Author details

Full Name

Cisca Wijmenga

Affiliation

ORCID

Career Start Year

1990

Papers

577

H Index

128

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37164013	Phage display sequencing reveals that genetic, environmental, and intrinsic factors influence variation of human antibody epitope repertoire.	Immunity	2023
37649224	Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity.		2023
37637104	Impact of occupational pesticide exposure on the human gut microbiome.		2023
37337107	Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy.	Nat Genet	2023
36746737	iPSC-derived organ-on-a-chip models for personalized human genetics and pharmacogenomics studies.	Trends Genet	2023
37164015	Phage-display immunoprecipitation sequencing of the antibody epitope repertoire in inflammatory bowel disease reveals distinct antibody signatures.	Immunity	2023
34821391	An integrative genomics approach identifies KDM4 as a modulator of trained immunity.	Eur J Immunol	2022
36044594	Gut microbiome dysbiosis is associated with increased mortality after solid organ transplantation.	Science Translational Medicine	2022
35841871	Transcriptional profiles predict treatment outcome in patients with tuberculosis and diabetes at diagnosis and at two weeks after initiation of anti-tuberculosis treatment.	eBioMedicine	2022
36035246	Omics-informed CNV calls reduce false-positive rates and improve power for CNV-trait associations.	HGG Adv	2022
35446234	Integrated fecal microbiome-metabolome signatures reflect stress and serotonin metabolism in irritable bowel syndrome.	Gut Microbes	2022
35638288	A genome-wide functional genomics approach uncovers genetic determinants of immune phenotypes in type 1 diabetes.	eLife	2022
36216932	Influence of the microbiome, diet and genetics on inter-individual variation in the human plasma metabolome.	Nat Med	2022
35371081	Single-Cell RNA Sequencing of Peripheral Blood Mononuclear Cells From Pediatric Coeliac Disease Patients Suggests Potential Pre-Seroconversion Markers.	Frontiers in Immunology	2022
35681050	Genetic, parental and lifestyle factors influence telomere length.	Communications Biology	2022
35418674	Environmental factors shaping the gut microbiome in a Dutch population.	Nature	2022
36522747	Systematic analysis of relationships between plasma branched-chain amino acid concentrations and cardiometabolic parameters: an association and Mendelian randomization study.		2022
35021085	Discovery, diversity, and functional associations of crAss-like phages in human gut metagenomes from four Dutch cohorts.	Cell Reports	2022
34475573	Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression.	Nat Genet	2021
32333097	Habitual dietary intake of IBD patients differs from population controls: a case-control study.	Eur J Nutr	2021
33811041	Long-term dietary patterns are associated with pro-inflammatory and anti-inflammatory features of the gut microbiome.	Gut	2021
34010651	Stability of the human gut virome and effect of gluten-free diet.	Cell Reports	2021
34282338	Population-wide diversity and stability of serum antibody epitope repertoires against human microbiota.	Nat Med	2021
34229738	Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease.	Genome Biol	2021
33893454	From LD-based mapping to GWAS.	Nature Reviews Genetics	2021
33737436	Lifelines COVID-19 cohort: investigating COVID-19 infection and its health and societal impacts in a Dutch population-based cohort.	BMJ Open	2021
33838112	The long-term genetic stability and individual specificity of the human gut microbiome.	Cell	2021
33569077	Systematic Prioritization of Candidate Genes in Disease Loci Identifies <i>TRAFD1</i> as a Master Regulator of IFNÎ³ Signaling in Celiac Disease.	Front Genet	2021
33462485	Large-scale association analyses identify host factors influencing human gut microbiome composition.	Nat Genet	2021
33515008	The Composition and Metabolic Potential of the Human Small Intestinal Microbiota Within the Context of Inflammatory Bowel Disease.		2021
33831035	Patient attitudes towards faecal sampling for gut microbiome studies and clinical care reveal positive engagement and room for improvement.	PLoS ONE	2021
33927210	Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells.	Sci Rep	2021
34313538	A combination of fecal calprotectin and human beta-defensin 2 facilitates diagnosis and monitoring of inflammatory bowel disease.	Gut Microbes	2021
32651235	Whole exome sequencing analyses reveal gene-microbiota interactions in the context of IBD.	Gut	2021
33338541	Shared DNA methylation signatures in childhood allergy: The MeDALL study.	Journal of Allergy and Clinical Immunology	2021
33218785	Non-classical clinical presentation at diagnosis by male celiac disease patients of older age.	European Journal of Internal Medicine	2021
33393726	Genetic Association of a Gain-of-Function IFNGR1 Polymorphism and the Intergenic Region LNCAROD/DKK1 With BehÃ§et's Disease.	Arthritis Rheumatol	2021
34512620	Inflammatory Protein Profiles in Plasma of Candidaemia Patients and the Contribution of Host Genetics to Their Variability.	Front Immunol	2021
34847370	Characterization of gut microbial structural variations as determinants of human bile acid metabolism.		2021
34440652	Long Non-Coding RNAs Involved in Progression of Non-Alcoholic Fatty Liver Disease to Steatohepatitis.	Cells	2021
34768815	A Combined mRNA- and miRNA-Sequencing Approach Reveals miRNAs as Potential Regulators of the Small Intestinal Transcriptome in Celiac Disease.	International Journal of Molecular Sciences	2021
34950132	Circulating miRNAs as Potential Biomarkers for Celiac Disease Development.	Front Immunol	2021
33269293	Genome-Wide Association Study Identifies Novel Colony Stimulating Factor 1 Locus Conferring Susceptibility to Cryptococcosis in Human Immunodeficiency Virus-Infected South Africans.	Open Forum Infect Dis	2020
31909512	Systematic review with meta-analysis: the risks of proton pump inhibitors during pregnancy.	Alimentary Pharmacology and Therapeutics	2020
31591516	Immunochip meta-analysis in European and Argentinian populations identifies two novel genetic loci associated with celiac disease.	Eur J Hum Genet	2020
31953381	Impact of commonly used drugs on the composition and metabolic function of the gut microbiota.	Nature Communications	2020
32100173	Lifelines NEXT: a prospective birth cohort adding the next generation to the three-generation Lifelines cohort study.	European Journal of Epidemiology	2020
32033836	Tissue alarmins and adaptive cytokine induce dynamic and distinct transcriptional responses in tissue-resident intraepithelial cytotoxic T lymphocytes.	Journal of Autoimmunity	2020
33371313	Practical Barriers and Facilitators Experienced by Patients, Pharmacists and Physicians to the Implementation of Pharmacogenomic Screening in Dutch Outpatient Hospital Care-An Explorative Pilot Study.	Journal of Personalized Medicine	2020
33079603	Metabolic Age Based on the BBMRI-NL <sup>1</sup>H-NMR Metabolomics Repository as Biomarker of Age-related Disease.	Circ Genom Precis Med	2020