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Author Details

Luke M Rice
the University of Texas Southwestern Medical Center
1994
49
30
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37205370Interface-acting nucleotide controls polymerization dynamics at microtubule plus- and minus-ends.bioRxiv2023
36580070Working strokes produced by curling protofilaments at disassembling microtubule tips can be biochemically tuned and vary with species.Elife2022
33734292Microtubules form by progressively faster tubulin accretion, not by nucleation-elongation.J Cell Biol2021
32516593Nucleating a Microtubule: Put a γ-Tubulin Ring on It.Dev Cell2020
32077153Insights into allosteric control of microtubule dynamics from a buried β-tubulin mutation that causes faster growth and slower shrinkage.Protein Sci2020
33180487A Multipronged Approach Establishes Covalent Modification of β-Tubulin as the Mode of Action of Benzamide Anti-cancer Toxins.J Med Chem2020
32773040Cryo-EM structure of VASH1-SVBP bound to microtubules.Elife2020
32332092CLASPs at a glance.J Cell Sci2020
30943103Long-range, through-lattice coupling improves predictions of microtubule catastrophe.Mol Biol Cell2019
30019982ACTG2-Associated Visceral Myopathy With Chronic Intestinal Pseudoobstruction, Intestinal Malrotation, Hypertrophic Pyloric Stenosis, Choledochal Cyst, and a Novel Missense Mutation.Int J Surg Pathol2019
31584935Kinetochore-associated Stu2 promotes chromosome biorientation in vivo.PLoS Genet2019
30804205Direct observation of individual tubulin dimers binding to growing microtubules.Proc Natl Acad Sci U S A2019
29278985Structural and functional differences between porcine brain and budding yeast microtubules.Cell Cycle2018
30217954Proteins that control the geometry of microtubules at the ends of cilia.J Cell Biol2018
29851564An isolated CLASP TOG domain suppresses microtubule catastrophe and promotes rescue.Mol Biol Cell2018
29897335Design principles of a microtubule polymerase.Elife2018
30006463A new look for the growing microtubule end?J Cell Biol2018
29674711Microtubule dynamics: an interplay of biochemistry and mechanics.Nat Rev Mol Cell Biol2018
28652389Structural differences between yeast and mammalian microtubules revealed by cryo-EM.J Cell Biol2017
28628007Direct measurement of conformational strain energy in protofilaments curling outward from disassembling microtubule tips.Elife2017
28697331A Tubulin Binding Switch Underlies Kip3/Kinesin-8 Depolymerase Activity.Dev Cell2017
27050617May I check your cap?Elife2016
27146111GDP-to-GTP exchange on the microtubule end can contribute to the frequency of catastrophe.Mol Biol Cell2016
26439009A mutation uncouples the tubulin conformational and GTPase cycles, revealing allosteric control of microtubule dynamics.Elife2015
24633327Regulation of microtubule motors by tubulin isotypes and post-translational modifications.Nat Cell Biol2014
25385183The contribution of αβ-tubulin curvature to microtubule dynamics.J Cell Biol2014
25097237A tethered delivery mechanism explains the catalytic action of a microtubule polymerase.Elife2014
22904013A TOG:αβ-tubulin complex structure reveals conformation-based mechanisms for a microtubule polymerase.Science2012
21888381Design, overexpression, and purification of polymerization-blocked yeast αβ-tubulin mutants.Biochemistry2011
17978090The structure of the gamma-tubulin small complex: implications of its architecture and flexibility for microtubule nucleation.Mol Biol Cell2008
18462680Multiple conformations of E. coli Hsp90 in solution: insights into the conformational dynamics of Hsp90.Structure2008
18388201The lattice as allosteric effector: structural studies of alphabeta- and gamma-tubulin clarify the role of GTP in microtubule assembly.Proc Natl Acad Sci U S A2008
15917813Insights into microtubule nucleation from the crystal structure of human gamma-tubulin.Nature2005
12372266Centriole duplication: centrin in on answers?Curr Biol2002
11053839Single-wavelength anomalous diffraction phasing revisited.Acta Crystallogr D Biol Crystallogr2000
10511798Annealing in crystallography: a powerful optimization tool.Prog Biophys Mol Biol1999
10445030Crystal structure of the vesicular transport protein Sec17: implications for SNAP function in SNARE complex disassembly.Mol Cell1999
10024461Experimentally based orientational refinement of membrane protein models: A structure for the Influenza A M2 H+ channel.J Mol Biol1999
10048921Folding intermediates of SNARE complex assembly.Nat Struct Biol1999
9818265Recent developments for the efficient crystallographic refinement of macromolecular structures.Curr Opin Struct Biol1998
9757107Crystallography & NMR system: A new software suite for macromolecular structure determination.Acta Crystallogr D Biol Crystallogr1998
9083112New applications of simulated annealing in X-ray crystallography and solution NMR.Structure1997
18488313Crystallographic refinement by simulated annealing: methods and applications.Methods Enzymol1997
9164463Crystal structure of the two RNA binding domains of human hnRNP A1 at 1.75 A resolution.Nat Struct Biol1997
9195974Analysis of a yeast SNARE complex reveals remarkable similarity to the neuronal SNARE complex and a novel function for the C terminus of the SNAP-25 homolog, Sec9.J Biol Chem1997
9424305Torsion-angle molecular dynamics as a new efficient tool for NMR structure calculation.J Magn Reson1997
9326367Formation of a yeast SNARE complex is accompanied by significant structural changes.FEBS Lett1997
7613463Proline cis-trans isomerization in staphylococcal nuclease: multi-substrate free energy perturbation calculations.Protein Sci1995
7984624Torsion angle dynamics: reduced variable conformational sampling enhances crystallographic structure refinement.Proteins1994
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Collaborators

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Lawrence Berkeley National Laboratory
Co-authored papers 5
UT Southwestern Medical Center
Co-authored papers 4
McGill University
Co-authored papers 2
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Co-authored papers 2
University of Washington
Co-authored papers 2
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Co-authored papers 2
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TheScripps Research Institute
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Co-authored papers 1
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Quantitative Biomedical Research Center
Co-authored papers 1
Utrecht University
Co-authored papers 1
Cambridge Institute for Medical Research, University of Cambridge
Co-authored papers 1
Harvard Medical School
Co-authored papers 1
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Co-authored papers 1
University of California san francisco
Co-authored papers 1
University of Texas Southwestern Medical Center
Co-authored papers 1
Institut Pasteur
Co-authored papers 1