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Author Details

David M Reif
Bioinformatics Research Center, North Carolina State University
2004
129
45
PMIDPaper TitleJournal TitlePublished Year
36370075TCDD alters essential transcriptional regulators of osteogenic differentiation in multipotent mesenchymal stem cells.Toxicol Sci2023
37579019Aggregated Molecular Phenotype Scores: Enhancing Assessment and Visualization of Mass Spectrometry Imaging Data for Tissue-Based Diagnostics.Anal Chem2023
37242540<i>MKX-AS1</i> Gene Expression Associated with Variation in Drug Response to Oxaliplatin and Clinical Outcomes in Colorectal Cancer Patients.Pharmaceuticals (Basel)2023
37242509<i>RYK</i> Gene Expression Associated with Drug Response Variation of Temozolomide and Clinical Outcomes in Glioma Patients.Pharmaceuticals (Basel)2023
37371044Pharmacogenomic Analyses Implicate B Cell Developmental Status and <i>MKL1</i> as Determinants of Sensitivity toward Anti-CD20 Monoclonal Antibody Therapy.Cells2023
37333214Utilizing Aggregated Molecular Phenotype (AMP) Scores to Visualize Simultaneous Molecular Changes in Mass Spectrometry Imaging Data.bioRxiv2023
37197290Bayesian matrix completion for hypothesis testing.J R Stat Soc Ser C Appl Stat2023
36788734Legacy and emerging per- and polyfluoroalkyl substances suppress the neutrophil respiratory burst.J Immunotoxicol2023
35168583Demonstrating a systems approach for integrating disparate data streams to inform decisions on children's environmental health.BMC Public Health2022
35474345ToxPi*GIS Toolkit: creating, viewing, and sharing integrative visualizations for geospatial data using ArcGIS.J Expo Sci Environ Epidemiol2022
35377459The Ahr2-Dependent wfikkn1 Gene Influences Zebrafish Transcriptome, Proteome, and Behavior.Toxicol Sci2022
35573279Leveraging a High-Throughput Screening Method to Identify Mechanisms of Individual Susceptibility Differences in a Genetically Diverse Zebrafish Model.Front Toxicol2022
35812168Development of the InTelligence And Machine LEarning (TAME) Toolkit for Introductory Data Science, Chemical-Biological Analyses, Predictive Modeling, and Database Mining for Environmental Health Research.Front Toxicol2022
35514159Comparison of National Vulnerability Indices Used by the Centers for Disease Control and Prevention for the COVID-19 Response.Public Health Rep2022
35387429Implementation of Zebrafish Ontologies for Toxicology Screening.Front Toxicol2022
36548602Utilizing a Population-Genetic Framework to Test for Gene-Environment Interactions between Zebrafish Behavior and Chemical Exposure.Toxics2022
35863239Wildfires and extracellular vesicles: Exosomal MicroRNAs as mediators of cross-tissue cardiopulmonary responses to biomass smoke.Environ Int2022
35263707Systematic developmental toxicity assessment of a structurally diverse library of PFAS in zebrafish.J Hazard Mater2022
33400596The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring County-Level Vulnerability Using Visualization, Statistical Modeling, and Machine Learning.Environ Health Perspect2021
33917455Uncovering Evidence for Endocrine-Disrupting Chemicals That Elicit Differential Susceptibility through Gene-Environment Interactions.Toxics2021
35295121Concurrent Evaluation of Mortality and Behavioral Responses: A Fast and Efficient Testing Approach for High-Throughput Chemical Hazard Identification.Front Toxicol2021
34824997Development of a Pandemic Awareness STEM Outreach Curriculum: Utilizing a Computational Thinking Taxonomy Framework.Educ Sci (Basel)2021
34437536High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs.PLoS Genet2021
34671776ToxPi*GIS Toolkit: Creating, viewing, and sharing integrative visualizations for geospatial data using ArcGIS.medRxiv2021
34044623Extending the lymphoblastoid cell line model for drug combination pharmacogenomics.Pharmacogenomics2021
34214078Leveraging high-throughput screening data, deep neural networks, and conditional generative adversarial networks to advance predictive toxicology.PLoS Comput Biol2021
34029068Multiomic Big Data Analysis Challenges: Increasing Confidence in the Interpretation of Artificial Intelligence Assessments.Anal Chem2021
31158294Inappropriate Citation of Vaccine Article.J Infect Dis2020
31730801Sex-specific effects of perinatal FireMaster® 550 (FM 550) exposure on socioemotional behavior in prairie voles.Neurotoxicol Teratol2020
32053902HGBEnviroScreen: Enabling Community Action through Data Integration in the Houston-Galveston-Brazoria Region.Int J Environ Res Public Health2020
