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Author Details

Lukas Chavez
University of California San Diego
2008
71
42
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
370855393D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma.Nat Commun2023
37945900Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma.Nat Genet2023
370855393D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma.Nat Commun2023
37945900Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma.Nat Genet2023
34615656Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells.Cancer Discov2022
34615656Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells.Cancer Discov2022
32822486Reduced chromatin binding of MYC is a key effect of HDAC inhibition in MYC amplified medulloblastoma.Neuro Oncol2021
33762301Notch Signaling between Cerebellar Granule Cell Progenitors.eNeuro2021
32822486Reduced chromatin binding of MYC is a key effect of HDAC inhibition in MYC amplified medulloblastoma.Neuro Oncol2021
33428749PTEN deficiency leads to proteasome addiction: a novel vulnerability in glioblastoma.Neuro Oncol2021
33762301Notch Signaling between Cerebellar Granule Cell Progenitors.eNeuro2021
33428749PTEN deficiency leads to proteasome addiction: a novel vulnerability in glioblastoma.Neuro Oncol2021
32703768The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies.Cancer Discov2020
32703768The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies.Cancer Discov2020
30326163Integrated molecular characterization of IDH-mutant glioblastomas.Neuropathol Appl Neurobiol2019
31624378Publisher Correction: Innate-like functions of natural killer T cell subsets result from highly divergent gene programs.Nat Immunol2019
31754034Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression.Proc Natl Acad Sci U S A2019
30595504Comprehensive Analysis of Chromatin States in Atypical Teratoid/Rhabdoid Tumor Identifies Diverging Roles for SWI/SNF and Polycomb in Gene Regulation.Cancer Cell2019
30326163Integrated molecular characterization of IDH-mutant glioblastomas.Neuropathol Appl Neurobiol2019
30704404InTAD: chromosome conformation guided analysis of enhancer target genes.BMC Bioinformatics2019
31477715YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis.Nat Commun2019
31455674Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock.Cancer Discov2019
31076851Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes.Acta Neuropathol2019
30948495Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma.J Exp Med2019
31754034Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression.Proc Natl Acad Sci U S A2019
31455674Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock.Cancer Discov2019
31624378Publisher Correction: Innate-like functions of natural killer T cell subsets result from highly divergent gene programs.Nat Immunol2019
31477715YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis.Nat Commun2019
30948495Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma.J Exp Med2019
30704404InTAD: chromosome conformation guided analysis of enhancer target genes.BMC Bioinformatics2019
31076851Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes.Acta Neuropathol2019
30595504Comprehensive Analysis of Chromatin States in Atypical Teratoid/Rhabdoid Tumor Identifies Diverging Roles for SWI/SNF and Polycomb in Gene Regulation.Cancer Cell2019
28990704Epithelioid glioblastomas stratify into established diagnostic subsets upon integrated molecular analysis.Brain Pathol2018
28990704Epithelioid glioblastomas stratify into established diagnostic subsets upon integrated molecular analysis.Brain Pathol2018
30030436Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma.Nat Commun2018
30349086A biobank of patient-derived pediatric brain tumor models.Nat Med2018
30205043Aberrant ERBB4-SRC Signaling as a Hallmark of Group 4 Medulloblastoma Revealed by Integrative Phosphoproteomic Profiling.Cancer Cell2018
30006355Desmoplastic Infantile Ganglioglioma/Astrocytoma (DIG/DIA) Are Distinct Entities with Frequent BRAFV600 Mutations.Mol Cancer Res2018
29909548Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas.Acta Neuropathol2018
30332335Extensive Molecular and Clinical Heterogeneity in Patients With Histologically Diagnosed CNS-PNET Treated as a Single Entity: A Report From the Children's Oncology Group Randomized ACNS0332 Trial.J Clin Oncol2018
29489754The landscape of genomic alterations across childhood cancers.Nature2018
29440261Dynamic EBF1 occupancy directs sequential epigenetic and transcriptional events in B-cell programming.Genes Dev2018
29753700Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.Lancet Oncol2018
29258295Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling.Nature2018
29435664Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation.Acta Neuropathol2018
29551561Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma.Dev Cell2018
29539639DNA methylation-based classification of central nervous system tumours.Nature2018
31105932An accessible GenePattern notebook for the copy number variation analysis of Illumina Infinium DNA methylation arrays.F1000Res2018
29909548Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas.Acta Neuropathol2018
30205043Aberrant ERBB4-SRC Signaling as a Hallmark of Group 4 Medulloblastoma Revealed by Integrative Phosphoproteomic Profiling.Cancer Cell2018
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Collaborators

Stefan M Pfister
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 29
Marcel Kool
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 25
Andrey Korshunov
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 22
David T W Jones
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 21
David Capper
Charite University Medicine Berlin
Co-authored papers 13
Anjana Rao
La Jolla Institute for Immunology
Co-authored papers 13
Paul A Northcott
St Jude Children's Research Hospital
Co-authored papers 12
Peter Lichter
German Cancer Research Center (DKFZ)
Co-authored papers 12
Michael D Taylor
The Hospital for Sick Children
Co-authored papers 11
Andreas von Deimling
Co-authored papers 10
Dominik Sturm
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 10
Kristian W Pajtler
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg University
Co-authored papers 9
Tanvi Sharma
Boston Children's Hospital
Co-authored papers 9
Marina Ryzhova
N.N. Burdenko Neurosurgical Institute
Co-authored papers 9
Amar Gajjar
St. Jude Children's Research Hospital
Co-authored papers 8
Serap Erkek
Co-authored papers 8
Till Milde
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 7
Jan O Korbel
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 7
Vijay Ramaswamy
Hospital for Sick Children
Co-authored papers 7
Jeremy N Rich
UPMC Hillman Cancer Center, University of Pittsburgh Medical Center
Co-authored papers 7
Marc Zapatka
Co-authored papers 7
Sebastian Brabetz
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 7
Konstantin Okonechnikov
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 7
Arie Perry
University of California san francisco
Co-authored papers 6
Roland Eils
Berlin Institute of Health (BIH) and Charite
Co-authored papers 6
Nada Jabado
McGill University Health Centre (MUHC), Montreal Children's Hospital (MCH)
Co-authored papers 6
Ivo Buchhalter
German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK)
Co-authored papers 6
Ralf Herwig
Max Planck Institute for Molecular Genetics
Co-authored papers 6
Olaf Witt
Hopp Children's Cancer Center Heidelberg (KiTZ)
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Felix Sahm
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Release 1.2