authors 5
Donald D Lorimer
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Career Start Year 1986
Number of shared co-authors 13
Mamoru Sato
Yokohama City University
Career Start Year 1982
Number of shared co-authors 1
Chris Sander
Broad Institute of MIT and Harvard
Career Start Year 1979
Number of shared co-authors 21
David T Jones
University College London
Career Start Year 1977
Number of shared co-authors 8
Ivan Rayment
College of Agricultural and Life Sciences, University of Wisconsin-Madison
Career Start Year 1976
Number of shared co-authors 1
Gianni Cesareni
University of Rome 'Tor Vergata'
Career Start Year 1976
Number of shared co-authors 9
Tom Alber
University of California berkeley
Career Start Year 1976
Number of shared co-authors 7
George N Phillips
Rice University
Career Start Year 1974
Number of shared co-authors 10
Tom L Blundell
Heartand Lung Research Institute, University of Cambridge
Career Start Year 1971
Number of shared co-authors 6
Wayne A Hendrickson
Columbia University
Career Start Year 1968
Number of shared co-authors 11
Robert M Stroud
University of California San Francisco
Career Start Year 1965
Number of shared co-authors 7
David Eisenberg
university of california los angeles
Career Start Year 1963
Number of shared co-authors 12

Collaborators

Cheryl H Arrowsmith
University of Toronto
Co-authored papers 72
Alexei Savchenko
University of Toronto
Co-authored papers 51
Andrzej Joachimiak
Center for Structural Biology of Infectious Diseases, University of Chicago
Co-authored papers 34
Adelinda Yee
University of Toronto
Co-authored papers 20
Elena Evdokimova
University of Toronto
Co-authored papers 18
Alexey Bochkarev
University of Toronto
Co-authored papers 17
Michael A Kennedy
Miami University
Co-authored papers 12
John R Cort
Pacific Northwest National Laboratory
Co-authored papers 12
Maksymilian Chruszcz
University of South Carolina, Michigan State University
Co-authored papers 11
Wladek Minor
University of Virginia
Co-authored papers 11
Roger D Kornberg
Stanford University
Co-authored papers 10
Mark Gerstein
Yale University
Co-authored papers 9
Alan R Davidson
University of Toronto, University Avenue
Co-authored papers 9
Seth A Darst
The Rockefeller University
Co-authored papers 8
Youngchang Kim
Argonne National Laboratory
Co-authored papers 8
Walter J Chazin
and Center for Structural Biology, Vanderbilt University
Co-authored papers 7
Stefan Knapp
Institute of Pharmaceutical Chemistry, Goethe University
Co-authored papers 7
Raymond Hui
University of Toronto
Co-authored papers 7
Donald E Awrey
The Campbell Family Institute for Breast Cancer Research, College Street
Co-authored papers 7
Jack F Greenblatt
College Street, University of Toronto
Co-authored papers 7
James E Bray
University of Oxford
Co-authored papers 5
Antonio Pineda-Lucena
Instituto de Investigacion Sanitaria La Fe
Co-authored papers 5
Hee-Won Park
Kangwon National University College of Medicine
Co-authored papers 4
Susanne Gr??slund
Karolinska Institutet
Co-authored papers 4
Liang Tong
Columbia University
Co-authored papers 4
James D Watson
EMBL--European Bioinformatics Institute
Co-authored papers 4
Suzanne Ackloo
University of Toronto
Co-authored papers 4
Bart Kus
Hospital for Sick Children, University of Toronto
Co-authored papers 4
Yuval Kluger
Yale University School of Medicine
Co-authored papers 3
Ruedi Aebersold
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 3
Release 1.2