31822930Concentration-response evaluation of ToxCast compounds for multivariate activity patterns of neural network function.Arch Toxicol2020
33187264Children's Environmental Health: A Systems Approach for Anticipating Impacts from Chemicals.Int J Environ Res Public Health2020
33094747Structural-based connectivity and omic phenotype evaluations (SCOPE): a cheminformatics toolbox for investigating lipidomic changes in complex systems.Analyst2020
32827657The multi-dimensional embryonic zebrafish platform predicts flame retardant bioactivity.Reprod Toxicol2020
32817964The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring county-level vulnerability using visualization, statistical modeling, and machine learning.medRxiv2020
32407153<i>In vivo</i> assessment of respiratory burst inhibition by xenobiotic exposure using larval zebrafish.J Immunotoxicol2020
30938251Systematic determination of the relationship between nanoparticle core diameter and toxicity for a series of structurally analogous gold nanoparticles in zebrafish.Nanotoxicology2019
31681399Synergistic Chemotherapy Drug Response Is a Genetic Trait in Lymphoblastoid Cell Lines.Front Genet2019
32133425Multivariate modeling of engineered nanomaterial features associated with developmental toxicity.NanoImpact2019
31323264Determination of chemical-disease risk values to prioritize connections between environmental factors, genetic variants, and human diseases.Toxicol Appl Pharmacol2019
31453412Integration of curated and high-throughput screening data to elucidate environmental influences on disease pathways.Comput Toxicol2019
31425687Population-based toxicity screening in human induced pluripotent stem cell-derived cardiomyocytes.Toxicol Appl Pharmacol2019
30897121Associations between access to healthcare, environmental quality, and end-stage renal disease survival time: Proportional-hazards models of over 1,000,000 people over 14 years.PLoS One2019
28738424Use of high-throughput in vitro toxicity screening data in cancer hazard evaluations by IARC Monograph Working Groups.ALTEX2018
29891985Confirmation of high-throughput screening data and novel mechanistic insights into VDR-xenobiotic interactions by orthogonal assays.Sci Rep2018
29942350Characterizing the effects of missing data and evaluating imputation methods for chemical prioritization applications using ToxPi.BioData Min2018
29968567Elucidating Gene-by-Environment Interactions Associated with Differential Susceptibility to Chemical Exposure.Environ Health Perspect2018
30429298Neonatal mice exposed to a high-fat diet <i>in utero</i> influence the behaviour of their nursing dam.Proc Biol Sci2018
29506467ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models.BMC Bioinformatics2018
29368091Population genetic diversity in zebrafish lines.Mamm Genome2018
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Collaborators

Co-authored papers 32
Co-authored papers 26
National Institute of Environmental Health Sciences
Co-authored papers 21
Incyte Research Institute, Incyte Corporation
Co-authored papers 18
Bioinformatics Research Center, North Carolina State University
Co-authored papers 14
Cumming School of Medicine, University of Calgary
Co-authored papers 11
Cedars-Sinai Medical Center
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Center for Systems Genomics, Pennsylvania State University, University Park
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Center for Precision Medicine and Functional Genomics, Utah Tech University
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Vanderbilt University Medical Center
Co-authored papers 5
North Carolina State University, USA Center for Human Health and the Environment
Co-authored papers 4
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Center for Computational Toxicology and Exposure
Co-authored papers 4
North Carolina State University
Co-authored papers 4
Vanderbilt University Medical Center
Co-authored papers 3
St. George's University Medical School
Co-authored papers 3
Co-authored papers 3
National Center for Toxicological Research
Co-authored papers 2
Pacific Northwest National Laboratory
Co-authored papers 2
National Institute of Environmental Health Sciences
Co-authored papers 2
University of Konstanz
Co-authored papers 2
National Cancer Institute, National Institutes of Health
Co-authored papers 2
The University of Tulsa
Co-authored papers 2
North Carolina State University
Co-authored papers 2
Department of Mathematics and Computer Science Fisk University
Co-authored papers 2
University of North Carolina
Co-authored papers 2
Institut Pasteur, Universite Paris Cite
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